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Scandinavian Journal of Rheumatology Volume 13, 1984 - Issue 2
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Original Article

Controlled Release lndomethacin (Indotard®): Clinical Trial in Patients with Rheumatoid Arthritis

L. Ejstrup Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
,
S. Freisleben Sørensen Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
,
C. Hellesen Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
,
A. G. Jurik Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
,
O. Mune Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
&
A. Skinhøj Departments of Rheumatology, University Hospital, Odense, County Hospital, Esbjerg, Glostrup Hospital, University of Copenhagen, the Rheumatism Research Unit of Århus University, County Hospital, Kolding and Controlled Release Division, A/S Alfred Benzon, Denmark
Pages 147-150 | Received 28 Dec 1982, Published online: 12 Jul 2009

References

  • Bechgaard H. Design of controlled release products as adapted to gastrointestinal pH and transit time. Optimization of drug delivery, H. Bundgaard, A. B. Hansen, H. Kofod. Munksgaard, Copenhagen 1982; 67–77
  • Bechgaard H., Chasseaud R. R., Brodie L. F., Houmøller P., Hunter J. A., Siklos P., Taylor T. Bioavailability of indomethacin from two multiple-units controlled-release formulations. Eur J Clin Pharmacol 1982; 21: 511
  • Boardman P. L., Dudley Hart F. Side effects of indomethacin. Ann Rheum Dis 1967; 26: 127
  • Helleberg L. Clinical pharmacokinetics of indomethacin. Clin Pharmacokinet 1981; 6: 245
  • Huskisson E. C., Taylor R. T., Burston D., Chuter P. J., Dudley Hart F. Evening indomethacin in the treatment of rheumatoid arthritis. Ann Rheum Dis 1970; 29: 393
  • Rothermich N. O. An extended study of indomethacin. JAMA 1966; 195: 531
  • Hart A. R., Rhymem C. B., Daurio C. A double-blind trial comparing indomethacin sustained release capsules (Indocid-R) with indomethacin capsules in patients with rheumatoid arthritis. Rheumatol Rehabil 1982; 21: 101
  • Statistical evaluation of clinical trials with Acetard. Spadille 1978, Internal Report, A/S Alfred Benzon

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