References
- Scott D L, Dawes P, Tunn T. E. Combination therapy with gold and hydroxychloroquine in rheumatoid arthritis: a prospective, randomised, placebo-controlled study. Br J Rheumatol 1989; 28: 128–33
- Borigini M J, Paulus H E. Combination therapy. Bailliere's Clinical Rheumatology: Innovative Treatment Approaches for Rheumatoid Arthritis, PM Brooks, DE Furst. WB Saunders, London 1995; 689–710
- Furst D E. Clinical pharmacology of combination DMARD therapy in rheumatoid arthritis. J Rheumatol 1996; 23: 86–90
- Paulus H E. Protocol development for combinaton therapy with disease-modifying antirheumatic drugs. Semin Arthritis Rheum 1993; 23: 19–25
- McCarty D J, Carrera G F. Intractable rheumatoid arthritis. Treatment with combined cyclophosphamide azatioprine and hydroxychloroquine. JAMA 1982; 248: 1718–23
- Csuka M, Carrera G F, McCarthy D J. Treatment of intractable rheumatoid arthritis with combined cyclophosphamide azatioprine and hydroxychloroquine. A follow-up study. JAMA 1986; 255: 2315–9
- Taggart A J, Hill J, Astbury C, Dixon J S, Bird H A, Wright V. Sulphasalazine alone or in combination with d-penisillamine in rheumatoid arthritis. Br J Rheumatol 1987; 26: 32–6
- Gibson T, Emery P, Amstrong R D, Crisp A J, Panayi G S. Combined d-penisillamine and chloroquine treatment of rheumatoid arthritis: a comparative study. Br J Rheumatol 1987; 26: 279–84
- Haagsma C J, Van Riel C M, De Rooij D. Combination of methotrexate and sulphasalazine versus methotrexate alone: a randomised open clinical trial in rheumatoid arthritis patient resistant to sulphasalazine therapy. Br J Rheumatol 1994; 33: 1049–55
- Williams H J, Ward J R, Reading J C. Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthitis: a controlled clinical trial. Arthritis Rheum 1992; 35: 259–69
- Willkens R F, Urowitz M B, Stablein D M. Comparison of azathioprine, methotrexate, and the combination of both in the treatment of rheumatoid arthritis: a controlled clinical trial. Arthritis Rheum 1992; 35: 849–56
- Willkens R F, Sharp J E, Stablein D M. Comparison of azathioprine, methotrexate and the combination of both in the treatment of rheumatoid arthritis: A 48 week controlled clinical trial with radiologic outcome assessment. Arthritis Rheum 1995; 38: 1799–1806
- Luthra H S. Midwest Cooperative Rheumatic Disease Study Group: Double-blind study comparing auranofin and hydro-zychloroqine alone and in combination in rheumatoid arthritis (abstract). Arthritis Rheum 1990; S25, Suppl 33
- Faarvang K L, Egsmose C, Kruger P. Hydroxychloroquine and sulphasalazine alone and in combination in rheumatoid arthritis: a randomized double blind trial. Ann Rheum Dis 1993; 52: 711–5
- Tugwell P, Pincus T, Yocum D. Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. N Engl J Med 1995; 333: 137–41
- O'Dell J R, Haire C E, Erikson N. Treatment of rheumatoid arthritis with methotrexate alone, sulphasalazine and hydroxychloroquine, or a combination of all three medications. N Engl J Med 1996; 334: 1287–91
- Clegg D O. for the Hydroxychloroquine-Methotrexate Study Group. Combination hydroxychloroquine and methotrexate in the treatment of rheumatoid arthritis. Arthritis Rheum 1993; 36: S53, (abstract)
- McKenna F, Hopkins R, Hinchcliffe K P. Gold and penicillamine, alone and in combination in active rheumatoid arthritis (abstract). 16th International Congress of Rheumatology 1985, Sydney, Australia
- Bunch T W, O'Duffy J D, Tompkins R B, O'Fallon W M. Controlled trial of hydroxychloroquine and D-penicillamine singly and in combination in the treatment of rheumatoid arthritis. Arthritis Rheum 1984; 27: 267–76
- Van Rijthoven A W, Dijkmans B A, Goei The H S. Comparison of cyclosporine and D-penicillamine for rheumatoid arthritis: A randomized, double blind, multicenter study. J Rheumatol 1991; 18: 815–20
- Felson D T, Anderson J J, Meenan R F. The efficacy and toxicity of combination therapy in rheumatoid arthritis. A metaanalysis. Arthritis Rheum 1994; 37: 1487–91
- Pinals R S, Masi A T, Larsen R A. Preliminary criteria for clinical remission in rheumatoid arthritis. Arthritis Rheum 1981; 24: 1308–15
- Fries J F. Reevaluating the therapeutic approach to rheumatoid arthritis: the “sawtooth” strategy. J Rheumatol 1990; 17: 12–5
- Mottonen T, Paimela L, Ahonen J, Helve T, Hannonen P, Leirisalo-Repo M. Outcome in patients with early rheumatoid arthritis treated according to the “sawtooth” strategy. Arthritis Rheum 1996; 39: 996–1005
- Van der Heijde D MFM, Van't Hof M A, Van Riel P LCM. Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis 1990; 49: 916–20
- Wolfe F. The epidemiology of drug treatment failure in rheumatoid arthritis. Bailliere's Clinical Rheumatology: Innovative treatment approaches for rheumatoid arthritis, PM Brooks, DE Furst. WB Saunders, London 1995; 619–32
- Morgan S L, Baggot J E, Vaughn W H. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med 1994; 121: 833–41
- Cronstein B N, Naime D, Ostad E. The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. J Clin Invest 1993; 92: 2675–82
- Barthel H R, Burmester G R. Specific drugs for a complex disease: can there be a magic bullet against rheumatoid arthritis. Ann Rheum Dis 1995; 54: 948–50