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Hemoglobin
international journal for hemoglobin research
Volume 35, 2011 - Issue 4
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Malignancies in β-Thalassemia Patients: First Description of Two Cases of Thyroid Cancer and Review of the Literature

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Pages 439-446 | Received 10 Jan 2011, Accepted 17 Mar 2011, Published online: 28 Jul 2011

REFERENCES

  • Rund D, Rachmilewitz E. β-Thalassemia. N Engl J Med. 2005;353(11):1135–1146.
  • Angelucci E, Barosi G, Camaschella C, Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders. Haematologica. 2008;93(5):741–752.
  • De Sanctis V. Multicentre study on prevalence of endocrine complications in thalassaemia major. Clin Endocrinol (Oxf). 1995;42:581–588.
  • Borgna-Pignatti C, Cappellini MD, De Stefano P, Survival and complications in thalassemia. Ann NY Acad Sci. 2005;1054:40–47.
  • Benetatos L, Alymara V, Vassou A, Bourantas KL. Malignancies in β-thalassemia patients: a single-center experience and a concise review of the literature. Int J Lab Hematol. 2008;30(2):167–172.
  • Wasniewska M, Raiola G, Teresa A, Gynecomastia disclosing diagnosis of Leydig cell tumour in a man with thalassemia, secondary hypogonadism and testis microlithiasis. Acta Biomed. 2009;80(3):286–288.
  • Thapa R, Pal PK, Mukhopadhyay M. β Thalassemia major and Hodgkin lymphoma. J Pediatr Hematol Oncol. 2009;31(6):462–463.
  • Karimi M, Giti R, Haghpanah S, Malignancies in patients with β-thalassemia major and β-thalassemia intermedia: a multicenter study in Iran. Pediatr Blood Cancer. 2009;53(6):1064–1067.
  • Naithani R, Chandra J, Bhattacharjee J, Peroxidative stress and antooxidant enzymes in children with β-thalassemia major. Pediatr Blood Cancer. 2006;46(7):780–785.
  • Toyokuni S. Role of iron in carcinogenesis: cancer as a ferrotoxic disease. Cancer Sci. 2009;100(1):9–16.
  • Huang X. Does iron have a role in breast cancer? Lancet Oncol. 2008;9(8):803–807.
  • Zacharski LR, Chow BK, Howes PS, Decreased cancer risk after iron reduction in patients with peripheral arterial disease: results from a randomized trial. J Natl Cancer Inst. 2008;100(14):996–1002.
  • Kaur P, Basu S. Transfusion-transmitted infections: existing and emerging pathogens. J Post-Grad Med. 2005;51(2):146–151.
  • Richardson DR. Potential of iron chelators as effective antiproliferative agents. Can J Physiol Pharmacol. 1997;75(10–11):1164–1180.
  • Jiao Y, Wilkinson J 4th, Di X, Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood. 2009;113(2):462–469.
  • Joosten E, Meeuwissen J, Vandewinckele H, Hiele M. Iron status and colorectal cancer in symptomatic elderly patients. Am J Med. 2008;121(12):1072–1077.
  • Borgna-Pignatti C, Vergine G, Lombardo T, Hepatocellular carcinoma in the thalassaemia syndromes. Br J Haematol. 2004;1241(1):114–117.
  • Otrock ZK, Shamseddine AI, Taher AT. Non-Hodgkin disease in β-thalassemia major. Am J Hematol. 2006;81(1):62–64.
  • Kontoghiorghes GJ (Guest Ed). Proceedings of the 17th International Conference on Chelation (ICOC) for the Treatment of Thalassemia, Cancer and Other Diseases Related to Metal and Free Radical Imbalance and Toxicity. November 2007, Shenzhen, China. Hemoglobin. 2009;33(5):283–397.
  • Restivo Pantalone G, Renda D, Valenza F, Hepatocellular carcinoma in patients with thalassemia syndromes: clinical characteristics and outcome in a long term centre experience Br J Haematol. 2010; 150(2):245–247.
  • Sherman SI. National Comprehensive Cancer Network, Clinical Practice Guidelines in Oncology, Thyroid Cancer V.1. 2009 (http://www.nccn.org/professionals/physician_gls/PDF/thyroid.pdf).
  • Pellegriti G, De Vathaire F, Scollo C, Papillary thyroid cancer incidence in the volcanic area of Sicily. J Natl Cancer Inst. 2009;101(22):1575–1583.
  • Moschovi M “Hodgkin’s disease in a child with sickle cell disease treated with hydroxyurea.” Pediatr Hematol Oncol 2001; 18 (6): 371–6.
  • Kaloterakis “Multiple myeloma in sickle cell syndromes” Haematologia 2001; 31 (2): 153–9.
  • Chehal A “Beta-thalassemia intermedia and non-hodgkin’s lymphoma” Hemoglobin 2002; 26 (3): 219–25.
  • Voskaridou “Chronic myeloid leukaemia with marked thrombocytosis in a patient with thalassaemia major: complete haematological remission under the combination of hydroxyurea and anagrelide” Br J Haematol 2002; 116 (1): 155–7.
  • Ricchi - “Asymptomatic cardiac lymphoma in a hepatitis C virus-positive thalassemic patient” Ital Heart J 2004; 5 (4): 302–4.
  • Mancuso - “Hepatocellular carcinoma on cirrhosis-free liver in a HCV-infercted thalassemic” Am J Hematol 2005; 78 (2): 158–9.
  • Jabr - “Beta-Thalassemia intermedia and Hodgkin lymphoma” Am J Hematol 2006; 81 (2): 151.
  • Maggio - “Hepatocellular carcinoma in patients with thalassemia syndromes: clinical characteristics and outcome in a long term single centre experience” Br J Haematol 2010; 150 (2): 245–7.

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