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Scandinavian Journal of Rheumatology Volume 19, 1990 - Issue 1
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Original Article

Influence of Specific Anti-Salmon Calcitonin Antibodies on Biological Effectiveness of Nasal Salmon Calcitonin in Paget's Disease of Bone

J. Y. Reginster Bone Metabolism Unit, University of Liège, Belgium
,
C. Gennari Institute of Medical Semiotics, University of Siena, Italy
,
C. Mautalen Centro de Osteopatías Médicos y Litiasis Renal, Hospital de Clínicas;, Buenos Aires, Argentina
,
R. Deroisy Bone Metabolism Unit, University of Liège, Belgium
,
D. Denis Bone Metabolism Unit, University of Liège, Belgium
,
M. P. Lecart Bone Metabolism Unit, University of Liège, Belgium
,
J. L. Vandalem Bone Metabolism Unit, University of Liège, Belgium
,
J. Collette Bone Metabolism Unit, University of Liège, Belgium
&
P. Franchimont Bone Metabolism Unit, University of Liège, Belgium
 show all
Pages 83-86 | Received 30 Jan 1989, Published online: 12 Jul 2009

References

  • Niall H D, Keutmann H T, Copp D H, Potts J T. Amino acid sequence of salmon ultimobranchial calcitonin. Proc Natl Acad Sci 1969; 64: 771–8
  • Hosking D J, Denton L B, Cadge B, Martin T J. Functional significance of antibody formation after long-term salmon calcitonin therapy. Clin Endocrin 1979; 10: 243–52
  • Singer F R, Aldred J C, Neer R M, Krane S M, Potts J T, Bloch K J. An evaluation of antibodies and clinical resistance to salmon calcitonin. J Clin Invest 1972; 51: 2331–8
  • Reginster J Y, Franchimont P. Side effect of synthetic salmon calcitonin given by intranasal spray compared with intramuscular injection. Clin Exp Rheum 1985; 3: 155–7
  • Reginster J Y, Denis D, Albert A, Deroisy R, Lecart M P, Fontaine M A, Lambelin P, Franchimont P. 1-Year Controlled Randomization Trial of Prevention of Early Postmenopausal Bone Loss by Intranasal Calcitonin. Lancet 1987; ii: 1481–3
  • Trayser K A, Seligson D. A new kinetic method for the enzyme analysis suitable for automation. Clin Chem 1969; 15: 452
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  • Reginster J Y, Jeugmans-Huynen A M, Albert A, Denis D, Franchimont P. One year's treatment of Paget's disease of bone by synthetic salmon calcitonin as a nasal spray. J Bone Min Res 1988; 3: 249–52
  • Reginster J Y, Denis D, Albert A, Franchimont P. Assessment of the biological effectiveness of nasal synthetic salmon calcitonin (SSCT) by comparison with intramuscular (i.m.) or placebo injection in normal subjects. Bone and Mineral 1987; 2: 133–40
  • Singer F R, Fredericks R S, Minkin C. Salmon calcitonin therapy for Paget's disease of bone. The problem of acquired resistance. Arthritis Rheum 1980; 23: 1148–53
  • Muff R, Levy F, Dotty-Sigrist S, Dambacher M A, Fisher J A. Formation of neutralising antibodies to synthetic salmon calcitonin during treatment of Paget's disease. J Bone Miner Res 1988; 3SI: A96

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