The Pathogenesis and Consequence of Non Steroidal Anti-Inflammatory Drug Induced Small Intestinal Inflammation in Man

References

• Kent T. H., Cardelli R. M., Stamler F. W. Small intestinal ulcers and intestinal flora in rats given indomethacin. Am J Pathol 1969; 54: 237–245
   PubMed Web of Science ®Google Scholar
• Brodie D. A., Cook P. G., Bauer BJ, et al. Idomethacin-induced intestinal lesions in the rat. Toxicol Appl Pharmacol 1970; 17: 615–624
   PubMed Web of Science ®Google Scholar
• Wax J., Clinger W. A., Vamer P, et al. Relationship of the enterohepatic cycle to ulcerogenesis in the rat small bowel with flufenamic acid. Gastroenterology 1970; 58: 772–780
   PubMed Web of Science ®Google Scholar
• Fang W-F, Broughton A., Jacobson E. D. Indomethacin-induced intestinal inflammation. Am J Dig Dis 1977; 22: 749–760
   PubMedGoogle Scholar
• Whittle B. J. R. Temporal relationship between cyclo-oxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat. Gastroenterology 1981; 80: 94–98
   PubMed Web of Science ®Google Scholar
• Whittle B. J. R., Salmon J. A. Biosynthesis of prostacyclin and prostaglandin E2 in gastrointestinal tissue. Intestinal secretion. Turnburg L.A. Oxprint Ltd. 1983; 69–73
   Google Scholar
• Robert A. Effects of prostaglandins on the stomach and the intestine. Prostaglandins 1974; 6: 523–532
   PubMedGoogle Scholar
• Robert A. Cytoprotection by prostaglandins. Gastroenterology 1975; 77: 761–767
   Google Scholar
• Satoh H., Guth P. H., Grossman M. I. Role of bacteria in gastric ulceration produced by indomethacin in the rat: cytoprotective action of antibiotics. Gastroenterology 1983; 84: 483–489
   PubMed Web of Science ®Google Scholar
• Robert A., Asano T. Resistance of germ free rats to indomethacin-induced intestinal lesions. Prostaglandins 1977; 14: 331–341
   Google Scholar
• Miller T. A. Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms. Am J Physiol 1983; 245: 6601–6623
   Google Scholar
• Kendall M. J., Hawkins C. F. Xylose test; effect of aspirin and indomethacin. Br Med J 1971; i: 553–535
   Google Scholar
• Dyer N. H., Kendall M. J., Hawkins C. F. Malabsorption in rheumatoid arthritis. Ann Rheum Dis 1971; 30: 626–630
   Google Scholar
• Bjarnason I., Williams P., So A, et al. Intestinal permeability and inflammation in rheumatoid arthritis: effects of non-steroidal anti-inflammatory drugs. Lancet 1984; ii: 1171–1174
   Google Scholar
• Bjarnason I., Peters T. J., Levi A. J. Intestinal permeability: clinical correlates. Dig Dis 1986; 4: 83–92
   PubMedGoogle Scholar
• Menzies I. Transmucosal passage of inert molecules in health and disease. Intestinal absorption and secretion. Falk symposium 36, E. Skadhauge, K. Heintze. Lancaster MTP Press. 1984; 527–543
   Google Scholar
• Maxton D., Bjarnason I., Reynolds AP, et al. Lactulose, “CrEDTA, L-rhamnose and polyethyleneglycol 400 as probe markers for assessment in vivo of human intestinal permeability. 1986; 71: 71–80
   Google Scholar
• Bjarnason I., Smethurst P., Levi A. J., Peters T. J. Intestinal permeability to “CrEDTA in rats with experimentally induced enteropathy. Gut 1985; 26: 579–585
   PubMed Web of Science ®Google Scholar
• Likabam S. O., Homeida M. M. A., Cooper B. J. Small intestinal permeability in Sudanese subjects: evidence of tropical enteropathy. Trans Royal Soc Trop Med Hyg 1986; 80: 204–207
   Google Scholar
• Bjarnason I., Williams P., Smethurst P., Peters T. J., Levi A. J. The effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine. Gut, (in press).
   Google Scholar
• Simpson L. O. Intestinal permeability. Lancet 1985; i: 218–219
   Google Scholar
• Veall N. Intestinal permeability. Lancet 1985; i: 588
   Google Scholar
• Jenkins R. J., Goodacre R. L., Rooney P. R., Hunt R. H., Bienstock J. Intestinal permeability in inflammatory bowel disease. Gut 1984; 25: A1166
   Google Scholar
• Struthers G. R., Andrews D. J., Gilson R. J. C., Reynolds G. A., Lowbeer T. Intestinal permeability. Lancet 1985; i: 587–588
   Google Scholar
• Juby L. D., Axon A. J. R., Wright V., Winstanley P., Rothwell J. Intestinal permeability and inflammation in rheumatoid arthritis. Br J Rheumatol 1986; 25: 226–227
   Google Scholar
• Hawkey C. J., Rampton D. S. Prostaglandins and the gastrointestinal mucosae: are they important in its function, disease, or Ireatment. Gastroenterology 1985; 89: 1162–1188
   PubMed Web of Science ®Google Scholar
• Bjarnason I., Omorain C., Levi A. J., Peters T. J. The absorption of ''CrEDTA in inflammatory bowel disease. Gastroenterology 1983; 85: 318–322
   PubMed Web of Science ®Google Scholar
• Saverymuttu S. H., Peters A. M., Pepys MB, et al. Quantitative fecal 111Indium labelled leukocytes excretion in the assessment of disease activity in Crohn's disease. Gastroenterology 1983; 85: 1333–1339
   PubMed Web of Science ®Google Scholar
• Saverymuttu S. H., Camilleri M., Rees H., Lavender J. P., Hodgson H. J. F. 111Indium granulocyte scanning comparison with colonoscopy. histology and faecal 111Indium excretion in assessing disease extent and activity in colitis. Gastroenterology 1986; 90: 1121–1128
   PubMed Web of Science ®Google Scholar
• Peters A. M., Danpure H. J., Osman RJ, et al. Clinical experience with 99mTc-hexamethylpropycene-amineoxime for labelling leucocytes and imaging inflammation. Lancet 1986; ii: 996–999
   Google Scholar
• Bjarnason I., Zanelli G., Smith T, et al. Non-steroidal anti-inflammatory drug induced intestinal inflammation in man;. observation on prevalence, rate of recovery, 111indium leukocyte kinetics, radiology and ileal function in relation to patients with inflammatory bowel disease (submitted).
   Google Scholar
• Segal A. W., Isenberg D. A., Hajirousou V, et al. Preliminary evidence for gut involvement in the pathogenesis of rheumatoid arthritis. Br J Rheumatol 1986; 25: 162–166
   PubMedGoogle Scholar
• Rooney P. J., Jenkins R. T., Smith K. M., Coates G. 111indium-labelled polymorphonuclear leucocyte scans in rheumatoid arthritis; an important clinical cause of false positive results. Br J Rheumatol 1986; 25: 167–170
   PubMedGoogle Scholar
• Nagaraj M. S., Sandhu A. S., Cook L. N., Buchino J. J., Groff D. B. Gastrointestinal perforation following indomethacin therapy in very low birth weight infants. J Pediatr Surg 1981; 16: 1003–1007
   PubMed Web of Science ®Google Scholar
• Lang J., Bjarnason I., Levi A. J., Price A. B. Pathology of introgenic ileal strictures due to NSAID's. Gut 1985; 26: A542
   Web of Science ®Google Scholar
• Bjarnason I., Zanelli G., Prouse P., Gumpel M. J., Levi A. J. Complications of NSAID induced intestinal inflammation in man: bleeding and protein loss. Gastroenterology 1986; 90: 1347
   Google Scholar
• Bjarnason I., Smith T., Zanelli G., Gumpel M. J., Levi A. J. Heal function in patients with NSAID induced intestinal inflammation. Gastroenterology 1986; 90: 1347
   Google Scholar