Advanced search
Publication Cover
Upsala Journal of Medical Sciences Volume 121, 2016 - Issue 1
Journal homepage
644
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide

Per LissDepartment of Oncology, Radiology and Clinical Immunology, Section of Radiology, University Hospital, Uppsala, Sweden;
,
Peter HansellDepartment of Medical Cell Biology, Section of Integrative Physiology, Uppsala University, Uppsala, Sweden;
,
Angelica FaschingDepartment of Medical Cell Biology, Section of Integrative Physiology, Uppsala University, Uppsala, Sweden;
&
Fredrik PalmDepartment of Medical Cell Biology, Section of Integrative Physiology, Uppsala University, Uppsala, Sweden; ;Department of Science and Health, Division of Drug Research, University of Linköping, Linköping, SwedenCorrespondence[email protected]
Pages 12-16 | Received 15 Nov 2015, Accepted 15 Jan 2016, Published online: 02 Mar 2016

References

  • Hou SH, Bushinsky DA, Wish JB, Cohen JJ. Hospital-acquired renal insufficiency. A prospective study. Am J Med. 1983;63:243–8.
  • Rihal CS, Textor SC, Grill DE, Berger PB, Ting HH, Best PJ, et al. Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation. 2002;105:2259–64.
  • Brezis M, Rosen S. Hypoxia of the renal medulla - its implication for disease. N Engl J Med. 1995;332:647–55.
  • Persson PB, Hansell P, Liss P. Pathophysiology of contrast medium-induced nephropathy. Kidney Int. 2005;68:14–22.
  • Welch WJ, Baumgartl H, Lubbers D, Wilcox CS. Nephron pO2 and renal oxygen usage in the hypertensive rat kidney. Kidney Int. 2001;59:230–7.
  • Welch WJ, Baumgartl H, Lubbers D, Wilcox CS. Renal oxygenation defects in the spontaneously hypertensive rat: role of AT1 receptors. Kidney Int. 2003;63:202–8.
  • Palm F, Cederberg J, Hansell P, Liss P, Carlsson PO. Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension. Diabetologia. 2003;46:1153–60.
  • Thomsen HS, Morcos SK. Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol. 2003;76:513–18.
  • Liss P, Persson PB, Hansell P, Lagerqvist B. Renal failure in 57 925 patients undergoing coronary procedures using iso-osmolar or low-osmolar contrast media. Kidney Int. 2006;70:1811–17.
  • Fahling M. Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia. Acta Physiol (Oxf). 2009;195:205–30.
  • Koivisto A, Matthias A, Bronnikov G, Nedergaard J. Kinetics of the inhibition of mitochondrial respiration by NO. FEBS Lett. 1997;417:75–80.
  • Koivisto A, Pittner J, Froelich M, Persson AE. Oxygen-dependent inhibition of respiration in isolated renal tubules by nitric oxide. Kidney Int. 1999;55:2368–75.
  • Palm F, Buerk DG, Carlsson PO, Hansell P, Liss P. Reduced nitric oxide concentration in the renal cortex of streptozotocin-induced diabetic rats: effects on renal oxygenation and microcirculation. Diabetes. 2005;54:3282–7.
  • Hawksworth GM. Isolation and culture of human renal cortical cells with characteristics of proximal tubules. Methods Mol Med. 2005;107:283–90.
  • Korner A, Eklof AC, Celsi G, Aperia A. Increased renal metabolism in diabetes. Mechanism and functional implications. Diabetes. 1994;43:629–33.
  • Cleeter MW, Cooper JM, Darley-Usmar VM, Moncada S, Schapira AH. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett. 1994;345:50–4.
  • Liss P, Nygren A, Olsson U, Ulfendahl HR, Erikson U. Effects of contrast media and mannitol on renal medullary blood flow and red cell aggregation in the rat kidney. Kidney Int. 1996;49:1268–75.
  • Liss P, Nygren A, Erikson U, Ulfendahl HR. Injection of low and iso-osmolar contrast medium decreases oxygen tension in the renal medulla. Kidney Int. 1998;53:698–702.
  • Palm F, Carlsson P-O, Hansell P, Hellberg O, Nygren A, Liss P. Altered response in renal blood flow and oxygen tension to contrast media in diabetic rats. Acta Radiol. 2003;44:347–53.
  • Palm F, Carlsson PO, Fasching A, Hansell P, Liss P. Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism. Adv Exp Med Biol. 2006;578:161–6.
  • Deng A, Miracle CM, Suarez JM, Lortie M, Satriano J, Thomson SC, et al. Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II. Kidney Int. 2005;68:723–30.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.