REFERENCES
- Madigan C, Malik P. Pathophysiology and therapy for haemoglobinopathies. Part I: sickle cell disease. Expert Rev Mol Med. 2006;8(9):1–23.
- Kulozik AE, Wainscoat JS, Serjeant GR, . Geographical survey of βS-globin gene haplotypes: evidence for an independent Asian origin of the sickle-cell mutation. Am J Hum Genet. 1986; 39(2):239–244.
- Rees DC, Williams TN, Gladwin MT. Sickle-cell disease. Lancet 2010;376(9757):2018–2031.
- Central Statistical Organization. Statistical Year Book 2009. Republic of Yemen, Sana’a: Ministry of Planning and International Cooperation, 2010.
- Hay SI, Guerra CA, Tatem AJ, Noor AM, Snow RW. The global distribution and population at risk of malaria: past, present, and future. Lancet Infect Dis. 2004;4(6):327–336.
- Williams TN. Human red blood cell polymorphisms and malaria. Curr Opin Microbiol. 2006; 9(4):388–394.
- Al-Nood H, Al-Ismail S, King L, May A. Prevalence of the sickle cell gene in Yemen: a pilot study. Hemoglobin. 2004;28(4):305–315.
- Jastaniah W. Epidemiology of sickle cell disease in Saudi Arabia. Ann Saudi Med. 2011;31(3):289–293.
- Pandmos MA, Roberts GT, Sackey K, . Two different forms of homozygous sickle cell disease occur in Saudi Arabia. Br J Haematol. 1991;79(1):93–98.
- Al-Ghazaly J, Al-Selwi AH, Abdullah M, Al-Jahafi AK, Al-Dubai W, Al-Hashdi A. Pattern of haematological diseases diagnosed by bone marrow examination in Yemen: a developing country experience. Clin Lab Haematol. 2006;28(6):376–381.
- Gaston M, Rosse WF. The cooperative study of sickle cell disease: review of study design and objectives. Am J of Pediatr Hematol/Oncol. 1982;4(2):197–201.
- Miller ST, Sleeper LA, Pegelow CH, . Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med. 2000;342(2) 83–89.
- Milner PF, Kraus AP, Sebes JI, . Sickle cell disease as a cause of osteonecrosis of the femoral head. N Eng J Med. 1991;325(21):1476–1481.
- Gill FM, Sleeper LA, Weiner SJ, . Clinical events in the first decade in a cohort of infants with sickle cell disease. Blood. 1995;86(2):776–783.
- Emond AM, Holman R, Hayes RJ, Serjeant GR. Priapism and impotence in homozygous sickle cell disease. Arch Intern Med. 1980;140(11):1434–1437.
- Koshy M, Entsuah R, Koranda A, . Leg ulcers in patients with sickle cell disease. Blood. 1989; 74(4):1403–1408.
- Dacie JV, Lewis SM, Eds. Basic hematological techniques. Practical Haematology, 7th ed. Edinburgh: Churchill Livingstone. 1991:61–63.
- Dacie JV, Lewis SM, Eds. Investigation of the abnormal haemoglobins and thalassaemia (with White JM, Marsh GW). Practical Hematology, 7th ed. Edinburgh: Churchill Livingstone. 1991:234–236.
- Bishop ML, Duben-Enelkrik JL, Fody EP, Eds. Clinical Chemistry: Principles, Procedures, Correlations, 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2000.
- Al-Ghazaly J. Pattern of adult leukemias at Al-Jomhori Educational Hospital, Sana’a, Yemen. Turk J Haematol. 2005;22(1):31–35.
- Al-Ghazaly J, Al-Dubai W, Al-Jahafi AK, Abdullah M, Al-Hashdi A. Cyclosporine monotherapy for severe aplastic anemia: a developing country experience. Ann Saudi Med. 2005;25(5):375–379.
- Al-Gazali L, Hamamy H, Al-Arrayad S. Genetic disorders in the Arab world. BMJ. 2006; 333(7573):831–834.
- Jurdi R, Saxena PC. The prevalence and correlates of consanguineous marriages in Yemen: similarities and correlates with other Arab countries. J Biosoc Sci. 2003;35(1):1–13.
- Platt OS, Brambilla DJ, Rosse WF, . Mortality in sickle cell disease, life expectancy and risk factors for early death. N Eng J Med. 1994;330(23):1639–1644.
- Adekile A, Al-Kandari M, Haider M, Rajaa M, D’Souza M, Sukumaran J. Hemoglobin F concentration as a function of age in Kuwaiti sickle cell disease patients. Med Princ Pract. 2007;16(4):286–290.
- Platt OS, Thorington BD, Brambilla DJ, . Pain in sickle cell disease. Rates and risk factors. N Eng J Med. 1991;325(1):11–16.
- Booth C, Inusa B, Obaro SK. Infection in sickle cell disease: a review. Int J Infect Dis. 2010;14(1):e2–e12.
- Halasa NB, Shankar SM, Talbot TR, . Incidence of invasive pneumococcal disease among individuals with sickle cell disease before and after the introduction of the pneumococcal conjugate vaccine. Clin Infect Dis. 2007;44(11):1428–1433.
- Almeida A, Roberts I. Bone involvement in sickle cell disease. Br J Haematol. 2005;129(4):482–490.
- Makani J, Komba AN, Cox SE, . Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization. Blood. 2010;115(2):215–220.
- Serjeant GR. The geography of sickle cell disease: opportunities for understanding diversity. Ann Saudi Med. 1994;14(2):237–246.
- Wali YA, Al-Lamli Z, Hussein SS, . Splenic function in Omani children with sickle cell disease: correlation with severity index, hemoglobin phenotype, iron status, and α-thalassemia trait. Pediatr Hematol Oncol. 2002;19(7):491–500.
- Inati A, Jradi O, Tarabay H, . Sickle cell disease: the Lebanese experience. Int J Lab Hematol. 2007;29(6):399–408.
- Tyagi S, Choudhry VP, Saxena R. Subclassification of Hb S syndrome: is it necessary? Clin Lab Haematol. 2003;25(6):377–381.
- Serjeant GR, Sommereux AM, Stevenson M. Comparison of sickle cell-β-thalassaemia with homozygous sickle cells. Br J Haematol. 1979;41(1):83–93.
- Webb DKH, Darby JS, Dunn DT. Gallstones in Jamaican children with homozygous sickle cell disease. Arch Dis Child. 1989;64(5):693–696.
- Bond LR, Hatty SR, Horn MEC, Dick M. Gall stones in sickle cell disease in the United Kingdom. BMJ. 1987;295(6592):234–236.
- Al-Suleiman A, Aziz G, Bagshia M, El Liathi S, Homrany H. Acute chest syndrome in adult sickle cell disease in eastern Saudi Arabia. Ann Saudi Med. 2005;25(1):53–55.
- Alabdulaali MK. Sickle cell disease patients in eastern province of Saudi Arabia suffer less severe acute chest syndrome than patients with African haplotypes. Ann Thorac Med. 2007;2(4):158–162.
- Akinyoola AL, Adediran IA, Asaleye CM. Avascular necrosis of the femoral head in sickle cell disease in Nigeria: a retrospective study. Niger Postgrad Med J. 2007;14(3):217–220.
- Hoppe C. Defining stroke risk in children with sickle cell anaemia. Br J Haematol. 2005;128(6):751–766.
- Switzer JA, Hess DC, Nichols FT, Adams RJ. Pathophysiology and treatment of stroke in sickle-cell disease: present and future. Lancet Neurol. 2006;5(6):501–512.
- Perrine RP, Pembrey ME, John P, Perrine S, Shoup F. Natural history of sickle cell disease in Saudi Arabs. A study of 270 subjects. Ann Intern Med. 1978;88(1):1–6.
- Serjeant GR. Sickle-cell disease. Lancet. 1999;350(9079):725–730.
- Akinsheye I, Alsultan A, Solovieff N, . Fetal hemoglobin in sickle cell anemia. Blood. 2011;118(1):19–27.
- El-Hazmi MA, Warsy AS. Comparative study of hematological parameters in children suffering from SCA from different regions from Saudi Arabia. J Trop Pediatr. 2001;47(3):136–141.
- El-Hazmi MAF, Warsy AS. Pattern for α-thalassaemia in Yemeni sickle-cell-disease patients. East Mediterr Health J. 1999;5(6):1159–1164.
- Bain BJ. Neonatal/newborn haemoglobinopathy screening in Europe and Africa. J Clin Pathol. 2009;62(1):53–56.
- Alswaidi FM, O’Brien SJ. Premarital screening programmes for haemoglobinopathies, HIV and hepatitis viruses: review and factors affecting their success. J Med Screen. 2009;16(1):22–28.