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Hemoglobin
international journal for hemoglobin research
Volume 36, 2012 - Issue 2
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Original Article

Prevalence and Molecular Analysis of β-Thalassemia in Adiyaman, Turkey

Ahmet GencVocational School of Health Services, Adıyaman University, Adıyaman, TurkeyCorrespondence[email protected]
,
Deniz Tastemir KorkmazVocational School of Health Services, Adıyaman University, Adıyaman, Turkey
,
Mehmet BuyukleylaBiology Department, Faculty of Sciences and Letters, Çukurova University, Adana, Turkey
&
Murat CelikerAdıyaman Obstetrics and Gynecology & Child Diseases Hospital, Adıyaman, Turkey
Pages 131-138 | Received 19 Oct 2011, Accepted 16 Dec 2011, Published online: 22 Feb 2012

REFERENCES

  • Tuzmen S, Schechter AN. Genetic diseases of hemoglobin: diagnostic methods for elucidating β-thalassemia mutations. Blood Rev. 2001;15(1):19–29.
  • Acemoglu H, Beyhun NE, Vancelik S, Polat H, Guraksin A. Thalassemia screening in a non-prevalent region of a prevalent country (Turkey): is it necessary? Public Health. 2008;122(6):620–624.
  • Tadmouri GO, Tüzmen S, Ozçelik H, Molecular and population genetic analyses of β-thalassemia in Turkey. Am J Hematol. 1998;57(3):215–220.
  • Altay Ç. Anormal hemoglobins in Turkey. Turk J Haematol. 2002;19(1):63–74.
  • Canatan D, Kose MR, Ustundag M, Haznedaroğlu D, Ozbaş S. Hemoglobinopathy control program in Turkey. Community Genet. 2006;9(2):124–126.
  • Başak AN. The molecular pathology of β-thalassemia in Turkey: the Boğaziçi University experience. Hemoglobin. 2007;31(3):233–241.
  • Yüreğir GT, Kılınç M, Ekerbiçer H, Bilaloğlu N, Tekin N. Screening of hemoglobinopathies in Kahramanmaraş, Turkey. Turk J Haematol. 2001;18(2):79–83.
  • Newton CR, Graham A, Heptinstall LE, Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res. 1989;17(7):2503–2516.
  • Bircan I, Sişli S, Güven A, Hemoglobinopathies in the district of Antalya, Turkey. Pediatr Hematol Oncol. 1993;10(3):289–291.
  • Tadmouri GO, Başak AN. β-Thalassemia in Turkey: A review of the clinical, epidemiological, molecular, and evolutionary aspects. Hemoglobin. 2001;25(2):227–239.
  • Gurbak M, Sivasli E, Coskun Y, Bozkurt AI, Ergin A. Prevalence and hematological characteristics of β-thalassemia trait in Gaziantep urban area, Turkey. Pediatr Hematol Oncol. 2006;23(5):419–425.
  • Yildiz S, Atalay A, Bagci H, Atalay EÖ. β-Thalassemia mutations in Denizli province of Turkey. Turk J Haematol. 2005;22(1):19–23.
  • Mendilcioglu I, Yakut S, Keser I, Prenatal diagnosis of β-thalassemia and other hemoglobinopathies in southwestern Turkey. Hemoglobin. 2011;35(1):47–55.
  • Atalay EO, Koyuncu H, Turgut B, High incidence of Hb D-Los Angeles [β121(GH4)Glu→Gln] in Denizli province, Aegean region of Turkey. Hemoglobin. 2005;29(4):307–310.
  • Altay Ç. The frequency and distribution pattern of β-thalassemia mutations in Turkey. Turk J Haematol. 2002;19(2):309–315.
  • Keser I, Sanlioglu AD, Manguoglu E, Molecular analysis of β-thalassemia and sickle cell anemia in Antalya. Acta Haemotol. 2004;111(4):205–210.
  • Ince HH, Ayyildiz O, Kalkanli S, Batun S, Muftuoglu E. Molecular basis of β-thalassemia mutations in Diyarbakir in the southeastern region of Turkey. Hemoglobin. 2003;27(4):275–278.
  • Güleşken S, Oren H, Vergin C, Mutational analysis of β-thalassemia cases from the Aegen region of Turkey using allele-specific oligonucleotide hybridization technique. Acta Haematol. 2000;1048(4):181–184.
  • Pan HF, Long GF, Li Q, Current status of thalassemia in minority populations in Guangxi, China. Clin Genet. 2007;71(5):419–426.
  • Laosombat V, Wongchanchailert M, Sattayasevana B, Wiriyasateinkul A, Fucharoen S. Clinical and hematological features of codon 17, a –T mutation of β-thalassemia in Thai. Eur J Haematol. 2001;66(2):126–129.
  • Svasti S, Hieu TM, Munkongdee T, Molecular analysis of β-thalassemia in south Vietnam. Am J Hematol. 2002;71(2):85–88.
  • Hardison RC, Chui DHK, Giardine B, et al. HbVar: a relational database of human hemoglobin variants and thalassemia mutations at the globin gene server. Hum Mutat. 2002;19(3):225–233 (http://globin.cse.psu.edu).
  • Patrinos GP, Giardine B, Riemer C, et al. Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res. 2004;32(Database issue): D537-D541 (http://globin.cse.psu.edu).
  • Cürük MA, Arpaci A, Atilla G, Genetic heterogeneity of β-thalassemia at Çukurova in southern Turkey. Hemoglobin. 2001;25(2)241–245.
  • Tadmouri GO, Tüzmen S, Başak AN. Rare β-thalassemia mutation in a Turkish patient: FSC-36/37(–T). Hum Biol. 1997;69(2):263–267.
  • Pehlivan S, Okan V, Guler E, Thalassemia mutations in Gaziantep, Turkey. African J Biotechnol. 2010;9:1255–1259.
  • Ince HH, Ayyildiz O, Kalkanli S, Batun S, Muftuoglu E. Molecular basisi of β-thalassemia mutations in Diyarbakir in the southeastern region of Turkey. Hemoglobin. 2003;27(4):275–278.
  • Papachatzopoulou A, Kourakli A, Stavrou EF, Region-specific genetic heterogeneity of HBB mutation distribution in southwestern Greece. Hemoglobin. 2010;(34(4):333–342.
  • Samara M, Chiotoglou I, Kalamaras A, Large-scale population genetic analysis for hemoglobinopathies reveals different mutation spectra in central Greece compared to the rest of the country. Am J Hematol. 2007;82(7):634–636.
  • Radmilovic M, Zukic B, Stankovic B, Thalassemia syndromes in Serbia: an update. Hemoglobin. 2010;34(5):477–485.

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