2,090
Views
26
CrossRef citations to date
0
Altmetric
Original Articles

Breast cancer in women 80 years of age and older: A comprehensive analysis of an underreported entity

, , &
Pages 57-65 | Received 23 Jun 2012, Accepted 12 Sep 2012, Published online: 22 Oct 2012

References

  • Albrand G, Terret C. Early breast cancer in the elderly: Assessment and management considerations. Drugs Aging 2008;25:35–45.
  • Biganzoli L, Wildiers H, Oakman C, Marotti L, Loibl S, Kunkler I, . Management of elderly patients with breast cancer: Updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA). Lancet Oncol 2012;13:e148–60.
  • Crivellari D, Aapro M, Leonard R, von Minckwitz G, Brain E, Goldhirsch A, . Breast cancer in the elderly. J Clin Oncol 2007;25:1882–90.
  • Schonberg MA, Marcantonio ER, Li D, Silliman RA, Ngo L, McCarthy EP. Breast cancer among the oldest old: Tumor characteristics, treatment choices, and survival. J Clin Oncol 2010;28:2038–45.
  • Spazzapan S, Crivellari D, Bedard P, Lombardi D, Miolo G, Scalone S, . Therapeutic management of breast cancer in the elderly. Expert Opin Pharmacother 2011;12:945–60.
  • Taylor WC, Muss HB. Recent advances: Adjuvant therapy for older women with breast cancer. Cancer J 2010;16: 289–93.
  • World Health Organization. Health statistics and health information systems. Definition of an older or elderly person. [updated 2012; cited 2012 May 27]. Available from: http://www.who.int/healthinfo/survey/ageingdefnolder/en/index.html.
  • Hamerman D. Toward an understanding of frailty. Ann Intern Med 1999;130:945–50.
  • Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007;25:1824–31.
  • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), Peto R, Davies C, Godwin J, Gray R, Pan H, et al. Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. Lancet 2012;379:432–44.
  • Rao VS, Jameel JK, Mahapatra TK, McManus PL, Fox JN, Drew PJ. Surgery is associated with lower morbidity and longer survival in elderly breast cancer patients over 80. Breast J 2007;13:368–73.
  • Rosenkranz KM, Bedrosian I, Feng L, Hunt KK, Hartman K, Lucci A, . Breast cancer in the very elderly: Treatment patterns and complications in a tertiary cancer center. Am J Surg 2006;192:541–4.
  • Van Leeuwen BL, Rosenkranz KM, Feng LL, Bedrosian I, Hartmann K, Hunt KK, . The effect of under-treatment of breast cancer in women 80 years of age and older. Crit Rev Oncol Hematol 2011;79:315–20.
  • Schmid SM, Modlasiak AA, Myrick ME, Kilic N, Viehl CT, Schotzau A, . Success and failure of primary medical, nonoperative management in breast cancer. Ann Surg Oncol 2011;18:2166–72.
  • Guth U, Huang DJ, Schotzau A, Zanetti-Dallenbach R, Holzgreve W, Bitzer J, . Target and reality of adjuvant endocrine therapy in postmenopausal patients with invasive breast cancer. Br J Cancer 2008;99:428–33.
  • Guth U, Myrick ME, Kilic N, Eppenberger-Castori S, Schmid SM. Compliance and persistence of endocrine adjuvant breast cancer therapy. Breast Cancer Res Treat 2012;131:491–9.
  • Bouchardy C, Rapiti E, Blagojevic S, Vlastos AT, Vlastos G. Older female cancer patients: Importance, causes, and consequences of undertreatment. J Clin Oncol 2007;25:1858–69.
  • Litvak DA, Arora R. Treatment of elderly breast cancer patients in a community hospital setting. Arch Surg 2006;141:985–90; discussion 990.
  • Fennessy M, Bates T, MacRae K, Riley D, Houghton J, Baum M. Late follow-up of a randomized trial of surgery plus tamoxifen versus tamoxifen alone in women aged over 70 years with operable breast cancer. Br J Surg 2004;91: 699–704.
  • Fentiman IS, Christiaens MR, Paridaens R, Van Geel A, Rutgers E, Berner J, . Treatment of operable breast cancer in the elderly: A randomised clinical trial EORTC 10851 comparing tamoxifen alone with modified radical mastectomy. Eur J Cancer 2003;39:309–16.
  • Mustacchi G, Ceccherini R, Milani S, Pluchinotta A, De Matteis A, Maiorino L, . Tamoxifen alone versus adjuvant tamoxifen for operable breast cancer of the elderly: Long-term results of the phase III randomized controlled multicenter GRETA trial. Ann Oncol 2003;14:414–20.
  • Yellen SB, Cella DF, Leslie WT. Age and clinical decision making in oncology patients. J Natl Cancer Inst 1994;86: 1766–70.
  • Downey L, Livingston R, Stopeck A. Diagnosing and treating breast cancer in elderly women: A call for improved understanding. J Amer Ger Soc 2007;55:1636–44.
  • Ramirez AJ, Westcombe AM, Burgess CC, Sutton S, Littlejohns P, Richards MA. Factors predicting delayed presentation of symptomatic breast cancer: A systematic review. Lancet 1999;353:1127–31.
  • Steinhauser KE, Christakis NA, Clipp EC, McNeilly M, McIntyre L, Tulsky JA. Factors considered important at the end of life by patients, family, physicians, and other care providers. JAMA 2000;284:2476–82.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.