References
- Fisher B, Wolmark N, Rockette H, et al. Postoperative adjuvant chemotherapy or radiation therapy for retal cancer: results from NSABP protocol R-01. J Natl Cancer Inst 1988; 80: 21–29
- Gastrointestinal Tumor Study Group. Prolongation of the disease-free interval in surgically treated rectal carcinoma. N Engl J Med 1985; 312: 1465–72
- Krook I E, Moertel C G, Gunderson L L, et al. Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 1991; 324: 709–15
- National Institutes' of Health Consensus Conference: Adjuvant therapy for patients with colon and rectal cancer. JAMA 1990; 264: 1444–50
- Mohiudin M, Marks G. Adjuvant radiation therapy for colon and rectal cancer. Semin Oncol 1991; 18: 411–20
- Steele G. Combined-modality therapy for rectal carcinoma—The time has come (Editorial). N Engl J Med 1991; 324: 764–6
- Anonymous. Advanced colorectal cancer meta-analysis project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J Clin Oncol 1992; 10: 896–903
- Buroker T R, O'Connell M J, Wieand H S, et al. Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer. J Clin Oncol 1994; 12: 14–20
- Bosset J F, Pavy J J, Hamers H P, et al. Determination of optimal dose of 5-fluorouracil when combined with low doseleucovorin and irradiation in rectal cancer: Results of three consecutive phase II studies. Eur J Cancer 1993; 29 A: 1406–10
- Cascinu S, Veraldi A, Foglietti G P, et al. A pilot clinical trial of surgical adjuvant treatment with high-dose 6S-leucovorin/5-fluorouracii and radiation therapy for high-risk rectal carcinoma. Tumori 1994; 80: 335–8
- Minsky B D, Cohen A M, Enker W E, et al. Phase I trial of postoperative 5-FU, radiation therapy, and high dose leucovorin for resectable rectal cancer. Int J Radiat Oncol Biol Phys 1992; 22: 139–145
- Martenson J A, Urias R, Smalley S R. Radiation therapy quality control in a clinical trial of adjuvant postoperative treatment for rectal cancer. Int J Radiat Oncol Biol Phys 1995; 32: 51–5
- Gunderson L L, Rusell A H, Llevellyn H J, Doppke K P, Tepper J E. Treatment planning for colorectal cancer: radiation and surgical techniques and value of small-bowel films. Int J Radiat Oncol Biol Phys 1985; 11: 1379–93
- Miller A B, Hoodgstraten B, Slaquel M, Winkler A. Reporting results of cancer treatment. Cancer 1980; 47: 207–14
- Kaplan E L, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457–81
- Waxman S, Bruckner H. The enhancement of 5-fluorouracil antimetabolic aclivity by leucovorin, menadione and alphatocopherol. Eur J Cancer Clin Oncol 1982; 18: 685–92
- Erlichman C, Fine S, Wong A, Elhakim T. A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma. J Clin Oncol 1988; 6: 469–75
- Poon M A, O'Connell M J, Wieand H S. Biochemical modulation of fluorouracil with leucovorin: Confirmatory evidence of improved therapeutic efficacy in advaced colorectal cancer. J Clin Oncol 1991; 9: 1967–72
- Wolmark N, Rockette H, Fisher B, et al. The benefit of leucovorin-modulaled fluorouracil as postoperative adjuvant therapy for primary colon cancer: Results from National Surgical Adjuvant Breast and Bowel Project Protocol C-03. J Clin Oncol 1993; 11: 1879–87
- Minsky B D, Cohen A M, Enker W E, Kelsen D P, Kemeny N, Frankel J. Efficacy of postoperative 5-FU, high-dose leucovorin, and sequential radiation therapy for clinically resectable rectal cancer. Cancer Invest 1995; 13: 1–7
- O'Connell M J, Martenson J A, Wieand H S, et al. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994; 331: 502–7
- Brierley J D, Cummings B J, Wong C S, Mc Lean M, Cashell A, Manter S. The variation of small bowell volume within the pelvis before and during adjuvant radiation for rectal cancer. Radiother Oncol 1994; 31: 110–6
- Minsky B D, Conti J A, Huang Y, Knopf K. Relationship of acute gastointestinal loxicity and the volume of irradiated small bowel in patients receiving combined modality therapy for rectal cancer. J Clin Oncol 1995; 13: 1409–16