References
- World Cancer Report 2008. Available from: http://www.iarc.fr/en/publications/pdfs-online/wcr/2008/index.php [cited 2011 March 1]
- Sica A, Allavena P, Mantovani A. Cancer related inflammation: The macrophage connection. Cancer Lett 2008;267:204–15.
- Pollard JW. Tumor-educated macrophages promote tumor progression and metastasis. Nat Rev Cancer 2004;4:71–8.
- Pollard JW. Trophic macrophages in development and disease. Nat Rev Immunol 2009;9:259–70.
- Lissbrant IF, Stattin P, Wikstrom P, Damber JE, Egevad L, Bergh A. Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival. Int J Oncol 2000;17:445–51.
- Ishigami S, Natsugoe S, Tokuda K, Nakajo A, Okumura H, Matsumoto M, et al. Tumor-associated macrophage (TAM) infiltration in gastric cancer. Anticancer Res 2003;23:4079–83.
- Ohno S, Inagawa H, Dhar DK, Fujii T, Ueda S, Tachibana M, et al. The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res 2003;23:5015–522.
- Turner SL, Blair-Zajdel ME, Bunning RA. ADAMs and ADAMTSs in cancer. Br J Biomed Sci 2009;66:117–28.
- Ahonen M, Baker AH, Kahari VM. Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells. Cancer Res 1998;58:2310–5.
- Ahonen M, Baker AH, Kahari VM. The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett 2002;524:154–8.
- Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002;23:549–55.
- Bingle L, Brown NJ, Lewis CE. The role of tumor-associated macrophages in tumor progression: Implications for new anticancer therapies. J Pathol 2002;196:254–65.
- Balkwill F, Charles KA, Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005;7:211–7.
- Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation. Blood 2006;107:2112–22.
- Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony- stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001;193:727–40.
- Zeisberger SM, Odermatt B, Marty C, Zehnder-Fjallman AH, Ballmer-Hofer K, Schwendener RA. Clodronate- liposome-mediated depletion of tumor-associated macrophages: A new and highly effective antiangiogenic therapy approach. Br J Cancer 2006;95:272–81.
- Lewis CE, Pollard JW. Distinct role of macrophagesin different tumor microenvironments. Cancer Res 2006;66:605–12.
- Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, et al. Relation of hypoxia-inducible factor-2 α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res 2002;62:1326–9.
- Leek RD, Landers RJ, Harrism AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 1999;79:991–5.
- Collingridge DR, Hill SA, Chaplin DJ. Proportion of infiltrating IgG binding immune cells predict for tumor hypoxia. Br J Cancer 2001;84:626–30.
- Schioppa T, Uranchimeg B, Saccani A, Biswas SK, Doni A, Rapisarda A, et al. Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 2003;198:1391–402.
- Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, et al. The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 2000;157:411–21.
- Grimshaw MJ, Balkwill FR. Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation— a potential mechanism. Eur J Immunol 2001;31:480–9.
- Ashida N, Arai H, Yamasaki M, Kita T. Differential signaling for MCP-1-dependent integrin activation and chemotaxis. Ann N Y Acad Sci 2001;947:387–9.
- Wain JH, Kirby JA, Ali S. Leucocyte chemotaxis: Examination of mitogen activated protein kinase and phosphoinositide 3-kinase activation by monocyte chemoattractant proteins- 1,-2,-3 and -4. Clin Exp Immunol 2002;127: 436–44.
- Sampieri CL, de la Peña S, Ochoa-Lara M, Zenteno-Cuevas R, León-Córdoba K. Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis. World J Gastroenterol 2010;16:1500–5.
- Folkman, J. Tumor angiogenesis: Therapeutic implications. N Engl J Med 1971;285:1182–6.
- Jedinak A, Dudhgaonkar S, Sliva D. Activated macrophages induce metastatic behavior of colon cancer cells. Immunobiology 2010;215:242–9.
- Chen JJ, Yao PL, Yuan A, Hong TM, Shun CT, Kuo ML, et al Upregulation of tumor interleukin-8 expression by infiltrating macrophages: Its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 2003;9:729–37.
- Chen J, De S, Brainard J, Byzova TV. Metastatic properties of prostate cancer cells are controlled by VEGF. Cell Commun Adhes 2004;11:1–11.