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Hemoglobin
international journal for hemoglobin research
Volume 23, 1999 - Issue 1
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BriefNote Article

Characterization of Hb djeifa [β98(FG5)Val→Ala] by DNA sequencing in a French caucasian family

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Pages 73-77 | Received 31 Mar 1998, Accepted 23 Sep 1998, Published online: 05 Aug 2009

References

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  • Gacon G., Krishnamoorthy R., Wajcman H., Labie D., Tapon J., Cosson A. Hemoglobin Djelfa β98(FG5)Val→Ala: isolation and functional properties of the heme saturated form. Biochim. Biophys. Acta 1977; 490: 156–163
  • Bird A. R., Elliott T., Wilson J. B., Webber B. B., Hu H., Kutlar A., Kutlar F., Huisman T. H. J. Two rare unstable p chain variants, Hb Mozhaisk or α2β292 (F8)His→Arg and Hb Djelfa or α2β298(FG5)Val→Ala, each being observed for the second time. Hemoglobin 1989; 13: 193–197
  • Lacan P., Kister J., Francina A., Souillet G., Galacteros F., Delaunay J., Wajcman H. Hemoglobin Debrousse ‘β96(FG3)Leu→Pro’: a new unstable hemoglobin with twofold increased oxygen affinity. Am. J. Hematol. 1996; 51: 276–281
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  • Williamson D., Perry D. J., Brown K., Langdown J. V. Compound heterozygosity for two β chain variants: Hb S ‘β6(A3)Glu→Val’ and the high affinity variant Hb San Diego ‘βl09(G11)Val→Met’. Hemoglobin 1995; 19: 27–32
  • Kister J., Poyart C., Edelstein S. J. An expanded two‐state allosteric model for interactions of human hemoglobin A with nonsaturating concentrations of 2,3‐diphosphoglycerate. J. Biol. Chem. 1987; 262: 12085–12091
  • Carrell R. W., Kay R. A simple method for the detection of unstable haemoglobins. Br. J. Haematol. 1972; 23: 615–619
  • Rahbar S., Asmerom Y. Rapid HPLC techniques for globin chain synthesis studies. Hemoglobin 1989; 13: 475–487
  • Witkowska H. E., Bitsch F., Shackleton C. H. L. Expediting rare variant hemoglobin characterization by combined HPLC/electrospray mass spectrometry. Hemoglobin 1993; 17: 227–242
  • Jelkmann W., Bauer C. What is the best method to remove 2,3‐diphosphoglycerate from hemoglobin?. Anal. Biochem. 1976; 75: 382–388

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