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Journal of Medical Engineering & Technology Volume 14, 1990 - Issue 5
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Original Article

Skin blood flow changes following intradermal bradykinin injections measured by laser Doppler flowmetry: Comparison with weal and flare

T. C. Li Kam Wa Departments of Clinical Pharmacology and, Medical Electronics, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK
,
N. E. Almond Departments of Clinical Pharmacology and, Medical Electronics, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK
,
E. D. Cooke Departments of Clinical Pharmacology and, Medical Electronics, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK
&
P. Turner Departments of Clinical Pharmacology and, Medical Electronics, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK
Pages 190-193 | Published online: 09 Jul 2009

References

  • Stern M. D. In vivo evaluation of microcirculation by coherent light scattering. Nature 1976; 254: 56–58
  • Holloway G. A., Watkins D. W. Laser Doppler measurement of cutaneous blood flow. Journal of Investigative Dermatology 1977; 69: 306–309
  • Bisgaard H., Kristensen J. K. Quantitation of microcirculatory blood flow changes in human cutaneous tissue induced by inflammatory mediators. Journal of Investigative Dermatology 1984; 83: 184–187
  • Serup J., Staberg B. Quantification of weal reactions with laser Doppler flowmetry. Allergy 1985; 40: 233–237
  • Hovell C. J., Beasley C. R. W., Mani R., Holgate S. T. Laser Doppler flowmetry for determining changes in cutaneous blood flow following intradermal injection of histamine. Clinical Allergy 1987; 17: 469–479
  • Greaves M. W., Shuster S. Responses of skin blood vessels to bradykinin, histamine and 5-hydroxytryptamine. Journal of Physiology 1967; 193: 255–267
  • Almond N. E. A fibre-optic laser Doppler flowmeter system and its application to the study of the skin microcirculation in humans. Ph.D. Thesis, University of London. 1987
  • Cook J., Shuster S. Histamine weal formation and absorption in man. British Journal of Pharmacology 1980; 69: 579–585
  • Soter N. A., Lewis R. A., Corey E. J., Austen K. R. Local effects of leukotrienes (LTC4, LTD4, LTE4 and LTB4) in human skin. Journal of Investigative Dermatology 1983; 80: 115–119
  • Li Kam Wa T. C., Almond N. E., Cooke E. D., Turner P. Effect of captopril on skin blood flow following intradermal bradykinin measured by laser Doppler flowmetry. European Journal of Clinical Pharmacology 1989; 37: 471–475
  • Holloway G. A. Cutaneous blood flow responses to injection trauma measured by laser Doppler velocimetry. Journal of Investigative Dermatology 1980; 74: 1–4

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