Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 24, 2000 - Issue 3
43
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The Mutation Associated with Hb Peterborough [β111(G13)Val→Phe] Originated from Southern Italy

, , , , , , & show all
Pages 227-237 | Received 08 Nov 1999, Accepted 27 Jan 2000, Published online: 07 Jul 2009

References

  • King M. A.R., Wiltshire B. G., Lehmann H., Morimoto H. An unstable haemoglobin with reduced oxygen affinity: Haemoglobin Peterborough, β111 (G13) Valine→Phenylalanine, its interaction with normal haemoglobin and with Haemoglobin Lepore. Br. J. Haematol. 1972; 22: 125–134
  • Nakanishi T., Miyazaki A., Kishikawa M., Shimizu A., Aoki Y., Kikuchi M. Hb Peterborough [β111(G13)Val→Phe] in Japan; rapid identification by ESI/MS using proteolytic digests of oxidized globin. Hemoglobin 1998; 22: 23–35
  • Carrell R. W., Kay R. A simple method for the detection of unstable haemoglobins. Br. J. Haematol. 1972; 23: 615–619
  • Marsh G., Marino G., Pucci P., Ferranti P., Malorni A., Kaeda J., Marsh J., Luzzato L. A third instance of the high oxygen affinity variant, Hb Heathrow [β103(G5) Phe→Leu]: identification of the mutation by mass spectrometry and by DNA analysis. Hemoglobin 1991; 15: 43–51
  • Carbone V., Salzano A. M., Pagano L., Viola A., Buffardi S., De Rosa C., Pucci P. Hb Rainier [β145(HC2)Tyr→Cys] in Italy. Characterization of the amino acid substitution and the DNA mutation. Hemoglobin 1999; 23: 111–124
  • Old J. M., Varawalla N. Y., Weatherall D. J. Rapid detection and prenatal diagnosis of α-thalassaemia: studies in Indian and Cypriot populations in the UK. The Lancet 1990; 6: 834–837
  • Orkin S. H., Kazazian H. H., Jr., Antonarakis S. E., Goff S. C., Boehm C. D., Sexton J. P., Waber P. G., Giardina P. J.V. Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster. Nature 1982; 296: 627–631
  • Como P. F., Wylie B. R., Trent R. J., Bruce D., Volpato F., Wilkinson T., Kronenberg H., Holland R. A.B., Tibben E. A. A new unstable and low oxygen affinity hemoglobin variant: Hb Stanmore [β111(G13) Val→Ala]. Hemoglobin 1991; 15: 53–65

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.