39
Views
44
CrossRef citations to date
0
Altmetric
Original Article

Computer control systems and pharmacological drug administration: a survey

&
Pages 41-54 | Published online: 09 Jul 2009

References

  • Buell J., Jellipfe R., Kalaba R., Sridhar R. Modern control theory and optimal drug regimens. Mathematical Biostiences 1969; 5: 285–296
  • Smolen V. F., Turrie B. D., Weigand W. A. Drug input optimization: bioavailability-effected time optima! control of multiple, simultaneous pharmacological effects and their interrelationships. Journal of Pharmaceutical Sciences 1972; 61: 1941–1952
  • Bellman R. Topics in pharmacokinetics III: Repeated dosage and impulse control. Mathematical Biostiences 1971; 12: 1–5
  • Sheiner L. B., Rosenberg B., Melmon K. L. Modelling of individual pharmacokinetics for computer-aided drug dosage. Computers and Biomedical Research 1972; 5: 441–459
  • Godfrey K. Compartmental models and their applications. Academic Press, London 1983
  • Vozeh S., Steimer J. L. Feedback control methods for drug dosage optimization. Clinical Pharmacokinetics 1985; 10: 457–476
  • Kruger-Thiemer E. Formal theory of drug dosage regimens. Journal Theoretical Biology 1966; 13: 169–190
  • Hacisaljhzade S. S., Albani C., Toedtli M., Mansour M. A system theoretical approach to drug concentration level problems. Automedica 1986; 6: 285–294
  • Hacisalihzade S. S., Senning M. F., Strobe R., de Figueriedo R. J. P. Optimization of drug administration by a Tauberian approach. IEEE Transactions in Biomedical Engineering 1987; 34: 430–436
  • Pierce J. G., Schumitzky A. Optimal impulsive control of compartment models I: qualitative aspects. Journal of Optimization Theory and Application 1976; 18
  • Pierce J. G., Schumitzky A. Optimal impulsive control of compartment models II: Algorithm. Journal of Optimization Theory and Application 1978; 26
  • Swan G. W. Applications of optimal control theory in biomedicine. Marcel Dekker Inc. 1984
  • Khelfa M., Linkens D. A., Asbury A. J. Nonlinear identification of muscle relaxant dynamics. Proceeding of the IMEKO 3rd Conference on Measurement in Clinical Medicine, Edinburgh, 1986; 257–262
  • Hacisalihzade S. S., Mansour M., Albani C. Optimization of symptomatic therapy in Parkinson's disease. IEEE Transactions in Biomedical Engineering 1989; 37: 363–373
  • Albisser A. M. Devices for the control of diabetes mellitus. IEEE Transactions in Biomedical Engineering 1979; 26: 1308–1320
  • Albisser A. M., Lougheed W., Perlman K., Bahoric A. Non-aggregating insulin solutions for long-term glucose control in experimental and human diabetes. Diabetes 1980; 29: 241–243
  • Albisser A. M., Spencer W. J. Electronics and the diabetic. IEEE Transactions in Biomedical Engineering 1982; 29: 239–248
  • Albisser A. M., Mihic M., Leibel B. S. Intelligent instrumentation for the diabetic: the role of the microprocessor in optimizing insulin therapy. Proceedings of the IMEKO 3rd Conference on Measurement in Clinical Medicine, Edinburgh, 1986; 25–28
  • Perlman K., Ehrlich R. M., Filler R. M., Albisser A. M. Waveform requirements for metabolic normalization with continuous intravenous insulin delivery in man. Diabetes 1981; 30: 710–717
  • Spencer W. J. A review of programmed insulin delivery systems. IEEE Transactions in Biomedical Engineering 1981; 28: 237–257
  • Zimmermann D. M., Froesch E. R. Insulinpumpen. Der Informierte Arzt 1986; 86(1)6–12
  • Rowland M., Sheiner L. B., Steimer J. L. Variability in drug therapy: Description, estimation and control. Raven Press, New York 1985
  • Galliot J., Steimer J. L., Mallet A., Thebault J. J., Bieder A. A priori lithium dosage regimen using population characteristics of pharmacokinetic parameters. Journal of Pharmacokinetics and Biopharmaceutics 1979; 7
  • Sheppard L. C. Guest editorial. Medical Instrumentation 1983; 17
  • Albisser A. M., Schiffrin A., Schultz M., Tiran J., Leibel B. S. Insulin dosage adjustment using manual methods and computer algorithms: a comparative study. Medical and Biological Engineering and Computing 1986; 24: 577
  • Albisser A. M. Insulin therapy: closing the loop with a microprocessor. Methods in Diabetes Research, J Lamer, S Pohl. John Wiley & Sons, New York 1986
  • Koivo A. J. Microprocessor-based controller for pharmacodynamic applications. IEEE Transactions on Automatic Control 1981; 26: 1208–1213
  • Chilcoat R. T. A review of the control of depth of anaesthesia. Transactions of the Institute of Measurement & Control 1980; 2: 38–45
  • Slate J. B. Model-based design of a controller for infusing sodium nitroprusside during post surgical hypertension. Ph D thesis, University of Alabama, Birmingham 1980
  • Jacobs O. L. R., Bullingham R. E. S., Davies W. L., Reasbeck M. P. On-line estimation in the control of post-operative pain. 6th IFAC Symposium on Identification and System Parameter Estimation, Washington, 1982
  • Astrom K. J. Introduction to stochastic control theory. Academic Press, London 1970
  • Tatnall M. L., Morris P., West P. G. Controlled anaesthesia: an approach using patient characteristics identified during uptake. British Journal of Anaesthesia 1981; 53: 1019–1026
  • Salzsieder E., Albretch G., Jutzi E., Fischer U. Estimation of individually adapted control parameters for an artificial beta cell. Biomedica et Biochimica Acta 1984; 43: 585–596
  • Barnikol W. K. R. Panel discussion. Systeman-alyse Biologischer Prozesse, Ebernburg, D Moller. Springer, Berlin 1984
  • Schmidt B. Systemanalyse und modellaufbau. Systemanalyst Biologischer Prozesse, Edemburg, D Moller. Springer, Berlin 1984
  • Schneider B. Die Logik der Modellbildung. Systemanalyse Biologischer Prozesse, Edemburg, D Moller. Springer, Berlin 1984
  • Peck C. C., Brown W. D., Sheiner L. B., Schuster B. G. A microcomputer drug (Theophylline) dosing program which assists and teaches physicians. IEEE, Proceedings of the 4th Annual Symposium on Computer Applications in Medical Care. 1980
  • Sawchuk R. J., Zaske D. E., Cipolle R. J., Wargin W. A., Strate R. G. Kinetic model for gentamicin dosing with the use of individual patient parameters. Clinical Pharmacology and Therapeutics 1977; 21: 362–369
  • Schumitzky A. Adaptive control in drug therapy. Computer Aid to Drug Therapy and Drug Monitoring, Ducrot, et al. North Holland, Amsterdam 1978
  • Kondo K., Sano A., Kikuchi M., Sakurai Y. Adaptive and optimal blood glucose system designed via state space approach. Institute of Measurement & Control Symposium on Control Systems Aspects and Approaches in Clinical Medicine. 1982; 103–106
  • Ackerman E., Rosevear J. W., McGuckin W. F. A mathematical model of the glucose-tolerance test. Physics in Medicine & Biology 1964; 9: 203–213
  • Sano A. Adaptive and optimal schemes for control of blood glucose levels. Biomedical Measurement Informatics and Control 1986; 1
  • Slate J. B., Sheppard L. C., Rideout V. C., Blackstone E. H. A model for design of a blood pressure controller for hypertensive patients. 5th IFAC Symposium on Identification & Systems Parameter Estimation, Darmstadt, 1979
  • Koivo A. J. Automatic continuous-time blood pressure control in dogs by means of hypotensive drug injection. IEEE Transactions on Biomedical Engineering 1980; 27: 574–581
  • Walker B. K., Chia T. L., Stern K. S., Katona P. G. Parameter identification and adaptive control for blood pressure. 6th IFAC Symposium on Ident & Syst Param Estim, Washington, 1982; 1413–1418
  • Millard R. K., Hutton P., Monk C., Pereira E., Prys-Roberts C. Self-tuning control of blood pressure during surgery. 3rd IMEKO Conference on Measurement in Clinical Medicine, Edinburgh, 1986; 173–178
  • Mansour N. E., Linkens D. A. Pole-assignment self-tuning control of blood pressure in postoperative patients: a simulation study. IEE Proceedings PtD 1988; 136: 1–11
  • Mansour N. E., Linkens D. A. A self-tuning Smith predictor applied to the control of blood pressure: simulation studies. Computer Methods and Programs in Biomedicine 1989; 29: 21–29
  • Serna V., Roy R., Kaufman H. Adaptive control of multiple drug infusion. JACC Conference. 1983
  • McInnis B. C., Deng L. Z. Automatic control of blood pressure with multiple drug inputs. Annals of Biomedical Engineering 1985; 13: 217–226
  • Gregory V. L., Katona P. G., Chizeeks H. G. Adaptive multivariate drug delivery: control of arterial pressure and cardiac output in anaesthetized dogs. IEEE Transactions in Biomedical Engineering 1987; 34(8)617–623
  • Linkens D. A., Mansour N. E. Self-tuning control of blood pressure: single variable and multivariable studies. ACASP, Glasgow 1989; 341–346, 89
  • Moller D., Popovic D., Thiele G. Modelling, simulation and parameter estimation of the human cardiovascular system. Advances in Control Systems & Signal Processing, Irmfield, Hartman, 1983; Vol 4
  • Wesseling K. H., Settels J. J., Walstra H. G., Van Esch H. J., Dondfrs J. J. H. Baromodulation as the cause of short term blood pressure variability?. Proceedings of the International Conference on App Phys to Med Biol, G Alberi, Z Bajzer. World Scientific Pub, Singapore 1982
  • Sirisena H. R., Teng F. C. Multivariable pole-zero placement controller. International Journal of Systems Science 1986; 17: 345–352
  • Brown B. H., Asbury A. J., Linkens D. A., Perks R., Anthony M. Closed-loop control of muscle relaxation during surgery. Clinical Physics and Physiological Measurement 1980; 1: 203–210
  • Linkens D. A., Asbury A. J., Rimmer S. J., Menad M. Identification and control of muscle-relaxant anaesthesia. IEE Proceedings Pi D 1982; 129: 136–141
  • Linkens D. A., Menad M., Asbury A. J. Smith predictor and self-tuning control of muscle relaxant drug administration. IEE Proceedings Pt D 1985; 132: 212–218
  • Khelfa M., Linkens D. A., Asbury A. J. Nonlinear identification of muscle relaxant drug dynamics. Biomedical Measurement, Informatics and Control 1988; 2: 130–137
  • Linkens D. A., Denai M., Asbury A. J., McCleod A. D., Gray W. M. Self-tuning PID control of muscle-relaxant drug administration in operating theatres. ACASP, Glasgow 1989; 381–386
  • Cramp D. G., Carson E. R. Intelligent systems and management of the critically ill. 3rd IMEKO Conference on Measurement in Clinical Medicine, Edinburgh, 1986; 133–138
  • Cramp D. G., Carson E. R. Design of an intelligent system for closed-loop control of fluid balance. Biomedical Measurement, Informatics and Control 1986; 1: 49–55
  • Linkens D. A., Mahfouf M. Knowledge-based control for muscle relaxant anaesthesia. 1st 1EAC Symposium on Modelling and Control of Biomedical Systems, Venice, 1988; 185–190
  • Linkens D. A., Greenhow S. G., Asbury A. J., Rob H. M. A GEM-based graphics interface for a knowledge-based on-line advisor in operating theatres. IEE Colloqium on Man-machine interface for 1KBS 1987
  • Linkens D. A., Greenhow S. G., Asbury A. J., Rob H. M. Recent advances in an expert advisor for anaesthesia. BMIS Symposium on Expert Systems in Medicine, London, 1988; 5
  • Chiixoat R. T., Lunn J. N., Mapleson W. W. Computer assistance in the control of depth of anaesthesia. British Journal Anaesthesia 1984; 56: 1417–1437
  • Gray W. M., Asbury A. J. Measurement and control of depth of naesthesia in surgical patients. Proceedings of the 1MEK0 3rd Conference on Measurement in Clinical Medicine, Edinburgh, 1986; 167–172
  • Gorry G. A., Silverman H., Pauker S. G. Capturing clinical expertise: A computer program that considers clinical response to digitalis. American Journal Medicine 1978; 64: 452–460
  • Jelliffe R. W. Open-loop-feedback control of serum drug concentrations: pharmacokinetic approaches to drug therapy. Medical Instrumentation 1983; 17
  • Carson E. R., Cobello C., Finkelstein L. The mathematical modelling of metabolic and endocrine systems. John Wiley & Sons, New York 1983
  • Low J. M., Millard R. K., Curnow J. S. H., Hutton P., Prys-Roberts C. Servo-controlled infusion of sodium nitroprusside for induced hypotension. Quantitation, Modelling and Control of Anaesthesia, Stoeckel. Thieme-Stratton, Stuttgart-New York 1985
  • Westenskow D. R., Thomson D., Zlinden A. M. Volatile anaesthetic delivery using an uptake model and feedback control. Quantitation, Modelling and Control of Anaesthesia, Stoeckel. Thieme-Stratton, Stuttgart-New York 1985
  • Asbury A. J. Feedback control and model identification in the automatic control of neuromuscular blocade. Quantitation, Modelling and Control of Anaesthesia, Stoeckel. Thieme-Stratton, Stuttgart-New York 1985
  • Mason J., Price D. J. The control of intracranial pressure. IEE Colloquium on Control Techniques in Anaesthesia and Drug Administration. London 1981, Digest No 1981/45
  • Sheiner L. C. Computer-aided long term anticoagulation therapy. Computers and Biomedical Research 1969; 2
  • Sheppard L. C., Shotts J. F., Robertson N. F., Wallace F. D., Kouchoukos N. T. Computer controlled infusion of vasoactive drugs in post cardiac surgical patients. Proceedings of the First Annual Conference of IEEE Engineering in Medicine & Biology. Denver, Colorado 1979
  • Ingram D., Bloch R. Mathematical Methods in Medicine. Wiley, Chichester 1984, Pts 1 & 2
  • Pickup J. C. Clinical applications of infusion systems. Journal of Medical Engineering & Technology 1984; 8: 101–107

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.