98
Views
17
CrossRef citations to date
0
Altmetric
Original Article

Adrenergic Modulation of Hepatotoxicity

, &
Pages 329-353 | Published online: 15 Feb 2010

References

  • Calvert D. N., Brody T. M. ldquo;Role of the sympathetic nervous system in CC 14 hepatotoxicity”. Am. J. Physiol. 1960; 198: 669–676
  • Brody T. M., Calvert D. N., Schneider A. F. Alteration of carbon tetrachloride-induced pathological changes in the rat by spinal transection, adrenalectomy and adrenergic blocking agents. J. Pharmacol. Exp. Ther. 1961; 131: 341–345
  • Larson R. E., Plaa G. L. Spinal cord transection and CCl4 toxicity. Experientia 1963; 19: 604–606
  • Larson R. E., Plaa G. L. A correlation of the effects of cervical cordotomy, hypothermia, and catecholamines and carbon tetrachloride-induced hepatic necrosis. J. Pharmacol. Exp. Ther. 1965; 147: 103–111
  • Larson R. E., Plaa G. L., Brody M. J. ldquo;Immunological sympathectomy and CC14 hepatotoxicity”. Proc. Soc. Exp. Biol. Med. 1964; 116: 557–560
  • Larson R. E., Plaa G. L., Crews L. M. ldquo;The effect of spinal cord transection on carbon tetrachloride hepatotoxicity”. Toxicol. Appl. Pharmacol. 1964; 6: 154–162
  • Kurstak C., Cote M. G., Plass G. L. ldquo;Effect of hypothermia on carbon tetrachloride-induced changed in hepatic ultrastructure”. Toxicol. Appl. Pharmacol. 1973; 26: 14–28
  • Schwetz B. A., Plaa G. L. ldquo;Catecholamine potentiation of carbon tetrachloride-induced hepatotoxicity in mice”. Toxicol. Appl. Pharmacol. 1969; 14: 495–509
  • Iwai M., Saheki S., Ohta Y., Shimazu T. ldquo;Footshock stress accelerates carbon tetrachloride-induced liver injury in rats: Implication of the sympathetic nervous system”. Biomed. Res. 1986; 7: 145–154
  • Kulcsar-Gergely J., Kulcsar A. ldquo;The influence of a ganglion-blocking agent on experimental liver injury”. Toxicology 1973; 1: 125–130
  • Wei E., Wong L. C. K., Hine C. H. ldquo;Potentiation of carbon tetrachloride hepatotoxicity by ethanol and cold”. Toxicol. Appl. Pharmacol. 1971; 18: 329–334
  • Roberts S. M., Harbison R. D., Seng J. E., James R. C. ldquo;Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine”. Toxicol. Appl. Pharmacol. 1991; 111: 175–188
  • Roberts S. M., Harbison R. D., James R. C. ldquo;Methamphetamine potentiation of carbon tetrachloride hepatotoxicity in mice”. J. Pharmacol. Exp. Ther. 1994; 271: 1051–1057
  • Roberts S. M., Harbison R. D., Westhouse R. A., James R. C. ldquo;Exacerbation of carbon tetrachloride-induced liver injury in the rat by methamphetamine”. Toxicol. Lett. 1995; 76: 77–83
  • Roberts S. M., Harbison R. D., James R. C. ldquo;Mechanistic studies on the potentiation of carbon tetrachloride hepatotoxicity by methamphetamine”. Toxicology 1995; 97: 49–57
  • Iwai M., Shimazu T. ldquo;Effects of ventromedial and lateral hypothalamic stimulation on chemically-induced liver injury in rats”. Life Sci. 1988; 42: 1833–1840
  • Zempel J. A., Dietz F. K., Traiger G. J. Effect of amphetamine, methamphetamine, and vasopressin on the hepatotoxicity of CCl4, CHBr3, and CHCL3. Pharmacologist 1983; 25: 169
  • Strubelt O., Breining H. Influence of hypoxia on the hepatotoxic effects of carbon tetrachloride, paracetamol, allyl alcohol, bromobenzene, and thioacetamide. Toxicol. Lett. 1980; 6: 109–113
  • Shen E. S., Garry V. F., Anders M. W. ldquo;Effect of hypoxia on carbon tetrachloride hepatotoxicity”. Biochem. Pharmacol. 1982; 31: 3787–3793
  • Siegers C. P., Horn W., Younes M. ldquo;Effect of hypoxia on the metabolism and hepatotoxicity of carbon tetrachloride and vinylidene chloride in rats”. Acta Pharmacol. Toxicol. 1985; 56: 81–86
  • Mitchell J. R., Jollow D. J., Potter W. Z., Gillette J. R., Brodie B. B. ldquo;Acetaminopohen-induced hepatic necrosis. IV. Protective role of glutathione”. J. Pharmacol. Exp. Ther. 1973; 187: 211–217
  • Jollow D. J., Mitchell J. R., Potter W. Z., Davis D. C., Gillette J. R., Brodie B. B. ldquo;Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo”. J. Pharmacol. Exp. Ther. 1973; 187: 195–202
  • Hinson J. A. ldquo;Biochemical toxicology of acetaminophen”. Rev. Biochem. Toxciol. 1980; 69: 279–290
  • James R. C., Roberts S. M., Harbison R. D. The perturbation of hepatic glutathione by α2 adrenergic agonists. Fundam. Appl. Toxicol. 1983; 3: 303–308
  • James R. C., Schieffer M. A., Roberts S. M., Harbison R. D. ldquo;Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine”. J. Pharmcol. Exp. Ther. 1987; 242: 726–732
  • Estrela J. M., Gil F., Vila J. M., Vina J. α-Adrenergic modulation of glutathione metabolism in isolated rat hepatocytes. Am. J. Physiol. 1988; 255: E801–E805.
  • Harbison R. D., James R. C., Roberts S. M. ldquo;Hepatic glutahione suppression by the α-adrenoreceptor stimulating agents phenylephrine and clonidine”. Toxicology 1991; 69: 279–290
  • James R. C., Harbison R. D., Roberts S. M. ldquo;Phenylpropanolamine potentiation of acetaminophen-induced hepatotoxicity: Evidence for a glutathione-dependent mechanism”. Toxicol. Appl. Pharmacol. 1993; 118: 159–168
  • Mehta H., Murray B., Loiudice T. A. ldquo;Hepatic dysfunction due to intravenous abuse of methylphenidate hydrochloride”. J. Clin. Gastroenterol. 1984; 6: 149–151
  • Goodman C. R. Hepatotoxicity due to methylphenidate hydrochloride. NY State J. Med. 1972; 72: 2339–2340
  • Roberts S. M., Harbison R. D., Roth L., James R. C. ldquo;Methylphenidate-induced hepatotoxicity in mice and its potentiation by β-adrenergic agonist drugs”. Life Sci. 1994; 55: 269–281
  • Boelsterli U. A., Goeldin C. ldquo;Biomechanisms of cocaine-induced hepatocyte injury mediated by the formation of reactive metabolites”. Toxicology 1991; 65: 351–360
  • Evans M. A., Harbison R. D. ldquo;Cocaine-induced hepatotoxicity in mice”. Toxicol. Appl. Pharmacol. 1978; 45: 739–754
  • Evans M. A. ldquo;Role of protein binding in cocaine-induced hepatic necrosis”. J. Pharmacol. Exp. Ther. 1983; 224: 73–79
  • Thompson M. L., Schuster L., Shaw K. ldquo;Cocaine-induced necrosis in mice”. Biochem. Pharmacol. 1979; 28: 2389–2395
  • Van Dyke C., Byck R. Cocaine and other stimulants, in Advances in Behavioral Biology, E. H. Ellinwood, M. M. Kelby. Plenum Press, New York 1978
  • Chieuh C. C., Kopin I. J. ldquo;Centrally mediated release by cocaine of endogenous epinephrine from the sympathoadrenal medullary system of unanesthetized rats”. J. Pharmcal. Exp. Ther. 1978; 205: 148–154
  • Reid W. D., Christie B., Krishna G., Mitchell J. R., Moskowitz J., Brodie B. B. ldquo;Bromobenzene metabolism and hepatic necrosis”. Pharmacology 1971; 6: 41–55
  • Lau S. S., Monks T. J. ldquo;The contribution of bromobenzene to our current understanding of chemically-induced toxicities”. Life Sci. 1988; 42: 1259–1269
  • Monks T. J., Hinson J. A., Gillette J. R. Bromobenzene and p-bromophenol toxicity and covalent binding in vivo. Life Sci. 1982; 30: 841–848
  • Fisher R., Brendel K., Hanzlik R. P. Correlation of metabolism, covalent binding and toxicity for a series of bromobenzene derivatives using rat liver slices in vitro. Chem.–Biol. Interact. 1993; 88: 191–208
  • Jollow D. J., Mitchell J. R., Zampaglione N., Gillete J. R. Bromobenzene-induced liver necrosis: Protective role of glutahione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 1974; 11: 151–169
  • Thor H., Svensson S., Hartzell P., Orrenius S. Biotransformation of bromobenzene to reactive metabolites by isolated hepatocytes. Biological Reactive Intermediates, R. Snyder, D. V. Parke, J. J. Kocsis, D. J. Jollow, G. G. Gibson, D. M. Witmer. Plenum, New York 1982; 287–298, II, Part A
  • Smith C. V., Hughes H., Mitchell J. R. Free radicals in vivo covalent binding to lipids. Mol. Pharmacol. 1984; 26: 112–116
  • Slaughter D. E., Zheng J., Harriman S., Hanzlik R. P. ldquo;Identification of covalent adducts to protein sulfur nucleophiles by alkaline permethylation”. Anal. Biochem. 1993; 208: 288–295
  • Hanzlik R. P., Harriman S. P., Frauenhoff M. M. ldquo;Covalent binding of benzoquinone to reduced ribonuclease: Adduct structures and stoichiometry”. Chem. Res. Toxicol. 1994; 7: 177–184
  • Orrenius S., Mc Conkey D. J., Bellomo G., Nicotera P. Role of Ca2+ in toxic cell killing. Trends Pharmacol. Sci. 1989; 10: 281–285
  • Lamb R. G., Mc Cue S. B., Taylor D. R., Mc Guffin M. A. ldquo;The role of phospholipid metabolism in bromobenzene- and carbon tetrachloride-dependent hepatocyte injury”. Toxicol. Appl. Pharmacol. 1984; 75: 510–520
  • Kerger B. D., Gandy J., Bucci T. J., Roberts S. M., Harbison R. D., James R. C. Antagonism of bromobenzene-induced hepatotoxicity by the α-adrenergic blocking agents, phentolamine and idazoxan. Toxicol. Appl. Pharmacol. 1988; 95: 12–23
  • Kerger B. D., Roberts S. M., Hinson J. A., Gandy J., Harbison R. D., James R. C. Antagonism of bromobenzene-induced hepatotoxicity by phentolamine: Evidence for a metabolism-independent intervention. Toxicol. Appl. Pharmacol. 1988; 95: 24–31
  • Kerger B. D., Roberts S. M., Harbison R. D., James R. C. ldquo;Antagonism of bromobenzene-induced hepatotoxicity by the α-adrenoreceptor blocking agents phentolamine and idazoxan: Role of hypothermia”. Toxicol. Appl. Pharmacol. 1989; 97: 360–369
  • Harbison R. D., Gill J., Roberts S. M., De Mott R. P. Reevaluation of adrenoreceptor mediated hepatoprotection from bromobenzene. The Toxicologist 1996; 16: 1486, abstract
  • Keck F. S., Wolf C., Foldenauer A., Zeller G., Kerner W., Pfeiffer E. F. ldquo;Hepatic sulfhydryl content under adrenergic stimulation in male rats”. Drug Res. 1991; 41: 6–9
  • Alvarez C., Blade C., Cartana J. α2-Adrenergic blockade prevents hyperglycemia and hepatic glutathione depletion in nickel-injected rats. Toxicol. Appl. Pharmacol. 1993; 121: 112–117
  • De Mott R. P., James R. C., Roberts S. M., Harbison R. D. Antagonism of bromobenzene-induced hepatotoxicity following delayed administration of phentolamine. The Toxicologist 1994; 14(1)699, abstract
  • Mac Donald J. R., Gandolfi A. J., Sipes I. G. ldquo;Cysteamine modulation of galactosamine-induced hepatotoxicity”. Toxicol. Appl. Pharmacol. 1984; 73: 551–558

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.