REFERENCES
- Hardison RC, Chui DHK, Giardine B, et al. Hb Var: a relational database of human hemoglobin variants and thalassemia mutations at the globin gene server. Hum Mutat. 2002;19(3):225–233 (http://globin.bx.psu.edu/hbvar).
- Patrinos GP, Giardine B, Riemer C, et al. Improvements in the HbVar human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res. 2004;32(Database issue):D537–D541 (http://globin.bx.psu.edu/hbvar).
- Shen SH, Slightom JL, Smithies O. A history of the human fetal globin gene duplication. Cell. 1981;26(2, Pt. 2):191–203.
- Slightom JL, Blechl AE, Smithies O. Human fetal Gγ- and Aγ-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes. Cell. 1980;21(3):627–638.
- Papadakis MN, Patrinos GP. Contribution of gene conversion in the evolution of the human γ-like globin gene family. Hum Genet. 1999;104(2):117–125.
- Huisman THJ, Harris H, Gravely M, The chemical heterogeneity of fetal hemoglobin in normal newborn infants and in adults. Mol Cell Biochem. 1977;17(1):45–55.
- Nakatsuji T, Ohba Y, Huisman THJ. Hb F-Yamaguchi (γ75Thr, γ80Asn, γ36Ala) is associated with Gγ-thalassemia. Am J Hematol. 16(2):189–192.
- Nakatsuji T, Lam H, Carver J, Huisman THJ. Hb F-Marietta or GγI80(EF4)Asp→Asn, observed in a Caucasian baby. Hemoglobin 1982;6(4):407–411.
- Kalamaras A, Chassanidis C, Samara M, The 5′ regulatory region of the human fetal globin genes is a gene conversion hot-spot. Hemoglobin. 2008;32(6):572–581.
- de Vooght KM, van Wijk R, Ploos van Amstel HK, van Solinge WW. Characterization of the –16C>G sequence variation in the promoters of both HBG1 and HBG2: convergent evolution of the human γ-globin genes. Blood Cells Mol Dis. 2007;39(1):70–74.
- Borg J, Georgitsi M, Aleporou-Marinou V, Kollia P, Patrinos GP. Genetic recombination as a major cause of mutagenesis in the human globin gene clusters. Clin Biochem. 2009;42(18):1839–1850.
- Chen JM, Cooper DN, Chuzhanova N, Férec C, Patrinos GP. Gene conversion: mechanisms, evolution and human disease. Nat Rev Genet. 2007;8(10):762–775
- Patrinos GP, Kollia P, Loutradi-Anagnostou A, Loukopoulos D, Papadakis MN. The Cretan type of non-deletional hereditary persistence of fetal hemoglobin (Aγ –158C>T) results from two independent gene conversion events. Hum Genet. 1998;102(6):629–634.
- Kollia P, Kalamaras A, Chassanidis C, Compound heterozygosity for the Cretan type of non-deletional hereditary persistence of fetal hemoglobin and β-thalassemia or Hb Sabine confirms the functional role of the Aγ –158 C>T mutation in γ-globin gene transcription. Blood Cells Mol Dis. 2008;41(3):263–264.
- Moradkhani K, Préhu C, Old J, Mutations in the paralogous human α-globin genes yielding identical hemoglobin variants. Ann Hematol. 2009;88(6):535–543.
- Giardine B, van Baal S, Kaimakis P, et al. HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update. Hum Mutat. 2007;28(2):206 (http://globin.bx.psu.edu/hbvar).