Nuclear receptors in herb–drug interactions

References

• Bailey, D. G., Spence, J. D., Munoz, C., Arnold, J. M. (1991). Interaction of citrus juices with felodipine and nifedipine. Lancet 337:268–269.
   PubMed Web of Science ®Google Scholar
• Borrelli, F., Izzo, A. A. (2009). Herb-drug interactions with St John’s wort (Hypericum perforatum): an update on clinical observations. AAPS J 11:710–727.
   PubMed Web of Science ®Google Scholar
• Bourguet, W., Germain, P., Gronemeyer, H. (2000). Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications. Trends Pharmacol Sci 21:381–388.
   PubMed Web of Science ®Google Scholar
• Brobst, D. E., Ding, X., Creech, K. L., Goodwin, B., Kelley, B., Staudinger, J. L. (2004). Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J Pharmacol Exp Ther 310:528–535.
   PubMed Web of Science ®Google Scholar
• Burris, T. P., Montrose, C., Houck, K. A., Osborne, H. E., Bocchinfuso, W. P., Yaden, B. C. et al. (2005). The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand. Mol Pharmacol 67:948–954.
   PubMed Web of Science ®Google Scholar
• Chao, C. Y., Huang, C. J. (2003). Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl CoA oxidase gene in H4IIEC3 hepatoma cells. J Biomed Sci 10(6 Pt 2):782–791.
   PubMed Web of Science ®Google Scholar
• Chen, X. W., Sneed, K. B., Pan, S. Y., Cao, C., Kanwar, J. R., Chew, H. et al. (2012). Herb-drug interactions and mechanistic and clinical considerations. Curr Drug Metab 13:640–651.
   PubMed Web of Science ®Google Scholar
• Ding, X., Staudinger, J. L. (2005a). Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 312:849–856.
   PubMed Web of Science ®Google Scholar
• Ding, X., Staudinger, J. L. (2005b). The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter. J Pharmacol Exp Ther 314:120–127.
   PubMed Web of Science ®Google Scholar
• Eisenberg, D. M., Davis, R. B., Ettner, S. L., Appel, S., Wilkey, S., Van Rompay, M. et al. (1998). Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 280:1569–1575.
   PubMed Web of Science ®Google Scholar
• Fong, H. H. (2002). Integration of herbal medicine into modern medical practices: issues and prospects. Integr Cancer Ther 1:287–93; discussion 293.
   PubMedGoogle Scholar
• García-Rocha, M., García-Gravalos, M. D., Avila, J. (1996). Characterisation of antimitotic products from marine organisms that disorganise the microtubule network: ecteinascidin 743, isohomohalichondrin-B and LL-15. Br J Cancer 73:875–883.
   PubMed Web of Science ®Google Scholar
• Gunther, S., Patterson, R. E., Kristal, A. R., Stratton, K. L., White, E. (2004). Demographic and health-related correlates of herbal and specialty supplement use. J Am Diet Assoc 104:27–34.
   PubMed Web of Science ®Google Scholar
• Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P. W., Chan, E. et al. (2005). Herb-drug interactions: a literature review. Drugs 65:1239–1282.
   PubMed Web of Science ®Google Scholar
• Huang, W., Zhang, J., Moore, D. D. (2004). A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR. J Clin Invest 113:137–143.
   PubMed Web of Science ®Google Scholar
• Hwang, B. Y., Lee, J. H., Nam, J. B., Kim, H. S., Hong, Y. S., Lee, J. J. (2002). Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor gamma. J Nat Prod 65:616–617.
   PubMed Web of Science ®Google Scholar
• Izzo, A. A., Ernst, E. (2009). Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 69:1777–1798.
   PubMed Web of Science ®Google Scholar
• Jin, J., Bi, H., Hu, J., Zeng, H., Zhong, G., Zhao, L. et al. (2011). Effect of Wuzhi tablet (Schisandra sphenanthera extract) on the pharmacokinetics of paclitaxel in rats. Phytother Res 25:1250–1253.
   PubMed Web of Science ®Google Scholar
• Jin, J., Bi, H., Hu, J., Zhong, G., Zhao, L., Huang, Z. et al. (2010). Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats. Biopharm Drug Dispos 31:264–268.
   PubMed Web of Science ®Google Scholar
• Kennedy, D. A., Seely, D. (2010). Clinically based evidence of drug-herb interactions: a systematic review. Expert Opin Drug Saf 9:79–124.
   PubMed Web of Science ®Google Scholar
• Klepser, T. B., Doucette, W. R., Horton, M. R., Buys, L. M., Ernst, M. E., Ford, J. K. et al. (2000). Assessment of patients’ perceptions and beliefs regarding herbal therapies. Pharmacotherapy, 20:83–87.
   PubMed Web of Science ®Google Scholar
• Kliewer, S. A., Goodwin, B., Willson, T. M. (2002). The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 23:687–702.
   PubMed Web of Science ®Google Scholar
• Kliewer, S. A., Willson, T. M. (2002). Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor. J Lipid Res 43:359–364.
   PubMed Web of Science ®Google Scholar
• Lazarou, J., Pomeranz, B. H., Corey, P. N. (1998). Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279:1200–1205.
   PubMed Web of Science ®Google Scholar
• Ma, X., Shah, Y., Cheung, C., Guo, G. L., Feigenbaum, L., Krausz, K. W. et al. (2007). The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. Drug Metab Dispos 35:194–200.
   PubMed Web of Science ®Google Scholar
• Mae, T., Kishida, H., Nishiyama, T., Tsukagawa, M., Konishi, E., Kuroda, M. et al. (2003). A licorice ethanolic extract with peroxisome proliferator-activated receptor-gamma ligand-binding activity affects diabetes in KK-Ay mice, abdominal obesity in diet-induced obese C57BL mice and hypertension in spontaneously hypertensive rats. J Nutrition 133:3369–3377.
   PubMed Web of Science ®Google Scholar
• Mai, I., Krüger, H., Budde, K., Johne, A., Brockmöller, J., Neumayer, H. H. et al. (2000). Hazardous pharmacokinetic interaction of Saint John’s wort (Hypericum perforatum) with the immunosuppressant cyclosporin. Int J Clin Pharmacol Ther 38:500–502.
   PubMed Web of Science ®Google Scholar
• Mangelsdorf, D. J., Evans, R. M. (1995). The RXR heterodimers and orphan receptors. Cell 83:841–850.
   PubMed Web of Science ®Google Scholar
• Masahiko, N., Honkakoski, P. (2000). Induction of drug metabolism by nuclear receptor CAR: molecular mechanisms and implications for drug research. Eur J Pharm Sci 11:259–264.
   PubMed Web of Science ®Google Scholar
• Michalik, L., Auwerx, J., Berger, J. P., Chatterjee, V. K., Glass, C. K., Gonzalez, F. J. et al. (2006). International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacological Reviews 58:726–741.
   PubMed Web of Science ®Google Scholar
• Mills, E., Foster, B. C., van Heeswijk, R., Phillips, E., Wilson, K., Leonard, B. et al. (2005). Impact of African herbal medicines on antiretroviral metabolism. AIDS (London, England) 19:95–97.
   PubMed Web of Science ®Google Scholar
• Moore, L. B., Goodwin, B., Jones, S. A., Wisely, G. B., Serabjit-Singh, C. J., Willson, T. M. et al. (2000). St. John’s wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proc Natl Acad Sci USA 97:7500–7502.
   PubMed Web of Science ®Google Scholar
• Mu, Y., Zhang, J., Zhang, S., Zhou, H. H., Toma, D., Ren, S. et al. (2006). Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. J Pharmacol Exp Ther 316:1369–1377.
   PubMed Web of Science ®Google Scholar
• Perfetti, R., D’Amico, E. (2005). Rational drug design and PPAR agonists. Curr Diab Rep 5:340–345.
   PubMedGoogle Scholar
• Qin, X. L., Bi, H. C., Wang, X. D., Li, J. L., Wang, Y., Xue, X. P. et al. (2010). Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506). Int J Pharm 389:114–121.
   PubMedGoogle Scholar
• Raucy, J. L. (2003). Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. Drug Metab Dispos 31:533–539.
   PubMed Web of Science ®Google Scholar
• Richardson, W. H. 3rd, Slone, C. M., Michels, J. E. (2007). Herbal drugs of abuse: an emerging problem. Emerg Med Clin North Am 25:435–57; abstract ix.
   PubMed Web of Science ®Google Scholar
• Sato, M., Tai, T., Nunoura, Y., Yajima, Y., Kawashima, S., Tanaka, K. (2002). Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of noninsulin-dependent diabetes mellitus to insulin. Biol Pharm Bull 25:81–86.
   PubMed Web of Science ®Google Scholar
• Shi, S., Klotz, U. (2012). Drug interactions with herbal medicines. Clin Pharmacokinetics 51:77–104.
   PubMed Web of Science ®Google Scholar
• Sonoda, J., Pei, L., Evans, R. M. (2008). Nuclear receptors: decoding metabolic disease. FEBS Letters 582:2–9.
   PubMed Web of Science ®Google Scholar
• Sparreboom, A., Cox, M. C., Acharya, M. R., Figg, W. D. (2004). Herbal remedies in the United States: potential adverse interactions with anticancer agents. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 22:2489–2503.
   PubMed Web of Science ®Google Scholar
• Staudinger, J. L., Ding, X., Lichti, K. (2006). Pregnane X receptor and natural products: beyond drug-drug interactions. Expert Opinion on Drug Metabolism & Toxicology 2:847–857.
   PubMed Web of Science ®Google Scholar
• Synold, T. W., Dussault, I., Forman, B. M. (2001). The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nature Medicine 7:584–590.
   PubMed Web of Science ®Google Scholar
• Teotico, D. G., Bischof, J. J., Peng, L., Kliewer, S. A., Redinbo, M. R. (2008). Structural basis of human pregnane X receptor activation by the hops constituent colupulone. Molecular Pharmacology 74:1512–1520.
   PubMed Web of Science ®Google Scholar
• Wang, L., Li, F., Lu, J., Li, G., Li, D., Zhong, X. B. et al. (2010). The Chinese herbal medicine Sophora flavescens activates pregnane X receptor. Drug metabolism and disposition: the Biological Fate of Chemicals 38:2226–2231.
   PubMed Web of Science ®Google Scholar
• Wei, P., Zhang, J., Egan-Hafley, M., Liang, S., Moore, D. D. (2000). The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407:920–923.
   PubMed Web of Science ®Google Scholar
• Yu, C., Ye, S., Sun, H., Liu, Y., Gao, L., Shen, C. et al. (2009). PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA. Chemico-Biological Interactions 177:58–64.
   PubMed Web of Science ®Google Scholar
• Zhang, Y., Chan, J. F., Cummins, C. L. (2009). Liver X Receptors as Therapeutic Targets for Managing Cholesterol: Implications for Atherosclerosis and Other Inflammatory Conditions. Clinical Lipidology 4:29–40.
   PubMed Web of Science ®Google Scholar