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Original Article

Long-term Evaluation of Penicillamine or Cyclofenil in Systemic Sclerosis: Results from a Two-year Randomized Study

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Pages 238-244 | Received 26 Jun 1991, Accepted 14 Jun 1992, Published online: 12 Jul 2009

References

  • Harris E D, Sioerdsma A. Effect of penicillamine on human collagen and its possible application to treatment of scleroderma. Lancet 1966; 2: 296–9
  • Steen V D, Medsger T A, Rodnan GP. D-penicillamine therapy in progressive systemic sclerosis (scleroderma). A retrospective analysis. Ann Intern Med 1982; 97: 652–9
  • Medsger TA. D-Penicillamine treatment of lung involvement in patients with systemic sclerosis (scleroderma). Arthritis Rheum 1987; 30: 832–4
  • Mason R M, Lineham J D, Phillipson M A, Black CM. Selective inhibition of proteoglycan and hyaluronate synthesis in chondrocyte cultures by cyclofenil diphenol, a non-steroidal weak oestrogen. Biochem J 1984; 223: 401–12
  • Blom-Bülow B, Öberg K, Wollheim FA, et al. Cyclofenil versus placebo in progressive systemic sclerosis. A one-year double-blind crossover study in 27 patients. Acta Med Scand 1981; 210: 419–28
  • Gibson T, Grahame R. Cyclofenil treatment of scleroderma - a controlled study. Br J Rheumatol 1983; 22: 218–23
  • Black C M, Jayson M, White AG. A double-blind comparison of cyclofenil and placebo in scleroderma. Arthritis Rheum 1983; 26: 563
  • Masi A T, Rodnan G P, Medsger TA, et al. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980; 23: 581–90
  • Åkesson A, Forsberg L, Hedenström E, Wollheim F. Ultrasound examination of skin thickness in patients with progressive systemic sclerosis (scleroderma). Acta Radiol [Diagn] (Stockn) 1986; 27: 91–4
  • Åkesson A, Gustafson T, Wollheim F, Brismar J. Esoph-ageal dysfunction and radionuclide transit in progressive systemic sclerosis. Scand J Rheumatol 1987; 16: 291–9
  • Jonson B. A method for determination of pulmonary elastic recoil and resistance at a regulated flow rate. Scand J Clin Lab Invest 1969; 24: 115–25
  • Blom-Biilow B, Jonson B, Brauer K. Lung function in progressive systemic sclerosis is dominated by poorly compliant lungs and stiff airways. Eur J Respir Dis 1985; 66: 1–8
  • Berglund E, Birath G, Biure J, et al. Spirometric studies in normal subjects. I. Forced expirograms in subjects between 7–70 years of age. Acta Med Scand 1963; 173: 185–92
  • Grimby G, Soderholm B. Spirometric studies in normal subjects. 111. Static lung volumes and maximum voluntary ventilation in adults with a note to physical fitness. Acta Med Scand 1963; 173: 199–206
  • Knudson R J, Clark D F, Kennedy T C, Knudson DE. Effects on ageing alone on mechanical properties of the normal adult human lung. J Appl Physiol 1978; 43: 1054–62
  • Jonson B. Pulmonary mechanics in normal men, studied with the flow regular method. Scand J Clin Lab Invest 1970; 25: 363–73
  • De Troyer A, Yernault JC. Inspiratory muscle force in normal subjects and in patients with interstitial lung disease. Thorax 1980; 35: 92–100
  • Geirsson A J, Blom-Biilow B, Pahlm O, Åkesson A. Cardiac involvement in systemic sclerosis. Semin Arthritis Rheum 1989; 19: 110–6
  • Blom-Biilow B, Jonson B, Brauer K. Factors limiting exercise performance in progressive systemic sclerosis. Semin Arthritis Rheum 1983; 13: 174–81
  • Brochner-Mortensen J. A simple method for the determination of glomerular filtration rate. Scand J Clin Lab Invest 1972; 30: 271–4
  • Ristelli J, Niemi S, Trivedi P, Maentausta O, Mowat A P, Ristelli L. Rapid equilibrium radioimmunoassay for the amino-terminal propeptide of human type 111 procollagen. Clin Chem 1988; 34: 715–8
  • Uitto J, Helin P, Rasmussen O, Lorenzen I. Skin collagen in patients with scleroderma: biosynthesis and maturation in vitro, and the effect of Dpenicillamine. Ann Clin Res 1970; 2: 228–34
  • Torres M A, Furst DE. Treatment of generalized systemic sclerosis. Rheumatic Disease Clinics of North America: Scleroderma. WB Saunders. 1990; 217–41
  • Steen V D, Blair S, Medsger TA. The toxicity of D-pen-icillamine in systemic sclerosis. Ann Intern Med 1986; 104: 699–705
  • Steen V D, Medsger TA. Epidemiology and natural history of systemic sclerosis. Rheumatic Disease Clinics of North America: Scleroderma. WB Saunders. 1990; 1–10
  • Herbai G. Treatment of progressive systemic sclerosis with a synthetic weak estrogen: Cyclofenil (sexovid). Acta Med Scand 1974; 196: 537–40
  • Henchl L, Stentoft P, Aggestrup S. The progress of eo-sophageal involvement in progressive systemic sclerosis during D-penicillamine treatment. Scand J Rheumatol 1989; 18: 149–55
  • Peters-Golden M, Wise R A, Schneider P, Hochberg M, Stevens M B, Wigley F. Clinical and demographic predictors of loss of pulmonary function in systemic sclerosis. Medicine 1984; 63: 221–31

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