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Hemoglobin
international journal for hemoglobin research
Volume 38, 2014 - Issue 2
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Research Article

Assessment of Iron Overload in Very Young Children with Limited Thalassemia Care Resources in South China

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Pages 119-126 | Received 01 Apr 2013, Accepted 24 Sep 2013, Published online: 07 Feb 2014

References

  • Rund D, Rachmilewitz E. β-Thalassemia. N Engl J Med. 2005;353(11):1135–1146
  • Delea TE, Edelsberg J, Sofrygin O, et al. Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review. Transfusion. 2007;47(10):1919–1929
  • Olivieri NF, Nathan DG, MacMillan JH, et al. Survival in medically treated patients with homozygous β-thalassemia. N Engl J Med. 1994;331(9):574–578
  • Neufeld EJ. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions. Blood. 2006;107(9):3436–3441
  • Telfer P, Coen PG, Christou S, et al. Survival of medically treated thalassemia patients in Cyprus. Trends and risk factors over the period 1980–2004. Haematologica. 2006;91(9):1187–1192
  • Modell B, Khan M, Darlison M, et al. Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2008;10(1):42–46
  • Kontoghiorghes GJ. The proceedings of the 17th International Conference on Chelation: application of effective chelation therapies in iron loading and non iron loading conditions, and the gap in the prevention and treatment policies on thalassemia between developed and developing countries. Hemoglobin. 2009;33(5):283–286
  • Weatherall DJ. The challenge of haemoglobinopathies in resource-poor countries. Br J Haematol. 2011;154(2):736–744
  • Li CG, Li CF, Li Q, Li M. Thalassemia incidence and treatment in China with special reference to Shenzhen City and Guangdong Province. Hemoglobin. 2009;33(5):296–303
  • Liu S, Griffiths SM. From economic development to public health improvement: China faces equity challenges. Public Health. 2011;125(10):669–674
  • Hutubessy RC, Hanvoravongchai P, Edejer TT; Asian MRI Study Group. Diffusion and utilization of magnetic resonance imaging in Asia. Int J Technol Assess Health Care. 2002;18(3):690–704
  • Au WY, Lee V, Lau CW, et al. A synopsis of current care of thalassaemia major patients in Hong Kong. Hong Kong Med J. 2011;17(4):261–266
  • Kirk P, He T, Anderson LJ, et al. International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers. J Magn Reson Imaging. 2010;32(2):315–319
  • Lam WWM, Au WY, Chu WWC, et al. One stop measurement of iron deposition in anterior pituitary, liver and heart in thalassemia patients. J Magn Reson Imaging. 2008;28(1):29–33
  • Au WY, Lam WWM, Chu W, et al. A T2* magnetic resonance imaging (MRI) study of pancreatic iron overload in thalassemia major. Haematologica. 2007;93(1):116–119
  • Au WY, Lam WWM, Chu WWC, et al. A cross-sectional MRI assessment of organ specific hemosiderosis in 180 thalassemia major patients in Hong Kong. Haematologica. 2008;93(5):784–786
  • Tanner MA, He T, Westwood MA, et al. Multi-center validation of the transferability of the magnetic resonance T2* technique for the quantification of tissue iron. Haematologica. 2006;91(10):1388–1391
  • Anderson LJ, Westwood MA, Holden S, et al. Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance. Br J Haematol. 2004;127(3):348–355
  • Ghugre NR, Enriquez CM, Gonzalez I, et al. MRI detects myocardial iron in the human heart. Magn Reson Med. 2006;56(3):681–686
  • Noetzli LJ, Panigrahy A, Mittelman SD, et al. Pituitary iron and volume predict hypogonadism in transfusional iron overload. Am J Hematol. 2012;87(2):167–171
  • Noetzli LJ, Mittelman SD, Watanabe RM, et al. Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol. 2012;87(2):155–160
  • Carpenter JP, He T, Kirk P, et al. On T2* magnetic resonance and cardiac iron. Circulation. 2011;123(14):1519–1528
  • Lee VS, Resnick D, Bundy JM, et al. Cardiac function: MR evaluation in one breath hold with real-time true fast imaging with steady-state precession. Radiology. 2002;222(3):835–842
  • Peng X. China’s demographic history and future challenges. Science. 2011;333(6042):581–587
  • Sun Q, Liu X, Meng Q, et al. Evaluating the financial protection of patients with chronic disease by health insurance in rural China. Int J Equity Health. 2009;8(2):42–47
  • Wu KH, Chang JG, Ho YJ, et al. Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with β-thalassemia major. Hemoglobin. 2006;30(2):251–256
  • Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001;22(23):2171–2179
  • Chouliaras G, Berdoukas V, Ladis V, et al. Impact of magnetic resonance imaging on cardiac mortality in thalassemia major. J Magn Reson Imaging. 2011;34(1):56–59
  • Pennell DJ. T2* magnetic resonance and myocardial iron in thalassemia. Ann NY Acad Sci. 2005;1054:373–378
  • Yip WC, Hsiao W, Meng Q, et al. Realignment of incentives for health-care providers in China. Lancet. 2010;375(9720):1120–1130
  • Berdoukas V, Nord A, Carson S, et al. Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age. Am J Hematol. 2013;88(11):E283–E285
  • Gulati R, Bhatia V, Agarwal SS. Early onset of endocrine abnormalities in β-thalassemia major in a developing country. J Pediatr Endrocinol Metab. 2000;13(6):651–656
  • De Sanctis V, Eleftheriou A, Malaventura C. Prevalence of endocrine complications and short stature in patients with thalassaemia major: a multicenter study by the Thalassaemia International Federation (TIF). Pediatr Endocrinol Rev. 2004;2(Suppl 2):249–255
  • Farmaki K, Angelopoulos N, Anagnostopoulos G, et al. Effect of enhanced iron chelation therapy on glucose metabolism in patients with β-thalassaemia major. Br J Haematol. 2006;134(4):438–444
  • Hardee K. Implications of China’s one-child policy. Int Demogr. 1984;3(5):11–12
  • Viprakasit V, Lee-Lee C, Chong QT, et al. A. Iron chelation therapy in the management of thalassemia: the Asian perspectives. Int J Hematol. 2009;90(4):435–445

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