References
- Kuhn T. S. The Structure of Scientific Theories, 2nd ed., F. Suppe. University of IIIinois Press, Urbana 1977; 459
- Kuhn T. S. The Structure of Scientific Revolutions, 2nd ed. University of Chicago Press, Chicago 1970; 43
- Boxenbaum H., Fertig J. B. Eur. J. Drug Metab. Pharmacokinet. 1984; 9: 177
- Churchman C. W. The Process of Model-Building in the Behavioral Sciences, R. M. Stogdill. Ohio State University Press, Columbus 1970; 133–138, chap. 8
- Cutler R. G. Testing the Theories of Aging, R. C. Adelman, G. S. Roth. CRC Press, Boca Raton, FL 1982; 25–114, chap. 2
- Calder I W. A., II. J. Theor. Biol. 1983; 102: 135
- Boxenbaum H. J. Pharmacokinet. Biopharm. 1982; 10: 201
- Wickramasinghe R. H., Villee C. A. Nature 1975; 256: 509
- Wickramsinghe R. H., Villee C. A. Perspect. Biol. Med. 1976; 19: 473
- Ishidate K., Kawaguchi K., Tagawa K., Hagihara B. J. Biochem. (Tokyo) 1969; 65: 375
- Tagawa K. Cytochrome P-450, R. Sato, T. Omura. Academic Press, New York 1978; 202–208, sec. 4.5
- Sato R. Cytochrome P-450, R. Sato, T. Omura. Academic Press, New York 1978; 23–35, chap. 2
- Alexander K. T. W., Mitropoulos K. A., Gibbons G. F. Biochem. Biophys. Res. Commun. 1974; 60: 460
- Hunter K., Rose A. H. The Yeasts, vol. 2: Physiology and Biochemistry of Yeasts, A. H. Rose, J. S. Harrison. Academic Press, New York 1971; 211–270, chap. 6
- Boxenbaum H. Drug Metab. Rev. 1983; 14: 1057
- Omura T. Cytochrome P-450, R. Sato, T. Omura. Academic Press, New York 1978; 1–21, chap. 1
- Wiseman A. Trends Biol. Sci. April, 1980; 102–104
- Katagiri M., Ganguli B. N., Gunsalus I. C. J. Biol. Chem. 1968; 243: 3543
- Cardini G., Jurtshuk P. J. Biol. Chem. 1968; 243: 6070
- Duppel W., Lebeault J.-M., Coon M. J. Eur. J. Biochem. 1973; 36: 583
- Madyastha K. M., Meehan T. D., Coscia C. J. Biochemistry 1976; 15: 1097
- Gibbons G. F., Mitropoulos K. A. Eur. J. Biochem. 1973; 40: 269
- Taniguchi S., Hoshita N., Okuda K. Eur. J. Biochem. 1973; 40: 607
- Sato R., Atsuta Y., Imai Y., Taniguchi S., Okuda K. Proc. Natl. Acad. Sci. U.S.A 1977; 74: 5477
- Boyd G. S., Grimwade A. M., Lawson M. E. Eur. J. Biochem. 1973; 37: 334
- Omura T., Sato R., Cooper D. Y., Rosenthal O., Estabrook R. W. Fed. Proc. 1965; 24: 1181
- Omura T., Sanders E., Estabrook R. W., Cooper D. Y., Rosenthal O. Arch. Biochem. Biophys. 1966; 117: 660
- Simpson E. R., Boyd G. S. Biochem. Biophys. Res. Commun. 1966; 24: 10
- Simpson E. R., Boyd G. S. Eur. J. Biochem. 1967; 2: 275
- Henry L. H., Norman A. W. J. Biol. Chem. 1974; 249: 7529
- Ghazarian J. G., Jefcoate C. R., Knutson J. C., Orme-Johnson W. H., DeLuca H. F. J. Biol. Chem. 1974; 249: 3026
- Bhattacharyya M. H., DeLuca H. F. Arch. Biochem. Biophys. 1974; 160: 58
- Wada F., Shibata H., Goto M., Sakamoto Y. Biochim. Biophys. Acta 1968; 162: 518
- ællin R., Orrenius S. Å. Pillotti, and C.-G. Swahn. Arch. Biochem. Biophys. 1973; 158: 597
- Murphy P. J., West C. A. Arch. Biochem. Biophys. 1969; 133: 395
- Keeton W. T. Biological Science. W. W. Norton, New York 1967; 299–320
- Potts J. R. M., Weklych R., Conn E. E. J. Biol. Chem. 1974; 249: 5019
- Murphy G., Vogel G., Krippahl G., Lynen F. Eur. J. Biochem. 1974; 49: 443
- Dobzhansky T. Studies in the Philosophy of Biology, F. J. Ayala, T. Dobzhansky. University of California Press, Berkeley 1974; 307–338, chap. 18
- Jondorf W. R. Drug Metab. Rev. 1981; 12: 379
- Sherwin C. P. Physiol. Rev. 1922; 2: 238
- Gaudette L. E., Brodie B. B. Biochem. Pharmacol. 1959; 2: 89
- Brodie B. B. Pharmacologist 1964; 6: 12
- Brodie B. B., Maickel R. P. Metabolic Factors Controlling Duration of Drug Action. Proc. 1st Int. Pharmacol. Meeting, B. B. Brodie, E. G. Erdös. Pergamon Press, New York 1962; vol. 6: 299–324
- Brodie B. B., Maickel R. P., Jondorf W. R. Fed. Proc. 1958; 17: 1163
- Brodie B. B. J. Pharm. Pharmacol. 1956; 8: 1
- Brodie B. B., Hogben C. A. M. J. Pharm. Pharmacol. 1957; 9: 345
- Ferguson M. The Aquarian Conspiracy: Personal and Social Transformation in the 1980s. J. P. Tareher, Los Angeles 1980; 162–167
- Simpson G. G. The Meaning of Evolution. New American Library of World Literature, A Mentor Book, New York 1951
- Sheppard P. M. Natural Selection and Heredity. Harper and Row, New York 1960
- Dollo L. Bull. Soc. Beige Géol. Pal. Hydr. 1893; 7: 164
- Whitrow G. J. The Natural Philosophy of Time, 2nd ed. Clarendon Press, Oxford 1980; 12–15; 54, 365
- Sinnott E. W. Cell and Psyche: The Biology of Purpose. Harper, New York 1950; 6
- Rowland M., Blaschke T. F., Meffin P. J., Williams R. L. The Effect of Disease States on Drug Pharmacokinetics, L. Z. Benet. Am. Pharm. Assoc. and Acad. Pharm. Sci., Washington, DC 1976; 53–75, chap 4
- Wilkinson G. R., Shand D. G. Clin. Pharmacol. Ther. 1975; 18: 377
- Hofstadter D. R. Gödel, Escher, Bach: An Etnernal Golden Braid. Vintage Books, New York 1980; 544–545
- Brattsten L. B., Wilkinson C. F., Eisner T. Science 1977; 196: 1349
- Steinbuch K., Lipp H. M. Technical and Biological Problems of Control: A Cybernetic View, A. S. Iberall, J. B. Reswick. Instrument Society of America, Pittsburgh 1970; 810–816, Int. Fed. Automatic Control, distributed by
- Seydel J. K., Schaper K.-J. Pharmacol. Ther. 1982; 15: 131
- Hansch C., Steward A. R., Anderson S. M., Bentley D. J. Med. Chem. 1967; 11: 1
- Toon S., Rowland M. J. Pharmacol. Exp. Ther. 1983; 225: 752
- Mayr E. Populations, Species, and Evolution. Belknap Press of Harvard University Press, Cambridge, MA 1970
- Sacher G. A. BioScience 1978; 28: 497
- Sacher G. A. Genetics of Ageing, E. L. Schneider. Plenum Press, New York 1978; 151–168, chap. 6
- Williams G. C. Evolution 1957; 11: 398
- Sacher G. A. Perspectives in Experimental Gerontology, N. W. Shock. C. C. Thomas, Springfield, IL 1966; 326–335
- Williams G. M., Weisburger J. H. A Guide to General Toxicology, F. Homburger, J. A. Hayes, E. W. Pelikan. Karger, Basel 1983; 212–226, chap. 12
- Kirkwood T. B. L., Cremer T. Hum. Genet. 1982; 60: 101
- Breimer D. D. Clin. Pharmacokinet. 1983; 8: 371
- Vesell E. S., Penno M. B. Clin. Pharmacokinet. 1983; 8: 378
- Novikoff A. B. Science 1945; 101: 209
- Whyte L. L. The Unitary Principle in Physics and Biology. Cresset Press, London 1949; 82
- Thorpe W. H. Studies in the Philosophy of Biology: Reduction and Related Problems, F. J. Ayala, T. Dobzhansky. University of California Press, Berkeley 1974; 109–138, chap. 8
- Grobstein C. Hierarchy Theory: The Challenge of Complex Systems, H. H. Pattee. George Braziller, New York 1973; 29–47, chap. 2
- Lester D., Keokosky W. Z. Life Sci, part I, 6 1967; 2313
- Videla L., Flattery K. V., Sellers E. A., Israel Y. J. Pharmacol. Exp. Ther. 1975; 192: 575
- Wagner G. J., Wilkinson P. K., Sedman A. J., Kay D. R., Weidler D. J. J. Pharm. Sci. 1976; 65: 152
- Mellett L. B. Prog. Drug Res. 1969; 13: 136
- Günther B. Physiol. Rev. 1975; 55: 659
- Butler T. C. (1966) Proceedings of the Conference on Non-human Primate Toxicology, Arlington, VA, June 12–14, 1966, C. O. Miller. U.S. Government Printing Office, Washington, DC, 57–74
- Weiss M., Sziegoleit W., Förster W. Int. J. Clin. Pharmacol. 1977; 15: 572
- Calder I W. A., II. Am. J. Physiol. 1983; 244: R601
- Edwards N. A. Comp. Biochem. Physiol. A 1975; 52: 63
- Adolph E. F. Science 1949; 109: 579
- Dedrick R. L., Forrester D. D., Cannon J. N., El Dareer S. M., Mellett L. B. Biochem. Pharmacol. 1973; 22: 2405
- King F. G., Dedrick R. L., Collins J. M., Matthews H. B., Birnbaum L. S. Toxicol. Appl. Pharmacol. 1983; 67: 390
- Boxenbaum H. J. Pharmacokinet. Biopharm. 1980; 8: 165
- Swabb E. A., Bonner D. P. J. Pharmacokinet. Biopharm. 1983; 11: 215
- King F. G., Dedrick R. L. Cancer Treatment Rep. 1979; 63: 1939
- Dedrick R. L., Bischoff K. B., Zaharko D. S. Cancer Chemother. Rep., part I, 54 1970; 95
- Andersen M. E. Drug Metab. Rev. 1982; 13: 799
- Gillette J. R. Ann. NY Acad. Sci. 1971; 179: 43
- Gibaldi M., Perrier D. Pharmacokinetics, 2nd ed. Dekker, New York 1982; 199–219, chap. 5
- Rowland M., Tozer T. N. Clinical Pharmacokinetics: Concepts and Applications. Lea and Febiger, Philadelphia 1980; 43–47
- Walker C. H. Prog. Drug Metab. 1980; 5: 113
- Walker C. H. Drug Metab. Rev. 1978; 7: 295
- Apostel L. The Concept and the Role of the Model in Mathematics and Natural and Social Sciences, H. Freuden-thal. Gordon and Breach, New York 1961; 11
- Sjenitzer F. cited. Scaling-Up of Chemical Plant Processes, J. M. Piriehonorary. Institution of Chemical Engineers, London 1957; S26–S27
- Boxenbaum H., Fertig J. B. Biopharm. Drug Dispos 1984; 5, in press
- Holt J. P., Rhode E. A. Am. Heart J. 1976; 92: 465
- Zaharko D. S., Dedrick R. L., Oliverio V. T. Comp. Biochem. Physiol., 42A 1972; 183
- Fischer R. The Voices of Time, J. T. Fraser. George Braziller, New York 1966; 357–382
- Fischer R. Ann. NY Acad. Sci. 1967; 138: 440
- Van Straalen N. M. J. Theor. Biol. 1983; 104: 349
- Boxenbaum H., Ronfeld R. Am. J. Physiol. 1983; 245: R768
- Sacher G. A. Ciba Found. Colloq. Aging 1959; 5: 115
- Texas Instruments Inc. Applied Statistics, manual for the Texas Instrument programmable 58/59 calculators 1977; 5–16; 5–17
- Metzler C. M., Elfring G. L., McEwen A. J. A User's Manual for NONLIN and Associated Programs. Upjohn Co., Kalamazoo, MI April 20, 1974
- SAS User's Guide; Statistics, A. A. Ray. SAS Institute, Cary, NC 1982
- Doyle E., Chasseaud L. F. Toxicology 1981; 19: 159
- Data on file. Hoffmann-La Roche Inc., Nutley, NJ
- Bekersky I., Maggio A. C., Mattaliano V., Jr., Boxenbaum H. G., Maynard D. E., Cohn P. D., Kaplan S. A. J. Pharmacokinet. Biopharm. 1977; 5: 507
- Hansard S. L. Am. J. Physiol. 1964; 206: 1369
- Shetty S. N., Himes J. A., Edds G. T. Am. J. Vet. Res. 1972; 33: 935
- Johannessen W., Gadeholt G., Aarbakke J. J. Pharm. Pharmcol. 1981; 33: 365
- Swartz R. D., Sidell F. R., Cucinell S. A. J. Pharmacol. Exp. Ther. 1974; 188: 1
- Whiting F., Balch C. C., Campling R. C. Br. J. Nutr. 1960; 14: 519
- Sams R. personal communication. Ohio State Univ. School of Veterinary Medicine
- Van Peer A., Belpaire F., Bogaert M. Pharmacology 1978; 17: 307
- Hoffman B. Albert Einstein, Creator and Rebel. Plume, New York 1973; 257
- Dossey L. Space. Time and Medicine, Shambhala, Boulder, CO 1982
- Sacher G. A. Handbook of the Biology of Aging, C. E. Finch, L. Hayflick. Van Nostrand Reinhold, New York 1977; 582–638, chap. 24
- Ouspensky P. D. Tertium Organum. Vintage Books, New York 1982, original copyright 1920 by Manus Press
- Rucker B. R. V. Geometry, Relativity and the Fourth Dimension. Dover Publications, New York 1977
- Speculations on the Fourth Dimension: Selected Writings of Charles H. Hinton, B. R. V. Rucker. Dover Publications, New York 1980
- Ouspensky P. D. In Search of the Miraculous. Harcourt, Brace and World, New York 1949; 199–216
- Ouspensky P. D. A New Model of the Universe. Vintage Books, New York 1971; 61–100, chap. II, originally published by Alfred A. Knopf in 1931
- Gamow G. One Two Three… Infinity. New American Library. 1947; 70–88, chap. IV
- Carrel A. Man, The Unknown. MacFadden Publications, New York 1961; 108–127, chap. V, copyright 1935, 1939 by Harper and Brothers
- Capra F. The Tao of Physics. Bantam Books, Toronto 1975
- LeShan L., Margenau H. Einstein's Space and Van Gogh's Sky. Macmillan, New York 1982
- The Fourth Dimension Simply Explained, H. P. Manning. Dover Publications, New York 1960, originally published in 1910 by Munn and Company
- Briggs J. P., Peat F. D. Looking Glass Universe: The Emerging Science of Wholeness. Simon and Schuster, New York 1984
- Jones R. S. Physics as Metaphor. New American Library, New York 1982
- Boxenbaum H., Murray W., Markin R., Ciraulo D. Pharmacokinetics and Pharmacodynamics of Psychoactive Drugs. Dekker, New York, in press
- Pearl R. The Rate of Living. A. A. Knopf, New York 1928
- Rubner M. Mitt. Ges. inn. Med., Wien 1908; 7: 58
- Boddington M. J. J. Theor. Biol. 1978; 75: 443
- Gould S. J. Biol. Rev. 1966; 41: 587
- Brody S. Bioenergetics and Growth. Hafner, New York 1964; 352–403
- Kleiber M. J. Theor. Biol. 1975; 53: 199
- Boxenbaum H., Ronfeld R. Pharmacokinetics: A Modern View. Proceedings of the Sidney Riegelman Memorial Symposium. San Francisco, CA April 22–24, 1982, in press
- The Illustrated London News July 5, 1958; 233(No. 6213)17
- Biology Data Book, 2nd ed., P. L. Altman, D. S. Dittmer. Fed. Am. Soc. Exp. Biol., Bethesda, MD 1972; vol. I: 229–235
- Seely S. Med. Hypotheses 1980; 6: 873
- Drabkin D. L. Perspect. Biol. Med. 1959; 2: 473
- Evans D. A. P., Storey P. B., McKusick V. A. Bull. Johns Hopkins Hosp. 1961; 108: 60
- Richardson I. W., Rosen R. J. Theor. Biol. 1979; 79: 415
- Ornstein R. E. On the Experience of Time. Penguin Books, Harmondsworth 1969; 23
- Bischoff K. B., Dedrick R. L. J. Pharm. Sei. 1968; 57: 1346
- Lindsay R. B., Margenau H. Foundations of Physics. Wiley, New York 1936; 59–78, chap. II