1,107
Views
14
CrossRef citations to date
0
Altmetric
Colorectal cancer

The expression of CYP2W1 in colorectal primary tumors, corresponding lymph node metastases and liver metastases

, , , , , & show all
Pages 885-891 | Received 07 Oct 2013, Accepted 18 Jan 2014, Published online: 13 Mar 2014

References

  • Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61:69–90.
  • Sjovall A, Jarv V, Blomqvist L, Singnomklao T, Cedermark B, Glimelius B, et al. The potential for improved outcome in patients with hepatic metastases from colon cancer: A population-based study. Eur J Surg Oncol 2004;30:834–41.
  • Maringe C, Walters S, Rachet B, Butler J, Fields T, Finan P, et al. Stage at diagnosis and colorectal cancer survival in six high-income countries: A population-based study of patients diagnosed during 2000–2007. Acta Oncol 2013;52:919–32.
  • National follow up colon cancer 2011. [cited 2013 Aug 19]. Available from: www.cancercentrum.se/Global/Diagnoser/kolorektal/rapporter/colon2011.pdf.
  • National follow-up rectal cancer 2013 [cited 2013 Aug 19]. Available from: www.cancercentrum.se/Global/Diagnoser/kolorektal/rapporter/rekti2011_120629.pdf.
  • Siegel R, DeSantis C, Virgo K, Stein K, Mariotto A, Smith T, et al. Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin 2012;62:220–41.
  • Mancini R, Ettorre G, Vennarecci G, Sperduti I, Garufi C, Esposito A, et al. Personal experience on treatment of colorectal liver metastases: A multidisciplinary approach. J Exp Clin Cancer Res 2003;22(4 Suppl):213–7.
  • Norstein J, Silen W. Natural history of liver metastases from colorectal carcinoma. J Gastrointest Surg 1997;1:398–407.
  • Kopetz S, Chang GJ, Overman MJ, Eng C, Sargent DJ, Larson DW, et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 2009;27:3677–83.
  • Abdalla EK, Adam R, Bilchik AJ, Jaeck D, Vauthey JN, Mahvi D. Improving resectability of hepatic colorectal metastases: Expert consensus statement. Ann Surg Oncol 2006; 13:1271–80.
  • Morris EJ, Forman D, Thomas JD, Quirke P, Taylor EF, Fairley L, et al. Surgical management and outcomes of colorectal cancer liver metastases. Br J Surg 2010;97: 1110–8.
  • Kanas GP, Taylor A, Primrose JN, Langeberg WJ, Kelsh MA, Mowat FS, et al. Survival after liver resection in metastatic colorectal cancer: Review and meta-analysis of prognostic factors. Clin Epidemiol 2012;4:283–301.
  • Edler D, Stenstedt K, Ohrling K, Hallstrom M, Karlgren M, Ingelman-Sundberg M, et al. The expression of the novel CYP2W1 enzyme is an independent prognostic factor in colorectal cancer – a pilot study. Eur J Cancer 2009;45: 705–12.
  • Stenstedt K, Hallstrom M, Johansson I, Ingelman-Sundberg M, Ragnhammar P, Edler D. The expression of CYP2W1: A prognostic marker in colon cancer. Anticancer Res 2012;32: 3869–74.
  • Karlgren M, Gomez A, Stark K, Svard J, Rodriguez-Antona C, Oliw E, et al. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. Biochem Biophys Res Commun 2006;341:451–8.
  • Wu ZL, Sohl CD, Shimada T, Guengerich FP. Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1. Mol Pharmacol 2006; 69:2007–14.
  • Gomez A, Karlgren M, Edler D, Bernal ML, Mkrtchian S, Ingelman-Sundberg M. Expression of CYP2W1 in colon tumors: Regulation by gene methylation. Pharmacogenomics 2007;8:1315–25.
  • Nishida CR, Lee M, de Montellano PR. Efficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1. Mol Pharmacol 2010;78:497–502.
  • Xiao Y, Guengerich FP. Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids. J Lipid Res 2012;53:1610–7.
  • Travica S, Pors K, Loadman PM, Shnyder SD, Johansson I, Alandas MN, et al. Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins. Clin Cancer Res 2013;19:2952–61.
  • Habermann JK, Paulsen U, Roblick UJ, Upender MB, McShane LM, Korn EL, et al. Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis. Genes Chromosomes Cancer 2007;46:10–26.
  • Nambiar PR, Gupta RR, Misra V. An “Omics” based survey of human colon cancer. Mutation research 2010;693:3–18.
  • Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, Antal T, et al. Comparative lesion sequencing provides insights into tumor evolution. Proc Natl Acad Sci U S A 2008;105:4283–8.
  • Ramaswamy S, Ross KN, Lander ES, Golub TR. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003;33:49–54.
  • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759–67.
  • Valastyan S, Weinberg RA. Tumor metastasis: Molecular insights and evolving paradigms. Cell 2011;147: 275–92.
  • Dittmar T, Heyder C, Gloria-Maercker E, Hatzmann W, Zanker KS. Adhesion molecules and chemokines: The navigation system for circulating tumor (stem) cells to metastasize in an organ-specific manner. Clin Exp Metastasis 2008;25: 11–32.
  • Gomez A, Nekvindova J, Travica S, Lee MY, Johansson I, Edler D, et al. Colorectal cancer-specific cytochrome P450 2W1: Intracellular localization, glycosylation, and catalytic activity. Mol Pharmacol 2010;78:1004–11.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.