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Research Article

Inactivation of SPARC enhances high-fat diet-induced obesity in mice

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Pages 99-108 | Received 19 Nov 2009, Accepted 04 Apr 2010, Published online: 08 Jul 2010

REFERENCES

  • Bornstein, P., and Sage, E.H. (2002). Matricellular proteins: Extracellular modulators of cell function. Curr. Opin. Cell Biol. 14(5):608–616.
  • Bradshaw, A.D., and Sage, E.H. (2001). SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J. Clin. Invest. 107(9):1049–1054.
  • Bradshaw, A.D., Graves, D.C., Motamed, K., and Sage, E.H. (2003). SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. Proc. Natl Acad. Sci. U.S.A. 100(10):6045–6050.
  • Delany, A.M., Kalajzic, I., Bradshaw, A.D., Sage, E.H., and Canalis, E. (2003). Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology 144(6):2588–2596.
  • Tartare-Deckert, S., Chavey, C., Monthouel, M.N., Gautier, N., and Van Obberghen, E. (2001). The matricellular protein SPARC/osteonectin as a newly identified factor up-regulated in obesity. J. Biol. Chem. 276(25):22231–22237.
  • Chen, H.C., and Farese, R.V., Jr. (2002). Determination of adipocyte size by computer image analysis. J. Lipid Res. 43(6):986–989.
  • Woessner, J.F., Jr. (1961). The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch. Biochem. Biophys. 93:440–447.
  • Junqueira, L.C., Bignolas, G., and Brentani, R.R. (1979). Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem. J. 11(4):447–455.
  • Nie, J., and Sage, E.H. (2009). SPARC inhibits adipogenesis by its enhancement of beta-catenin signaling. J. Biol. Chem. 284(2):1279–1290.
  • Karsenty, G. (2006). Convergence between bone and energy homeostases: Leptin regulation of bone mass. Cell Metab. 4(5):341–348.
  • Zhao, L.J., Jiang, H., Papasian, C.J., Maulik, D., Drees, B., Hamilton, J., and Deng, H.W. (2008). Correlation of obesity and osteoporosis: Effect of fat mass on the determination of osteoporosis. J. Bone Miner. Res. 23(1):17–29.
  • Delany, A.M., Amling, M., Priemel, M., Howe, C., Baron, R., and Canalis, E. (2000). Osteopenia and decreased bone formation in osteonectin-deficient mice. J. Clin. Invest. 105(7):915–923.
  • Machado do Reis, L., Kessler, C.B., Adams, D.J., Lorenzo, J., Jorgetti, V., and Delany, A.M. (2008). Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice. Bone 43(2):264–273.
  • Glatt, V., Canalis, E., Stadmeyer, L., and Bouxsein, M.L. (2007). Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J. Bone Miner. Res. 22(8):1197–1207.
  • Lijnen, H.R., Maquoi, E., Demeulemeester, D., Van Hoef, B., and Collen, D. (2002). Modulation of fibrinolytic and gelatinolytic activity during adipose tissue development in a mouse model of nutritionally induced obesity. Thromb. Haemost. 88(2):345–353.
  • Aratani, Y., and Kitagawa, Y. (1988). Enhanced synthesis and secretion of type IV collagen and entactin during adipose conversion of 3T3-L1 cells and production of unorthodox laminin complex. J. Biol. Chem. 263(31):16163–16169.
  • Chun, T.H., Hotary, K.B., Sabeh, F., Saltiel, A.R., Allen, E.D., and Weiss, S.J. (2006). A pericellular collagenase directs the 3‐dimensional development of white adipose tissue. Cell 125(3):577–591.
  • Francki, A., Bradshaw, A.D., Bassuk, J.A., Howe, C.C., Couser, W.G., and Sage, E.H. (1999). SPARC regulates the expression of collagen type I and transforming growth factor-beta1 in mesangial cells. J. Biol. Chem. 274(45):32145–32152.
  • Sweat, F., Puchtler, H., and Rosenthal, S.I. (1964). Sirius red F3ba as a stain for connective tissue. Arch. Pathol. 78:69–72.
  • Bradshaw, A.D., Puolakkainen, P., Dasgupta, J., Davidson, J.M., Wight, T.N., and Helene Sage, E. (2003). SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J. Invest. Dermatol. 120(6):949–955.
  • Tang, Q.Q., Otto, T.C., and Lane, M.D. (2003). Mitotic clonal expansion: A synchronous process required for adipogenesis. Proc. Natl Acad. Sci. U.S.A. 100(1):44–49.
  • Bradshaw, A.D., Baicu, C.F., Rentz, T.J., Van Laer, A.O., Boggs, J., Lacy, J.M., and Zile, M.R. (2009). Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: Role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing. Circulation 119(2):269–280.
  • Yan, Q., Blake, D., Clark, J.I., and Sage, E.H. (2003). Expression of the matricellular protein SPARC in murine lens: SPARC is necessary for the structural integrity of the capsular basement membrane. J. Histochem. Cytochem. 51(4):503–511.
  • Golembieski, W.A., Thomas, S.L., Schultz, C.R., Yunker, C.K., McClung, H.M., Lemke, N., Cazacu, S., Barker, T., Sage, E.H., Brodie, C., and Rempel, S.A. (2008). HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion. Glia 56(10):1061–1075.
  • Au, E., Richter, M.W., Vincent, A.J., Tetzlaff, W., Aebersold, R., Sage, E.H., and Roskams, A.J. (2007). SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair. J. Neurosci. 27(27):7208–7221.
  • Ikemoto, M., Takita, M., Imamura, T., and Inoue, K. (2000). Increased sensitivity to the stimulant effects of morphine conferred by anti-adhesive glycoprotein SPARC in amygdala. Nat. Med. 6(8):910–915.
  • Handjieva-Darlenska, T., and Boyadjieva, N. (2009). The effect of high-fat diet on plasma ghrelin and leptin levels in rats. J. Physiol. Biochem. 65(2):157–164.
  • Kim, J.Y., van de Wall, E., Laplante, M., Azzara, A., Trujillo, M.E., Hofmann, S.M., Schraw, T., Durand, J.L., Li, H., Li, G., Jelicks, L.A., Mehler, M.F., Hui, D.Y., Deshaies, Y., Shulman, G.I., Schwartz, G.J., and Scherer, P.E. (2007). Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117(9):2621–2637.
  • Sage, H., Vernon, R.B., Funk, S.E., Everitt, E.A., and Angello, J. (1989). SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix. J. Cell Biol. 109(1):341–356.
  • Schiemann, B.J., Neil, J.R., and Schiemann, W.P. (2003). SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system. Mol. Biol. Cell 14(10):3977–3988.
  • Funk, S.E., and Sage, E.H. (1991). The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells. Proc. Natl Acad. Sci. U.S.A. 88(7):2648–2652.
  • Bradshaw, A.D., Francki, A., Motamed, K., Howe, C., and Sage, E.H. (1999). Primary mesenchymal cells isolated from SPARC-null mice exhibit altered morphology and rates of proliferation. Mol. Biol. Cell 10(5):1569–1579.
  • Said, N., Frierson, H.F., Jr., Chernauskas, D., Conaway, M., Motamed, K., and Theodorescu, D. (2009). The role of SPARC in the TRAMP model of prostate carcinogenesis and progression. Oncogene 28(39):3487–3498.
  • Motamed, K., Funk, S.E., Koyama, H., Ross, R., Raines, E.W., and Sage, E.H. (2002). Inhibition of PDGF-stimulated and matrix-mediated proliferation of human vascular smooth muscle cells by SPARC is independent of changes in cell shape or cyclin-dependent kinase inhibitors. J. Cell Biochem. 84(4):759–771.
  • Sage, H., Vernon, R.B., Decker, J., Funk, S., and Iruela-Arispe, M.L. (1989). Distribution of the calcium-binding protein SPARC in tissues of embryonic and adult mice. J. Histochem. Cytochem. 37(6):819–829.
  • Reed, M.J., Vernon, R.B., Abrass, I.B., and Sage, E.H. (1994). TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors. J. Cell. Physiol. 158(1):169–179.
  • Kos, K., Wong, S., Tan, B., Gummesson, A., Jernas, M., Franck, N., Kerrigan, D., Nystrom, F.H., Carlsson, L.M., Randeva, H.S., Pinkney, J.H., and Wilding, J.P. (2009). Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose. Diabetes 58(8):1780–1788.
  • Neri, M., Descalzi-Cancedda, F., and Cancedda, R. (1992). Heat-shock response in cultured chick embryo chondrocytes. Osteonectin is a secreted heat-shock protein. Eur. J. Biochem. 205(2):569–574.
  • Reid, I.R. (2008). Relationships between fat and bone. Osteoporos. Int. 19(5):595–606.
  • Robling, A.G., and Turner, C.H. (2002). Mechanotransduction in bone: Genetic effects on mechanosensitivity in mice. Bone 31(5):562–569.
  • Bradshaw, A.D., Bassuk, J.A., Francki, A., and Sage, E.H. (2000). Expression and purification of recombinant human SPARC produced by baculovirus. Mol. Cell Biol. Res. Commun. 3(6):345–351.

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