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Hemoglobin
international journal for hemoglobin research
Volume 36, 2012 - Issue 5
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Short Communication

Unmasking Hb Paksé (codon 142, TAA>TAT, α2) and its Combinations in Patients also Carrying Hb Constant Spring (codon 142, TAA>CAA, α2) in Northern Thailand

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Pages 491-496 | Received 22 Mar 2012, Accepted 01 May 2012, Published online: 19 Sep 2012

REFERENCES

  • Lemmens-Zygulska M, Eigel A, Helbig B, Sanguansermsri T, Horst J, Flatz G. Prevalence of α-thalassemias in northern Thailand. Hum Genet. 1996;98(3):345–347.
  • Higgs DR, Vickers MA, Wilkie AOM, Pretorius IM, Jarman AP, Weatherall DJ. A review of the molecular genetics of the human α-globin gene cluster. Blood. 1989;73(5):1081–1104.
  • Kazazian HH Jr. The thalassemia syndromes: molecular basis and prenatal diagnosis in 1990. Semin Hematol. 1990;27(3):209–228.
  • Fucharoen S, Winichagoon P. Hemoglobinopathies in Southeast Asia. Hemoglobin. 1987;11(1):65–88.
  • Laig M, Pape M, Hundrieser J, . The distribution of the Hb Constant Spring gene in Southeast Asian populations. Hum Genet. 1990;84(2):188–190.
  • Pootrakul P, Winichagoon P, Fucharoen S, Pravatmuang P, Piankijagum A, Wasi P. Homozygous Haemoglobin Constant Spring: a need for revision of concept. Hum Genet. 1981;59(3):250–255.
  • Fucharoen S, Winichagoon P, Pootrakul P, Piankijagum A, Wasi P. Differences between two types of Hb H disease, α-thalassemia 1/α-thalassemia 2 and α-thalassemia 1/Hb Constant Spring. Birth Defects Orig Artic Ser. 1987;23(5A):309–315.
  • Tangvarasittichai O, Jeenapongsa R, Sitthiworanan C, Sanguansermsri T. Laboratory investigations of Hb Constant Spring. Clin Lab Haematol. 2005;27(1):47–49.
  • Viprakasit V, Tanphaichitr VS, Pung-Amritt P, . Clinical phenotypes and molecular characterization of Hb H-Paksé disease. Haematologica. 2002;87(2):117–125.
  • Singsanan S, Fucharoen G, Savongsy O, Sanchaisuriya K, Fucharoen S. Molecular characterization and origins of Hb Constant Spring and Hb Paksé in Southeast Asian populations. Ann Hematol. 2007;86(9):665–669.
  • Pornprasert S, Phusua A, Suanta S, Saetung R, Sanguansermsri T. Detection of α-thalassemia-1 Southeast Asian type using real-time gap-PCR with SYBR Green1 and high resolution melting analysis. Eur J Haematol. 2008;80(6):510–514.
  • Fucharoen S, Sanchaisuriya K, Fucharoen G, Panyasai S, Devenish R, Luy L. Interaction of Hemoglobin E and several forms of α-thalassemia in Cambodian families. Haematologica. 2003;88(10):1092–1098.
  • Waye JS, Eng B, Patterson M, Chui DHK, Olivieri NF. Identification of a novel termination codon mutation (TAA→TAT, Term→Tyr) in the α2 globin gene of a Laotian girl with Hemoglobin H disease. Blood. 1994;83(11):3418–3420.
  • Pichanun D, Munkongdee T, Klamchuen S, . Molecular screening of the Hbs Constant Spring (codon 142, TAA>CAA, α2) and Paksé (codon 142, TAA>TAT, α2) mutations in Thailand. Hemoglobin. 2010;34(6):582–586.
  • Charoenkwan P, Taweephon R, Sae-Tung R, Thanarattanakorn P, Sanguansermsri T. Molecular and clinical features of Hb H disease in northern Thailand. Hemoglobin. 2005;29(2):133–140.
  • Sanchaisuriya K, Fucharoen G, Fucharoen S. Hb Paksé [(α2) codon 142 (TAA→TAT or Term→Tyr)J in Thai patients with EABart’s disease and Hb H disease. Hemoglobin. 2002;26(3):227–235.
  • Kanavakis E, Papassotiriou I, Karagiorga M, . Phenotypic and molecular diversity of Haemoglobin H disease: a Greek experience. Br J Haematol. 2000;111(3):915–923.
  • Kattamis C, Tzotzos S, Kanavakis E, Synodinos J, Metaxotou-Mavrommati A. Correlation of clinical phenotype to genotype in Haemoglobin H disease. Lancet. 1988;1(8583):442–444.
  • Papassotiriou I, Traeger-Synodinos J, Kanavakis E, Karagiorga M, Stamoulakatou A, Kattamis C. Erythroid marrow activity and Hemoglobin H levels in Hemoglobin H disease. J Pediatr Hematol Oncol. 1998;20(6):539–544.

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