Shear-induced APAP de-agglomeration

References

• DesRosiers Lachiver E, Abatzoglou N, Cartilier L, Simard JS. (2006). Agglomeration tendency in dry pharmaceutical granular systems. Eur J Pharm Biopharm, 64:193–9.
   PubMed Web of Science ®Google Scholar
• De Villiers MM, Van der Watt JG. (1989). Interactive mixing between agglomerated drug particles and coarse carrier particles. Drug Dev Ind Pharm, 15:2055–61.
   Web of Science ®Google Scholar
• De Villiers MM, Van der Watt JG. (1994). Measurement of mixture homogeneity and dissolution to predict the degree of drug agglomerate breakdown achieved through powder mixing. Pharm Res, 11:1557–61.
   PubMed Web of Science ®Google Scholar
• Saunders R. (1991). The effect of particle agglomeration in pharmaceutical preparations. Statistician 40:77–86.
   Google Scholar
• Thiel, WJ, Nguyen LT, Sberna FJ. (1986). Content uniformity of microdose tablets (dosage 1 microgram – 10 mg) produced by fluid bed granulation of interactive mixtures. J Pharm Pharmacol, 38:335–43.
   PubMed Web of Science ®Google Scholar
• Stewart PJ, Zhao FY. (2005). Understanding agglomeration of indomethacin during the dissolution of micronised indomethacin mixtures through dissolution and de-agglomeration modeling approaches. Eur J Pharm Biopharm, 59:315–23.
   PubMed Web of Science ®Google Scholar
• Swanepoel E, Liebenberg W, De Villiers MM, Dekker TG. (2000). Dissolution properties of piroxicam powders and capsules as a function of particle size and the agglomeration of powders. Drug Dev Ind Pharmacy, 26:1067–76.
   PubMed Web of Science ®Google Scholar
• De Villiers MM, Van der Watt JG. (1990). Dissolution rate as measurement of the de-aggregation of furosemide agglomerates during an interactive mixing process. Drug Dev Ind Pharm, 16:1391–7.
   Web of Science ®Google Scholar
• Muzzio FJ, Alexander A. (2005). Scale up of powder-blending operations. Pharm Technol, 29:34–42.
   Google Scholar
• Van der Watt JG, De Villiers MM. (1995). Effect of mixing variables on the dissolution properties of direct compression formulations of furesomide. Drug Dev Ind Pharm, 21:2047–56.
   Web of Science ®Google Scholar
• Muzzio FJ, Llusa M, Goodridge CL, Duong NH, Shen E. (2008). Evaluating the mixing performance of a ribbon blender. Powder Technol, 186:247–54.
   Web of Science ®Google Scholar
• Sudah OS, Coffin-Beach D, Muzzio FJ. (2002). Effects of blender rotational speed and discharge on the homogeneity of cohesive and free-flowing mixtures. Int J Pharm, 247:57–68.
   PubMed Web of Science ®Google Scholar
• Kale K, Hapgood K, Stewart P. (2009). Drug agglomeration and dissolution – what is the influence of powder mixing? Eur J Pharm Biopharm, 72:156–64.
   PubMed Web of Science ®Google Scholar
• Cartillier LH, Moes AJ. (1989). Effect of drug agglomerates upon the kinetics of mixing of low dosage cohesive powder mixtures. Drug Dev Ind Pharm, 12:1911–31.
   Google Scholar
• Llusa M, Sturm K, Sudah O, Stamato H, Goldfarb DJ, Ramachandruni H, et al. (2009). Effect of high shear blending protocols and blender parameters on the degree of API agglomeration in solid formulations. Ind Eng Chem Res, 48:93–101.
   Web of Science ®Google Scholar
• De Villiers MM. (1997). Description of the kinetics of the deagglomeration of drug particle agglomerates during powder mixing. Int J Pharm, 151:1–6.
   Web of Science ®Google Scholar
• Llusa M, Mehrotra A., Faqih A, Levin M, Muzzio FJ. (2007). Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate. Int J Pharm, 336:284–91.
   PubMedGoogle Scholar
• El-Hagrasy AS, Delgado-Lopez M, Drennen JK. (2006). A process analytical technology approach to near-infrared process control of pharmaceutical powder blending: Part II: Qualitative near-infrared models for prediction of blend homogeneity. J Pharm Sci, 95:407–21.
   PubMed Web of Science ®Google Scholar
• Shah NH, Phuapradit W, Bachynsky M, Infeld MH, Malick AW, et al. (1994). High energy ordered mixture for improving the dissolution rate of sparingly soluble compounds. Drug Dev Ind Pharm, 20:873–88.
   Web of Science ®Google Scholar
• Perrut M, Jung J, Leboeuf F. (2005). Enhancement of dissolution rate of poorly-soluble active ingredients by supercritical fluid processes. Part I: Micronization of neat particles. Int J Pharm, 288:3–10.
   PubMed Web of Science ®Google Scholar
• Kurfeβ D, Hinrichsen H, Zimmermann I. (2005). Statistical model of the powder flow regulation by nanomaterials. Powder Technol, 159:63–70.
   Google Scholar
• Jones R, Pollock HM, Geldart D, Verlinden A. (2003). Inter-particle forces in cohesive powders studied by AFM: Effects of relative humidity, particle size and wall adhesion. Powder Technol, 132:196–210.
   Web of Science ®Google Scholar
• DesRosiers Lachiver E, Abatzoglou N, Cartilier L, Simard JS. (2006). Insights into the role of electrostatic forces on the behavior of dry pharmaceutical particulate systems. Pharm Res, 23:997–1007.
   PubMed Web of Science ®Google Scholar
• Staniforth JN, Rees JE. (1982). Electrostatic charge interactions in ordered powder mixes. J Pharm Pharmacol, 34:69.
   PubMed Web of Science ®Google Scholar
• Schönert K, Eichas K, Niermöller F. (1996). Charge distribution and state of agglomeration after tribocharging fine particulate materials. Powder Technol, 86:41–7.
   Web of Science ®Google Scholar
• Buckton G. (1997). Characterisation of small changes in the physical properties of powders of significance for dry powder inhaler formulations. Adv Drug Deliv Rev, 26:17–27.
   PubMed Web of Science ®Google Scholar
• Dickhoff BHJ, de Boer AH, Lambregts D, Frijlink HW. (2005). The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation. Eur J Pharm Biopharm, 59:197–205.
   PubMed Web of Science ®Google Scholar
• Jonat S, Hasenzahl S, Drechsler M, Albers P, Wagner KG, Schmidt PC. (2004). Investigation of compacted hydrophilic and hydrophobic colloidal silicon dioxides as glidants for pharmaceutical excipients. Powder Technol, 141:31–43.
   Web of Science ®Google Scholar
• Meyer K, Zimmermann I. (2004). Effect of glidants in binary powder mixtures. Powder Technol, 139:40–54.
   Web of Science ®Google Scholar
• Malmqvist K, Nystrom C. (1984). Studies on direct compression of tablets. Part 8. Sieve classification method for the determination of agglomerates and the distribution of fine particles in ordered mixing. Acta Pharm Suec, 21:9–20.
   Google Scholar