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Hemoglobin
international journal for hemoglobin research
Volume 40, 2016 - Issue 2
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A Novel β-Globin Chain Hemoglobin Variant, Hb Allentown [β137(H15)Val→Trp (GTG>TGG) HBB: c.412_413delinsTG, p.Val138Trp], Associated with Low Oxygen Saturation, Intermittent Aplastic Crises and Splenomegaly

Anderson B. Collier IIIDepartment of Pediatrics, Division of Pediatric Hematology-Oncology, University of Mississippi Medical Center, Jackson, Mississippi, USA Correspondence[email protected]
,
Lea M. CoonDepartments of Laboratory Medicine and Pathology, Hematopathology, Mayo Clinic, Rochester, Minnesota, USA
,
Philip MonteleoneDepartment of Pediatrics, Lehigh Valley Health Network, Allentown, Pennsylvania, USA
,
Samuel UmaruDepartment of Pediatrics, Lehigh Valley Health Network, Allentown, Pennsylvania, USA
,
Kenneth C. SwansonDepartments of Laboratory Medicine and Pathology, Hematopathology, Mayo Clinic, Rochester, Minnesota, USA
,
James D. HoyerDepartments of Laboratory Medicine and Pathology, Hematopathology, Mayo Clinic, Rochester, Minnesota, USA
&
Jennifer L. OliveiraDepartments of Laboratory Medicine and Pathology, Hematopathology, Mayo Clinic, Rochester, Minnesota, USA
show all
Pages 130-133 | Received 28 Aug 2015, Accepted 21 Oct 2015, Published online: 17 Dec 2015

References

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  • Moo-Penn WF, Jue DL, Johnson MH, et al. Hemoglobin Brockton [β138(H16)Ala→Pro]: An unstable variant near the C-terminus of the β-subunits with normal oxygen-binding properties. Biochemistry. 1988;27(20):7614–7619
  • Negri Arjona S, Maldonado Eloy-Garcia J, Molchanova TP, et al. Hb Brockton [α2β2138(H16)Ala→Pro] observed in a Spanish girl. Hemoglobin. 1992;16(6):511–514
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