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Hemoglobin
international journal for hemoglobin research
Volume 34, 2010 - Issue 3
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Research Article

Iron Chelation for Amelioration of Liver Ischemia-Reperfusion Injury

Nikolaos Arkadopoulos Experimental Surgical Laboratory, Athens University School of Medicine, Aretaieion University Hospital, Athens, GreeceCorrespondence[email protected]
,
Constantinos Nastos Experimental Surgical Laboratory, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
,
Konstantinos Kalimeris Second Department of Anesthesiology, Athens University School of Medicine, Attikon University Hospital, Athens, Greece
,
Emmanuil Economou Biopathology Laboratory, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
,
Kassiani Theodoraki First Department of Anesthesiology, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
,
Evangelia Kouskouni Biopathology Laboratory, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
,
Agathi Pafiti Department of Pathology, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
,
Georgia Kostopanagiotou Second Department of Anesthesiology, Athens University School of Medicine, Attikon University Hospital, Athens, Greece
&
Vassilios Smyrniotis Experimental Surgical Laboratory, Athens University School of Medicine, Aretaieion University Hospital, Athens, Greece
 show all
Pages 265-277 | Published online: 04 Jun 2010

REFERENCES

  • Serracino-Inglott F, Habib NA, Mathie RT. Hepatic ischemia-reperfusion injury. Am J Surg. 2001;181(2):160–166.
  • Smyrniotis V, Farantos C, Kostopanagiotou G, Arkadopoulos N. Vascular control during hepatectomy: review of methods and results. World J Surg. 2005;29(11):1384–1396.
  • Gujral JS, Bucci TJ, Farhood A, Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology. 2001;33(2):397–405.
  • Schindl M, Redhead D, Fearon K, Garden O, Wigmore S. The value of residual liver volume as a predictor of hepatic dysfunction and infection after major liver resection. Gut 2005;54(2):289–296.
  • Arora AS, Gores GJ. The role of metals in ischemia/reperfusion injury of the liver. Semin Liver Dis. 1996;16(1):31–38.
  • DeBoer DA, Clark RE. Iron chelation in myocardial preservation after ischemia-reperfusion injury: the importance of pretreatment and toxicity. Ann Thorac Surg. 1992;53(3):412–418.
  • Arkadopoulos N, Vlahakos D, Kostopanagiotou G, Iron chelation attenuates intracranial pressure and improves survival in a swine model of acute liver failure. Liver Transpl. 2008;14(8):1116–1124.
  • Colletti LM, Remick DG, Campbell DA Jr. Desferal attenuates TNF release following hepatic ischemia/reperfusion. J Surg Res. 1994;57(4):447–453.
  • Drugas GT, Paidas CN, Yahanda AM, Ferguson D, Clemens MG. Conjugated desferoxamine attenuates hepatic microvascular injury following ischemia/reperfusion. Circ Shock. 1991;34(2):278–283.
  • Galaris D, Barbouti A, Korantzopoulos P. Oxidative stress in hepatic ischemia-reperfusion injury: the role of antioxidants and iron chelating compounds. Curr Pharm Des. 2006;12(23):2875–2890.
  • Omar R, Nomikos I, Piccorelli G, Savino J, Agarwal N. Prevention of postischaemic lipid peroxidation and liver cell injury by iron chelation. Gut. 1989;30(4):510–514.
  • Polat C, Tokyol C, Kahraman A, Sabuncuoglu B, Yilmaz S. The effects of deferoxamine and quercetin on hepatic ischemia-reperfusion induced renal disturbance. Prostaglandins Leukot Essent Fatty Acids 2006;74(6):379–383.
  • Tokyol C, Yilmaz S, Kahraman A, Cakar H, Polat C. The effects of deferoxamine and quercetin on liver injury induced by hepatic ischaemia-reperfusion in rats. Acta Chir Belg. 2006;106(1):68–72.
  • Galaris D, Pantopoulos K. Oxidative stress and iron homeostasis: mechanistic and health aspects. Crit Rev Clin Lab Sci. 2008;45(1):1–23.
  • Sanan S, Sharma G, Malhotra R, Sanan DP, Jain P, Vadhera P. Protection by deferoxamine against histopathological changes of the liver in the post-oligaemic phase of clinical haemorrhagic shock in dogs: correlation with improved survival rate and recovery. Free Radic Res Commun. 1989;6(1):29–38.
  • Kostopanagiotou GG, Kalimeris KA, Arkadopoulos N, Deferoxamine attenuates minor lung injury following surgical acute liver failure. Eur Respir J. 2009; 33(6):1429–1436.
  • Nicholson SC, Squier M, Ferguson DJ, Nagy Z, Westaby S, Evans RD. Effect of deferoxamine cardioplegia on ischemia-reperfusion injury in isolated rat heart. Ann Thorac Surg. 1997;63(4):1003–1011.
  • Pincemail J, Defraigne JO, Detry O, Franssen C, Meurisse M, Limet R. Ischemia-reperfusion injury of rabbit kidney: comparative effects of deferoxamine and N-acetylcysteine as antioxidants. Transplant Proc 2000;32(2):475–476.
  • Colet JM, Cetiner E, Hedlund BE, Muller RN. Assessment of microvascular integrity in the isolated perfused rat liver by contrast-enhanced MRI. Attenuation of reperfusion injury by conjugated deferoxamine. Magn Reson Med. 1996;36(5):753–757.
  • Doulias PT, Christoforidis S, Brunk UT, Galaris D. Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest. Free Radic Bio Med. 2003;35(7):719–728.
  • Kontoghiorghes GJ. Prospects for introducing deferiprone as potent pharmaceutical antioxidant. Front Biosci. (Elite Ed) 2009;1:161–178.

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