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Research Article

Enforced Bipedal Downhill Running Induces Achilles Tendinosis in Rats

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Pages 466-471 | Received 25 Sep 2010, Accepted 08 Feb 2011, Published online: 18 May 2011

REFERENCES

  • Kettunen, J.A., Kujala, U.M., Kaprio, J., and Sarna, S. (2006). Health of master track and field athletes: A 16-year follow-up study. Clin. J. Sport. Med. 16:142–148.
  • Kujala, U.M., Sarna, S., and Kaprio, J. (2005). Cumulative incidence of Achilles tendon rupture and tendinopathy in male former elite athletes. Clin. J. Sport. Med. 15:133–135.
  • Silbernagel, K.G., Thomee, R., Eriksson, B.L., and Karlsson, J. (2007). Continued sports activity, using a pain-monitoring model, during rehabilitation in patients with Achilles tendinopathy – A randomized controlled study. Am. J. Sports. Med. 35(6):897–906.
  • Khan, K.M., Bonar, F., Desmond, P.M., Cook, J.L., Young, D.A., Visentini, P.J., Fehrmann, M.W., Kiss, Z.S., O'Brien, P.A., Harcourt, P.R., Dowling, R.J., O'Sullivan, R.M., Crichton, K.J., Tress, B.M., and Wark, J.D. (1996). Patellar tendinosis (jumper's knee): Findings at histopathologic examination, US and MR imaging. Radiology 200:821–827.
  • Riley, G. (2004). The pathogenesis of tendinopathy. A molecular perspective. Rheumatology 43:131–142.
  • Archambault, J.M., and Banes, A.J. (2005). Research methodology and animal modelling in tendinopathy. In Tendon Injuries, Basic Science and Clinical Medicine, N. Maffulli, P. Renström, and W.B. Leadbetter ( eds.) pp. 281–282. London: Springer.
  • Fedorczky, J.M., Barr, A.E., Rani, S., Gao, H.G., Amin, M., Amin, S., Litvin, J., and Barbe, M.F. (2010). Exposure-dependent increases in 1L-1β, Substance P, CTGF, and tendinosis in flexor digotorum tendons with upper extremity repetitive strain injury. J. Orthop. Res. 28:298–207.
  • Glazebrook, M.A., Wright, J.R., Langman, M., Stanish, W.D., and Lee, J.M. (2008). Histological analysis of Achilles tendons in an overuse rat model. J. Orthop. Res. 26:840–846.
  • Messner, K., Wei, Y., Andersson, B., Gillquist, J., and Räsänen, T. (1999). Rat model of Achilles tendon disorder. A pilot study. Cells Tissues Organs. 165:30–39.
  • Nakama, L.H., King, K.B., Abrahamsson, S., and Rempel, D.M. (2005). Evidence of tendon microtears due to cyclical loading in an in vivo tendinopathy model. J. Orthop. Res. 23(5):1199–1205.
  • Soslowsky, L.J., Thomopoulos, M.S., Tun, S., Flanagan, C.L., Keefer, C.C., Mastaw, J., and Carpenter, J.E. (2000). Overuse activity injures the supraspinatus tendon in an animal model: A histologic and biomechanical study. J. Shoulder Elbow Surg. 9:79–84.
  • Huang, T.F., Perry, S.M., and Soslowsky, L.J. (2004). The effect of overuse activity on Achilles tendon in an animal model: A biomechanical study. Ann. Biomed. Eng. 32(3):336–341.
  • Woo, S.L.Y., Orlando, C.A., Camp, J.F., and Akeson, W.H. (1986). Effects of postmortem storage by freezing on ligament tensile ligament behavior. J Biomech. 19(5):399–404.
  • Ng, G.Y.F., Oakes, B.W., McLean, I.D., Deacon, O.W., and Lampard, D. (1996). The long-term biomechanical and viscoelastic performance of repairing anterior cruciate ligament after hemitransection injury in a goat model. Am. J. Sports Med. 24(1):109–117.
  • Ng, G.Y.F., Fung, D.T.C., Leung, M.C.P., and Guo, X. (2004). Comparison of single and multiple applications of a therapeutic low energy laser for ligament repair. Lasers Surg. Med. 34(3):285–289.
  • See, E.K.N., Ng, G.Y.F., Ng, C.O.Y., and Fung, D.T.C. (2004). Running exercise improves the strength of partially ruptured tendo-achilles. Br. J. Sports Med. 38(5):597–600.
  • Fung, D.T.C., Ng, G.Y., Leung, M.C.P., and Tay, D.K.C. (2002). Therapeutic low energy laser improves the mechanical strength of repairing medial collateral ligament. Lasers Surg. Med. 31(2):91–96.
  • Ng, C.O.Y., Ng, G.Y.F., See, E.K.N., and Leung, M.C.P. (2003). Therapeutic ultrasound improves strength of Achilles tendon repair in rats. Ultrasound Med. Biol. 9(10):1501–1506.
  • Chan, H.K.F., Fung, D.T.C., and Ng, G.Y.F. (2007). Effects of low-voltage microamperage stimulation on tendon healing in rats. J. Orthop. Sports Phys. Ther. 37(7):399–403.
  • Warden, S.J. (2009). Development and use of animal models to advance tendinopathy research. Front. Biosci. 14:4588–4597.
  • Cook, J.L., Kiss, Z.S., Khan, K.M., Purdam, C.R., and Webster, K.E. (2004). Anthropometry, physical performance, and ultrasound patellar tendon abnormality in elite junior basketball players: A cross-sectional study. Br. J. Sports Med. 38:206–209.
  • Mahieu, N.N., Witvrouw, E., Stevens, V., Van Tiggelen, D., and Roget, P. (2006). Intrinsic risk factors for the development of Achilles tendon overuse injury: A prospective study. Am. J. Sports Med. 34:226–235.
  • Mokone, G.G., Schwellnus, M.P., Noakes, T.D., and Collins, M. (2006). The COL5A1 gene and Achilles tendon pathology. Scand J. Med. Sci. Sports. 16:19–26.
  • Witvrouw, E., Bellemans, J., Lysens, R., Danneels, L., and Cambier, D. (2001). Intrinsic risk factors for the development of patellar tendinitis in an athletic population. A two-year prospective study. Am. J. Sports Med. 29:190–195.
  • Reeves, N.D. (2006). Adaptation of the tendon to mechanical usage. J. Musculoskelet. Neuronal. Interact. 6:174–180.
  • Frost, H.M. (1990). Skeletal structural adaptations to mechanical usage (SATMU): 4. Mechanical influences on intact fibrous tissues. Anat. Rec. 226:433–439.
  • Cook, J.L., Feller, J.A., Bonar, S.F., and Khan, K.M. (2004). Abnormal tenocyte morphology is more prevalent than collagen disruption in asymptomatic athletes' patellar tendons. J. Orthop. Res. 22:334–338.

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