25
Views
15
CrossRef citations to date
0
Altmetric
Research Article

New Micro-Optical Methods to Study Metabolism in Periportal and Pericentral Regions of the Liver Lobule'

&
Pages 263-281 | Published online: 22 Sep 2008

References

  • Loud A. V. A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells. J. Cell Biol 1968; 37: 27–46
  • Jungermann K., Sasse D. Heterogeneity of liver parenchymal cells. Trends Biochem. Sci. 1978; 3: 198–202
  • Pathology of the Liver, R. N.M. MacSween, P. P. Anthony, P. J. Scheuer. Churchill Livingstone, Edinburgh 1979
  • Zimmerman H. J. Hepatotoxicity. Appleton-Century-Crofts, New York 1978
  • Ji S., Chance B., Nishiki K., Smith T., Rich T. Micro-light guides, a new method for measuring tissue fluorescence and reflectance. Am. J. Physiol 1979; 236: C144–C156
  • Ji S., Lemasters J. J., Thurman R. G. A non-invasive method to study metabolic events within sublobular regions of hemoglobin-free perfused liver. FEBS Lett 1980; 113: 37–41, Ibid. 114:349.
  • Zahlten R. N., Stratman F. W., Lardy H. A. Regulation of glucose synthesis in hormone-sensitive isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 1973; 70: 3213–3218
  • Ji S., Lemasters J. J., Christenson V., Thurman R. G. Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver: Evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia. Proc. Natl. Acad. Sci. USA 1982; 79: 5415–5419
  • Lemasters J. J., Ji S., Thurman R. G. Approaches to studying sublobular structure and function in the isolated, perfused rat liver. Regulation of Hepatic Metabolism: Intra- and Intercellular Compartmentation, R. G. Thurman, F. C. Kauffman, K. Jungermann. Plenum Press, New York 1986
  • Baron J., Redick J. A., Guengerich F. P. Im-munohistochemical localizations of cytochromes P-450 in rat liver. Life Sci 1978; 23: 2627–2632
  • Gooding P. E., Chayen J., Sawyer B., Slater T. F. Cytochrome P-450 distribution in rat liver and the effect of sodium phenobarbitone administration. Chem.-Biol. Interact 1978; 20: 299–310
  • Sies H. Nicotinamide nucleotide compartmentation. Metabolic Compartmentation, H. Sies. Academic Press, London 1982; 205–231
  • Chance B., Cohen P., Jobsis F., Schoener B. Intracellular oxidation-reduction states in vivo. Science 1962; 137: 499–508
  • Lemasters J. J., Ji S., Thurman R. G. Centrilobular injury following hypoxia in isolated, perfused rat liver. Science 1981; 213: 661–663
  • Belinsky S. A., Kauffman F. C., Ji S., Lemasters J. J., Thurman R. G. Stimulation of mixed-function oxidation of 7-ethoxycoumarin in periportal and pericentral regions of the perfused rat liver by xylitol. Eur. J. Biochem 1983; 137: 1–6
  • Ghosh A. K., Finegold D., White W., Zawalich K., Matschinsky F. W. Quantitative histochemical resolution of the oxidation-reduction and phosphate potentials within the simple hepatic acinus. J. Biol. Chem 1982; 257: 5476–5481
  • Ji S., Beckh K., Jungermann K. Regulation of oxygen consumption and microcirculation by a-sympathetic nerves in isolated perfused rat liver. FEBS Lett 1984; 167: 117–122
  • Thurman R. G., Kauffman F. C. Sublobular compart-mentation of pharmacological events (SCOPE): Metabolic fluxes in periportal and pericentral regions of the liver lobule. Hepatology 1985; 5: 144–151
  • Thurman R. G., Kauffman F. C., Baron J. Biotransformation and zonal toxicity. Regulation of Hepatic Metabolism: Intra-and Intercellular Compartmentation, R. Thurman, F. C. Kauffman, K. Jungermann. Plenum Press, New York 1986
  • Kashiwagi T., Ji S., Lemasters J. J., Thurman R. G. Rates of alcohol dehydrogenase-dependent ethanol metabolism in periportal and pericentral regions of the perfused rat liver. Mol. Pharmacol 1982; 21: 438–443
  • Kashiwagi T., Lindros K. O., Thurman R. G. Aldehyde dehydrogenase-dependent acetaldehyde metabolism in periportal and pericentral regions of the perfused rat liver. J. Pharmacol. Exp. Ther 1983; 224: 538–542
  • Belinsky S. A., Matsumara T., Kauffman F. C., Thurman R. G. Rates of allyl alcohol metabolism in periportal and pericentral regions of the liver lobule. Mol. Pharmacol 1984; 25: 158–164
  • Matsumura T., Thurman R. G. Predominance of glycolysis in pericentral regions of the liver lobule. Eur. J. Biochem 1984; 140: 229–234
  • Ji S., Lemasters J. J., Thurman R. G. A fluorometric method to measure sublobular rates of mixed-function oxidation in the hemoglobin-free perfused rat liver. Mol. Pharmacol 1981; 19: 513–516
  • Conwa J. G., Kauffman F. C., Ji S., Thurman R. G. Rates of sulfation and glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule. Mol. Pharmacol 1982; 22: 509–516
  • Conway J. G., Kauffman F. C., Tsukada T., Thurman R. G. Glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule. Mol. Pharmacol 1984; 25: 487–493
  • Conway J. G., Popp J. A., Ji S., Thurman R. G. Effect of size on portal circulation of hepatic nodules from carcinogen-treated rats. Cancer Res, 43: 3374–3378
  • Thurman R. G., Ji S., Lemasters J. J. Lobular oxygen gradients: Possible role in alcohol-induced hepatotoxicity. Regulation of Hepatic Metabolism: Intra- and Intercellular Com-partmentation, R. G. Thurman, F. C. Kauffman, K. Junger-Mann. Plenum Press, New York 1986

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.