Osteopontin but not parathyroid hormone-related protein predicts prognosis in human renal cell carcinoma

References

• Fedarko NS, Jain A, Karadag A, Fisher LW. Three small integrin binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J 2004;18:734–6.
   PubMed Web of Science ®Google Scholar
• Brown LF, Berse B, Van de Water L, Papadopoulos- Sergiou A, Perruzzi CA, Manseau EJ, . Expression and distribution of osteopontin in human tissues: Widespread association with luminal epithelial surfaces. Mol Biol Cell 1992;3:1169–80.
   PubMed Web of Science ®Google Scholar
• Denhardt DT, Noda M. Osteopontin expression and function: Role in bone remodeling. J Cell Biochem Suppl 1998;30–31:92–102.
   PubMedGoogle Scholar
• Denhardt DT, Guo X. Osteopontin: A protein with diverse functions. FASEB J 1993;7:1475–82.
   PubMed Web of Science ®Google Scholar
• Zhu Y, Denhardt DT, Cao H, Sutphin PD, Koong AC, Giaccia AJ, . Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene 2005;24:6555–63.
   PubMed Web of Science ®Google Scholar
• Le QT, Sutphin PD, Raychaudhuri S, Yu SC, Terris DJ, Lin HS, . Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clin Cancer Res 2003;9:59–67.
   PubMed Web of Science ®Google Scholar
• Oates AJ, Barraclough R, Rudland PS. The role of osteopontin in tumorigenesis and metastasis. Invasion Metastasis 1997;17:1–15.
   PubMedGoogle Scholar
• Tuck AB, Chambers AF, Allan AL. Osteopontin overexpression in breast cancer: Knowledge gained and possible implications for clinical management. J Cell Biochem 2007; 102:859–68.
   PubMed Web of Science ®Google Scholar
• Zhang DT, Yuan J, Yang L, Guo XN, Hao ZM, Han ZY, . [Osteopontin expression and its relation to invasion and metastases in gastric cancer]. Zhonghua Zhong Liu Za Zhi 2005;27:167–9.
   PubMedGoogle Scholar
• Chambers AF, Wilson SM, Kerkvliet N, O’Malley FP, Harris JF, Casson AG. Osteopontin expression in lung cancer. Lung Cancer 1996;15:311–23.
   PubMed Web of Science ®Google Scholar
• Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, . Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst 2002;94:513–21.
   PubMed Web of Science ®Google Scholar
• Matusan K, Dordevic G, Stipic D, Mozetic V, Lucin K. Osteopontin expression correlates with prognostic variables and survival in clear cell renal cell carcinoma. J Surg Oncol 2006;94:325–31.
   PubMed Web of Science ®Google Scholar
• Matusan K, Dordevic G, Mozetic V, Lucin K. Expression of osteopontin and CD44 molecule in papillary renal cell tumors. Pathol Oncol Res 2005;11:108–13.
   PubMed Web of Science ®Google Scholar
• Ramankulov A, Lein M, Kristiansen G, Meyer HA, Loening SA, Jung K. Elevated plasma osteopontin as marker for distant metastases and poor survival in patients with renal cell carcinoma. J Cancer Res Clin Oncol 2007;133:643–52.
   PubMed Web of Science ®Google Scholar
• Strewler GJ. The physiology of parathyroid hormone-related protein. N Engl J Med 2000;342:177–85.
   PubMed Web of Science ®Google Scholar
• Danks JA, Ebeling PR, Hayman J, Chou ST, Moseley JM, Dunlop J, . Parathyroid hormone-related protein: Immunohistochemical localization in cancers and in normal skin. J Bone Miner Res 1989;4:273–8.
   PubMed Web of Science ®Google Scholar
• Tsuchihashi T, Yamaguchi K, Miyake Y, Otsubo K, Nagasaki K, Honda S, . Parathyroid hormone-related protein in tumor tissues obtained from patients with humoral hypercalcemia of malignancy. J Natl Cancer Inst 1990;82:40–4.
   PubMedGoogle Scholar
• Honda S, Yamaguchi K, Suzuki M, Sato Y, Adachi I, Kimura S, . Expression of parathyroid hormone-related protein mRNA in tumors obtained from patients with humoral hypercalcemia of malignancy. Jpn J Cancer Res 1988;79:677–81.
   PubMedGoogle Scholar
• Burtis WJ, Brady TG, Orloff JJ, Ersbak JB, Warrell RP, Jr., Olson BR, . Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N Engl J Med 1990;322: 1106–12.
   PubMed Web of Science ®Google Scholar
• Grill V, Rankin W, Martin TJ. Parathyroid hormone-related protein (PTHrP) and hypercalcaemia. Eur J Cancer 1998; 34:222–9.
   PubMed Web of Science ®Google Scholar
• Massfelder T, Lang H, Schordan E, Lindner V, Rothhut S, Welsch S, . Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene. Cancer Res 2004;64:180–8.
   PubMed Web of Science ®Google Scholar
• Gotoh A, Kitazawa S, Mizuno Y, Takenaka A, Arakawa S, Matsumoto O, . Common expression of parathyroid hormone-related protein and no correlation of calcium level in renal cell carcinomas. Cancer 1993;71:2803–6.
   PubMed Web of Science ®Google Scholar
• Iwamura M, Wu W, Muramoto M, Ohori M, Egawa S, Uchida T, . Parathyroid hormone-related protein is an independent prognostic factor for renal cell carcinoma. Cancer 1999;86:1028–34.
   PubMed Web of Science ®Google Scholar
• Papworth K, Grankvist K, Ljungberg B, Rasmuson T. Parathyroid hormone-related protein and serum calcium in patients with renal cell carcinoma. Tumour Biol 2005; 26:201–6.
   PubMed Web of Science ®Google Scholar
• Yasui T, Fujita K, Sasaki S, Iguchi M, Hirota S, Nomura S, . Alendronate inhibits osteopontin expression enhanced by parathyroid hormone-related peptide (PTHrP) in the rat kidney. Urol Res 1998;26:355–60.
   PubMedGoogle Scholar
• Allan A, Tuck A, Bramwell V, Vandenberg T, Winquist E, Chambers A. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis 2005:107–23.
   Google Scholar
• Liao J, McCauley LK. Skeletal metastasis: Established and emerging roles of parathyroid hormone related protein (PTHrP). Cancer Metastasis Rev 2006;25:559–71.
   PubMed Web of Science ®Google Scholar
• Ono N, Nakashima K, Rittling SR, Schipani E, Hayata T, Soma K, . Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts. J Biol Chem 2008;283:19400–9.
   PubMed Web of Science ®Google Scholar
• Kovacs G, Akhtar M, Beckwith BJ, Bugert P, Cooper CS, Delahunt B, . The Heidelberg classification of renal cell tumours. J Pathol 1997;183:131–3.
   PubMed Web of Science ®Google Scholar
• Sobin L WC, International Union Against Cancer (UICC), editor. TNM classification of malignant tumours, 6th ed. Hoboken, NJ: John Wiley & Sons; 2002.
   Google Scholar
• Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982;6:655–63.
   PubMed Web of Science ®Google Scholar
• Emly JF, Gregory J, Bowden SJ, Ahmed A, Whittle MJ, Rushton DI, . Immunohistochemical localization of parathyroid hormone-related protein (PTHrP) in human term placenta and membranes. Placenta 1994;15:653–60.
   PubMed Web of Science ®Google Scholar
• Sandlund J, Hedberg Y, Bergh A, Grankvist K, Ljungberg B, Rasmuson T. Evaluation of CD31 (PECAM-1) expression using tissue microarray in patients with renal cell carcinoma. Tumour Biol 2007;28:158–64.
   PubMed Web of Science ®Google Scholar
• Budayr AA, Nissenson RA, Klein RF, Pun KK, Clark OH, Diep D, . Increased serum levels of a parathyroid hormone-like protein in malignancy-associated hypercalcemia. Ann Intern Med 1989;111:807–12.
   PubMed Web of Science ®Google Scholar
• Wai PY, Kuo PC. Osteopontin: Regulation in tumor metastasis. Cancer Metastasis Rev 2008;27:103–18.
   PubMed Web of Science ®Google Scholar
• Ramankulov A, Lein M, Kristiansen G, Loening SA, Jung K. Plasma osteopontin in comparison with bone markers as indicator of bone metastasis and survival outcome in patients with prostate cancer. Prostate 2007;67:330–40.
   PubMed Web of Science ®Google Scholar
• Le QT, Denko NC, Giaccia AJ. Hypoxic gene expression and metastasis. Cancer Metastasis Rev 2004;23:293–310.
   PubMed Web of Science ®Google Scholar
• Delahunt B, Bethwaite PB, Thornton A. Prognostic significance of microscopic ascularity for clear cell renal cell carcinoma. Br J Urol 1997;80:401–4.
   PubMedGoogle Scholar
• Hiraki A, Ueoka H, Bessho A, Segawa Y, Takigawa N, Kiura K, . Parathyroid hormone-related protein measured at the time of first visit is an indicator of bone metastases and survival in lung carcinoma patients with hypercalcemia. Cancer 2002;95:1706–13.
   PubMed Web of Science ®Google Scholar
• Henderson M, Danks J, Moseley J, Slavin J, Harris T, McKinlay M, . Parathyroid hormone-related protein production by breast cancers, improved survival, and reduced bone metastases. J Natl Cancer Inst 2001;93:234–7.
   PubMedGoogle Scholar