A literature-based meta-analysis of clinical risk factors for development of radiation induced pneumonitis

References

• Baumann M. Impact of endogenous and exogenous factors on radiation sequelae. In: Dunst JSR, editor. Late sequelae in oncology. Berlin-Heidelberg: Springer Verlag; 1995. pp. 3–12.
   Google Scholar
• Bentzen SM, Overgaard J. Patient-to-patient variability in the expression of radiation-induced normal tissue injury. Semin Radiat Oncol 1994;4:68–80.
   PubMedGoogle Scholar
• Bentzen SM. Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology. Nat Rev Cancer 2006;6:702–13.
   PubMed Web of Science ®Google Scholar
• Marks LB, Bentzen SM, Deasy JO, Kong FM, Bradley JD, Vogelius IS, . Radiation dose-volume effects in the lung. Int J Radiat Oncol Biol Phys 2010;76(3 Suppl):S70–6.
   PubMed Web of Science ®Google Scholar
• Bradley JD, Hope A, El Naqa I, Apte A, Lindsay PE, Bosch W, . A nomogram to predict radiation pneumonitis, derived from a combined analysis of RTOG 9311 and institutional data. Int J Radiat Oncol Biol Phys 2007;69: 985–92.
   PubMed Web of Science ®Google Scholar
• Seppenwoolde Y, Lebesque JV. Partial irradiation of the lung. Semin Radiat Oncol 2001;11:247–58.
   Google Scholar
• Review Manager (RevMan) [computer program].Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration; 2008.
   Google Scholar
• Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327:557–60.
   PubMed Web of Science ®Google Scholar
• Clenton SJ, Fisher PM, Conway J, Kirkbride P, Hatton MQ. The use of lung dose-volume histograms in predicting post-radiation pneumonitis after non-conventionally fractionated radiotherapy for thoracic carcinoma. Clin Oncol (R Coll Radiol) 2005;17:599–603.
   PubMedGoogle Scholar
• Fay M, Tan A, Fisher R, Mac MM, Wirth A, Ball D. Dose-volume histogram analysis as predictor of radiation pneumonitis in primary lung cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys 2005;61:1355–63.
   PubMed Web of Science ®Google Scholar
• Kubo A, Osaki K, Kawanaka T, Furutani S, Ikushima H, Nishitani H. Risk factors for radiation pneumonitis caused by whole breast irradiation following breast-conserving surgery. J Med Invest 2009;56:99–110.
   PubMedGoogle Scholar
• Robnett TJ, Machtay M, Vines EF, McKenna MG, Algazy KM, McKenna WG. Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer. Int J Radiat Oncol Biol Phys 2000; 48:89–94.
   PubMed Web of Science ®Google Scholar
• Seppenwoolde Y, De JK, Boersma LJ, Belderbos JS, Lebesque JV. Regional differences in lung radiosensitivity after radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2004;60:748–58.
   PubMedGoogle Scholar
• Kim TH, Cho KH, Pyo HR, Lee JS, Zo JI, Lee DH, . Dose-volumetric parameters for predicting severe radiation pneumonitis after three-dimensional conformal radiation therapy for lung cancer. Radiology 2005;235:208–15.
   PubMed Web of Science ®Google Scholar
• Monson JM, Stark P, Reilly JJ, Sugarbaker DJ, Strauss GM, Swanson SJ, . Clinical radiation pneumonitis and radiographic changes after thoracic radiation therapy for lung carcinoma. Cancer 1998;82:842–50.
   PubMedGoogle Scholar
• Moreno M, Aristu J, Ramos LI, Arbea L, López-Picazo JM, Cambeiro M, . Predictive factors for radiation-induced pulmonary toxicity after three-dimensional conformal chemoradiation in locally advanced non-small-cell lung cancer. Clin Transl Oncol 2007;9:596–602.
   Google Scholar
• Rancati T, Ceresoli GL, Gagliardi G, Schipani S, Cattaneo GM. Factors predicting radiation pneumonitis in lung cancer patients: A retrospective study. Radiother Oncol 2003;67: 275–83.
   PubMed Web of Science ®Google Scholar
• Wang S, Liao Z, Wei X, Liu HH, Tucker SL, Hu C, . Association between systemic chemotherapy before chemoradiation and increased risk of treatment-related pneumonitis in esophageal cancer patients treated with definitive chemoradiotherapy. J Thorac Oncol 2008;3:277–82.
   Google Scholar
• Das SK, Zhou S, Zhang J, Yin FF, Dewhirst MW, Marks LB. Predicting lung radiotherapy-induced pneumonitis using a model combining parametric Lyman probit with nonparametric decision trees. Int J Radiat Oncol Biol Phys 2007;68:1212–21.
   Google Scholar
• Nakamura T, Fuwa N, Kodaira T, Tachibana H, Tomoda T, Nakahara R, . Clinical outcome of stage III non- small-cell lung cancer patients after definitive radiotherapy. Lung 2008;186:91–6.
   Google Scholar
• Claude L, Perol D, Ginestet C, Falchero L, Arpin D, Vincent M, . A prospective study on radiation pneumonitis following conformal radiation therapy in non-small-cell lung cancer: Clinical and dosimetric factors analysis. Radiother Oncol 2004;71:175–81.
   PubMed Web of Science ®Google Scholar
• Kocak Z, Yu X, Zhou SM, D’Amico TA, Hollis D, Kahn D, . The impact of pre-radiotherapy surgery on radiation-induced lung injury. Clin Oncol (R Coll Radiol) 2005; 17:210–6.
   Google Scholar
• Muller G, Kiricuta IC, Stiess J, Bohndorf W. [Radiation pneumonitis and pulmonary fibrosis after the CT-planned radiotherapy of bronchial carcinoma]. Strahlenther Onkol 1994;170:400–7.
   Google Scholar
• Anscher MS, Kong FM, Andrews K, Clough R, Marks LB, Bentel G, . Plasma transforming growth factor beta1 as a predictor of radiation pneumonitis. Int J Radiat Oncol Biol Phys 1998;41:1029–35.
   PubMed Web of Science ®Google Scholar
• Hernando ML, Marks LB, Bentel GC, Zhou SM, Hollis D, Das SK, . Radiation-induced pulmonary toxicity: A dose-volume histogram analysis in 201 patients with lung cancer. Int J Radiat Oncol Biol Phys 2001;51:650–9.
   PubMed Web of Science ®Google Scholar
• Hope AJ, Lindsay PE, El Naqa I, Alaly JR, Vicic M, Bradley JD, . Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters. Int J Radiat Oncol Biol Phys 2006;65:112–24.
   PubMed Web of Science ®Google Scholar
• Inoue A, Kunitoh H, Sekine I, Sumi M, Tokuuye K, Saijo N. Radiation pneumonitis in lung cancer patients: A retrospective study of risk factors and the long-term prognosis. Int J Radiat Oncol Biol Phys 2001;49:649–55.
   PubMed Web of Science ®Google Scholar
• Novakova-Jiresova A, Van Gameren MM, Coppes RP, Kampinga HH, Groen HJ. Transforming growth factor-beta plasma dynamics and post-irradiation lung injury in lung cancer patients. Radiother Oncol 2004; 71:183–9.
   PubMed Web of Science ®Google Scholar
• Segawa Y, Takigawa N, Kataoka M, Takata I, Fujimoto N, Ueoka H. Risk factors for development of radiation pneumonitis following radiation therapy with or without chemotherapy for lung cancer. Int J Radiat Oncol Biol Phys 1997;39:91–8.
   Google Scholar
• Tucker SL, Liu HH, Liao Z, Wei X, Wang S, Jin H, . Analysis of radiation pneumonitis risk using a generalized Lyman model. Int J Radiat Oncol Biol Phys 2008;72: 568–74.
   PubMed Web of Science ®Google Scholar
• Yamada M, Kudoh S, Hirata K, Nakajima T, Yoshikawa J. Risk factors of pneumonitis following chemoradiotherapy for lung cancer. Eur J Cancer 1998;34:71–5.
   PubMed Web of Science ®Google Scholar
• Johansson S, Bjermer L, Franzen L, Henriksson R. Effects of ongoing smoking on the development of radiation-induced pneumonitis in breast cancer and oesophagus cancer patients. Radiother Oncol 1998;49:41–7.
   PubMed Web of Science ®Google Scholar
• Gagliardi G, Bjohle J, Lax I, Ottolenghi A, Eriksson F, Liedberg A, . Radiation pneumonitis after breast cancer irradiation: Analysis of the complication probability using the relative seriality model. Int J Radiat Oncol Biol Phys 2000;46:373–81.
   PubMed Web of Science ®Google Scholar
• Kahan Z, Csenki M, Varga Z, Szil E, Cserháti A, Balogh A, . The risk of early and late lung sequelae after conformal radiotherapy in breast cancer patients. Int J Radiat Oncol Biol Phys 2007;68:673–81.
   PubMed Web of Science ®Google Scholar
• Koga K, Kusumoto S, Watanabe K, Nishikawa K, Harada K, Ebihara H. Age factor relevant to the development of radiation pneumonitis in radiotherapy of lung cancer. Int J Radiat Oncol Biol Phys 1988;14:367–71.
   Google Scholar
• Quon H, Shepherd FA, Payne DG, Coy P, Murray N, Feld R, . The influence of age on the delivery, tolerance, and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1999;43:39–45.
   PubMed Web of Science ®Google Scholar
• Byhardt RW, Scott C, Sause WT, Emami B, Komaki R, Fisher B, . Response, toxicity, failure patterns, and survival in five Radiation Therapy Oncology Group (RTOG) trials of sequential and/or concurrent chemotherapy and radiotherapy for locally advanced non-small-cell carcinoma of the lung. Int J Radiat Oncol Biol Phys 1998; 42:469–78.
   PubMed Web of Science ®Google Scholar
• Fournel P, Robinet G, Thomas P, Souquet PJ, Léna H, Vergnenégre A, . Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Etienne d’Oncologie Thoracique-Groupe Francais de Pneumo-Cancerologie NPC 95-01 Study. J Clin Oncol 2005;23:5910–7.
   PubMed Web of Science ®Google Scholar
• Altman DG, Lausen B, Sauerbrei W, Schumacher M. Dangers of using “optimal” cutpoints in the evaluation of prognostic factors. J Natl Cancer Inst 1994;86:829–35.
   PubMed Web of Science ®Google Scholar
• Naggara O, Raymond J, Guilbert F, Roy D, Weill A, Altman DG. Analysis by categorizing or dichotomizing continuous variables is inadvisable: An example from the natural history of unruptured aneurysms. AJNR Am J Neuroradiol 2011;32:437–40.
   PubMed Web of Science ®Google Scholar
• Bjermer L, Franzen L, Littbrand B, Nilsson K, Angstrom T, Henriksson R. Effects of smoking and irradiated volume on inflammatory response in the lung of irradiated breast cancer patients evaluated with bronchoalveolar lavage. Cancer Res 1990;50:2027–30.
   PubMed Web of Science ®Google Scholar
• Jin H, Tucker SL, Liu HH, Wei X, Yom SS, Wang S, . Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy. Radiother Oncol 2009;91:427–32.
   PubMed Web of Science ®Google Scholar
• Albain KS, Swann RS, Rusch VW, Turrisi AT III, Shepherd FA, Smith C, . Radiotherapy plus chemotherapy with or without surgical resection for stage III non- small-cell lung cancer: A phase III randomised controlled trial. Lancet 2009;374:379–86.
   PubMed Web of Science ®Google Scholar
• Auperin A, Le Péchoux C, Rolland E, Curran WJ, Furuse K, Fournel P, . Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J Clin Oncol 2010;28:2181–90.
   PubMed Web of Science ®Google Scholar
• Appelt AL, Vogelius IR. A method to adjust radiation dose-response relationships for clinical risk factors. Radiother Oncol 2012;102:352–4.
   PubMed Web of Science ®Google Scholar
• Bentzen SM, Trotti A. Evaluation of early and late toxicities in chemoradiation trials. J Clin Oncol 2007;25: 4096–103.
   PubMed Web of Science ®Google Scholar