Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 39, 2015 - Issue 2
327
Views
8
CrossRef citations to date
0
Altmetric
Short Communication

Screening for Thalassemia Carriers in Populations with a High Rate of Iron Deficiency: Revisiting the Applicability of the Mentzer Index and the Effect of Iron Deficiency on Hb A2 Levels

, , &
Pages 141-143 | Received 12 Aug 2014, Accepted 26 Oct 2014, Published online: 25 Mar 2015

References

  • Mentzer WC Jr. Differentiation of iron deficiency from thalassaemia trait. Lancet. 1973;1(7808):882
  • England JM, Fraser PM. Differentiation of iron deficiency from thalassaemia trait by routine blood count. Lancet. 1973;1(7801):449–452
  • Green R, King R. A new red cell discriminant incorporating volume dispersion for differentiating iron deficiency from thalassemia minor. Blood Cells. 1989;15(3):481–491
  • Shine I, Lal S. A strategy to detect β thalassaemia minor. Lancet. 1977;1(8013):692–694
  • Srivastava PC, Bevington JM. Iron deficiency and-or thalassaemia trait. Lancet. 1973;1(7807):832
  • Steiner J, Marti HR, Dean D. Decreased Hemoglobin A2 concentration in iron deficiency anemia. Acta Haematol. 1971;45(2):77–81
  • Passarello C, Giambona A, Cannata M, et al. Iron deficiency does not compromise the diagnosis of high Hb A2 β thalassemia trait. Haematologica. 2012;97(3):472–473
  • Galanello R, Ruggeri R, Addis M, et al. Hemoglobin A2 in iron deficient β-thalassemia heterozygotes. Hemoglobin. 1981;5(6):613–618
  • Harthoorn-Lasthuizen EJ, Lindemans J, Langenhuijsen MM. Influence of iron deficiency anaemia on Haemoglobin A2 levels: Possible consequences for β-thalassaemia screening. Scand J Clin Lab Invest. 1999;59(1):65–70
  • Madan N, Sikka M, Sharma S, Rusia U. Phenotypic expression of Hemoglobin A2 in β-thalassemia trait with iron deficiency. Ann Hematol. 1998;77(3):93–96
  • Abolghasemi H, Amid A, Zeinali S, et al. Thalassemia in Iran: Epidemiology, prevention, and management. J Pediatr Hematol Oncol. 2007;29(4):233–238
  • Balarajan Y, Ramakrishnan U, Ozaltin E, et al. Anaemia in low-income and middle-income countries. Lancet. 2011;378(9809):2123–3215
  • Giordano PC. Strategies for basic laboratory diagnostics of the hemoglobinopathies in multi-ethnic societies: Interpretation of results and pitfalls. Int J Lab Hematol. 2013;35(5):465–479
  • Steinberg MH, Nagel RL. Hemoglobins of embryo, fetus, and adult. In: Steinberg MH, Forget BG, Higgs DR, Weatherall DJ, Eds. Disorders of Hemoglobin Genetics, Pathophysiology, and Clinical Management, 2nd ed. Cambridge, UK: Cambridge University Press. 2009:119–135
  • Ben-Bassat I, Mozel M, Ramot B. Globin synthesis in iron-deficiency anemia. Blood. 1974;44(4):551–555
  • Steinberg MH, Adams JG 3rd. Hemoglobin A2: Origin, evolution, and aftermath. Blood. 1991;78(9):2165–2177

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.