Treatment of Segmental Defects in Long Bones Using Osteopromotive Membranes and Recombinant Human Bone Morphogenetic Protein-2: An Experimental Study in Rabbits

References

• Baadsgaard K. Defect pseudoarthroses. An experimental study in rabbits. Acta Orthop Scand 1970; 40: 689–695
   Google Scholar
• Bluhm A E, Laskin D M. The effect of polytetrafluoroethylene cylinders on osteogenesis in rat fibular defects: a preliminary study. J Oral Maxillofac Surg 1995; 53: 163–166
   PubMedGoogle Scholar
• Celeste A J, Iannazzi J A, Taylor R C, et al. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 1990; 87: 9843–9847
   PubMed Web of Science ®Google Scholar
• Cook S D, Baffes G C, Wolfe M W, Sampath T K, Rueger D C. Recombinant human bone morphogenetic protein-7 induces healing in a canine long-bone segmental defect model. Clin Orthop 1994; 301: 302–312
   PubMed Web of Science ®Google Scholar
• Cook S D, Wolfe M W, Salkeld S L, Rueger D C. Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. J Bone Joint Surg 1995; 77A: 734–750
   Web of Science ®Google Scholar
• Dahlin C, Linde A, Röckert H. Stimulation of early bone formation by the combination of an osteopromotive membrane technique and hyperbaric oxygen. Scand J Plast Reconstr Surg Hand Surg 1993; 27: 103–108
   PubMed Web of Science ®Google Scholar
• Einhorn T A, Lane J M, Burstein A H, Kopman C R, Vigorita V J. The healing of segmental bone defects induced by demineralized bone matrix. J Bone Joint Surg 1984; 66A: 274–279
   Web of Science ®Google Scholar
• Nielsen Farsø F. Guided bone induction. A method in the treatment of diaphyseal longbone defects. Thesis, Royal Dental College, AarhusDenmark 1992
   Google Scholar
• Friedenstein A J, Piatetzky-Shaprio I I, Petrakova K V. Osteogenesis in transplants of bone marrow cells. J Embryol Exp Morphol 1966; 16: 381–390
   PubMedGoogle Scholar
• Friedenstein A J. Precursor cells of mechanocytes. Int Rev Cytol 1976; 47: 327–359
   PubMed Web of Science ®Google Scholar
• Gerhart T N, Kirker-Head C A, Kriz M J, et al. Healing of segmental femoral defects in sheep using recombinant human bone morphogenetic protein. Clin Orthop 1993; 293: 317–326
   PubMedGoogle Scholar
• Hedner E, Linde A. Bone morphogenetic protein (BMP) implant in rat mandibular defects, covered by osteopromotive membranes. Eur J Oral Sci 1995; 103: 236–241
   PubMed Web of Science ®Google Scholar
• Hedner E, Linde A, Nilsson A. Systemically and locally administered growth hormone stimulates bone healing in combination with osteopromotive membranes. An experimental study in rats. J Bone Miner Res 1996; 11: 1952–1960
   PubMed Web of Science ®Google Scholar
• Lee S C, Shea M, Battle M A, et al. Healing of large segmental defects in rat femurs is aided by rhBMP-2 in PLGA matrix. J Biomed Mater Res 1994; 28: 149–156
   Google Scholar
• Linde A, Alberius P, Dahlin C, Bjurstam K, Sundin Y. Osteopromotion: a soft-tissue exclusion principle using a membrane for bone healing and bone neogenesis. J Periodontol 1993; 64: 1116–1128
   PubMed Web of Science ®Google Scholar
• Linde A, Thorén C, Dahlin C, Sandberg E. Creation of new bone by an osteopromotive membrane technique: an experimental study in rats. J Oral Maxillofac Surg 1993; 51: 892–897
   PubMedGoogle Scholar
• Linde A, Hedner E. Recombinant bone morphogenetic protein enhances bone healing, guided by osteopromotive e-PTFE membranes: an experimental study in rats. Calcif Tissue Int 1995; 56: 549–553
   PubMed Web of Science ®Google Scholar
• Nyman R, Magnusson M, Sennerby L, Nyman S, Lundgren D. Membrane-guided bone regeneration. Segmental radius defects studied in the rabbit. Acta Orthop Scand 1995; 66: 169–173
   PubMed Web of Science ®Google Scholar
• Ron E, Schaub R G, Turek T J. US Patent. 5, 171, 579, 1992, Formulations of blood-clot polymer matrix for delivery of osteogenic proteins
   Google Scholar
• Sandberg E, Dahlin C, Linde A. Bone regeneration by the osteopromotion technique using bioabsorbable membranes: an experimental study in rats. J Oral Maxillofac Surg 1993; 51: 1106–1114
   PubMedGoogle Scholar
• Tiedeman J J, Connolly J F, Strates B S, Lippiello L. Treatment of nonunion by percutaneous injection of bone marrow and demineralized bone matrix. Clin Orthop 1991; 268: 294–302
   Google Scholar
• Wang E A, Rosen V, D'Alessandro J S., et al. Recombinant bone morphogenetic protein induces bone formation. Proc Natl Acad Sci USA 1990; 87: 2220–2224
   PubMed Web of Science ®Google Scholar
• Wozney J M, Rosen V, Celeste A J, et al. Novel regulators of bone formation: Molecular clones and activities. Science 1988; 242: 1528–1534
   PubMed Web of Science ®Google Scholar
• Yasko A W, Lane J M, Fellinger E J, Rosen V, Wozney J M, Wang E A. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological and biomechanical study in rats. J Bone Joint Surg 1992; 74A: 659–671
   Web of Science ®Google Scholar
• Zellin G, Gritli-Linde A, Linde A. Healing of mandibular defects with different biodegradable and non-biodegradable membranes. An experimental study in rats. Biomaterials 1995; 16: 601–609
   PubMed Web of Science ®Google Scholar
• Zellin G, Linde A. Effects of different osteopromotive membrane porosities on experimental bone neogenesis in rats. Biomaterials 1996; 17: 695–702
   PubMed Web of Science ®Google Scholar
• Zellin G, Linde A. Importance of delivery systems for growth-stimulatory factors in combination with osteopromotive membranes. An experimental study using rhBMP-2 in rat mandibular defects. J Biomed Mater Res 1997; 35, in press
   PubMedGoogle Scholar
• Özkaynak E, Rueger D C, Drier E A, et al. OP-1 cDNA encodes an osteogenic protein in the TGF-β family. EMBO J 1990; 9: 2085–2093
   PubMed Web of Science ®Google Scholar