204
Views
9
CrossRef citations to date
0
Altmetric
Original Article

Preparation and evaluation of a novel gastric mucoadhesive sustained-release acyclovir microsphere

, , , &
Pages 1098-1105 | Received 04 Dec 2009, Accepted 03 Feb 2010, Published online: 05 Nov 2010

References

  • Massimiliano G, Patrizia C, Maurizio R, Philip SB, Alan GEW, Mark ES, . (2007). Evaluation of a basic physiologically based pharmacokinetic model for simulating the first-time-in-animal study. Eur J Pharm Sci, 31:190–201.
  • Suresh K, Ritesh J, Deep K, Sudharshan H, Ashim KM. (2008). Pharmacokinetics of amino acid ester prodrugs of acyclovir after oral administration: Interaction with the transporters on Caco-2 cells. Int J Pharm, 362:93–101.
  • Tory P, Johnson RF, Melissa M, Timothy PB, Barry JM. (2007). Development of an aciclovir implant for the effective long-term control of herpes simplex virus type-1 infection in Vero cells and in experimentally infected SKH-1 mice. Int J Antimicro Ag, 30:428–35.
  • Fletcher C, Bean B. (1985). Evaluation of oral acyclovir therapy. Drug Intell Clin Pharm, 19:518–24.
  • Zeljka P, Natasa SB, Jelena FG, Anita M, Ivan J. (2005). Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir. J Control Release, 106:34–43.
  • Conti B, Bucolo C, Giannavola C, Puglisic G, Giunchedia P, Contea U. (1997). Biodegradable microspheres for the intravitreal administration of acyclovir: in vitro/in vivo evaluation. Eur J Pharm Sci, 5:287–293.
  • Lawa SL, Huang KJ, Chiang CH. (2000). Acyclovir-containing liposomes for potential ocular delivery corneal penetration and absorption. J Control Release, 63:135–40.
  • Alsarra IA, Hamed AY, Mahrous GM, Maghraby GMEI, Al-Robayan AA, Alanazi FK. (2009). Mucoadhesive polymeric hydrogels for nasal delivery of acyclovir. Drug Dev Ind Pharm, 35:352–62.
  • Rao CGG, Motiwale AV, Satyanarayana D, Subrahmanyam EVS. (2004). Formulation of taste masked oral microsphere of quinine sulphate by complexation. Indian J Pharm Sci, 66: 329–31.
  • Atyabi F, Sharma HL, Mohammad HAH, Fell JT. (1996). Controlled drug release from floating ion exchange resin beads. J Control Release, 42:25–8.
  • Hideki I, Kazuhiro F, Moji CA, Yoshinobu F. (2001) Use of ion-exchange resins to prepare 100 µm-sized microspheres with prolonged drug-release by the Wurster process. Int J Pharm, 216:67–76.
  • Plaizier-Vercammen JA. (1992). Investigation of the bioavailability of codeine from a cation ion-exchange sulfonic acid 1. Effect of parameters. Int J Pharm, 85:45–50.
  • Liu HF, Su XY,Li X, Zhao X, Zang L, Pan WS. (2006). Development of prolonged release microspheres of metformin hydrochloride using ion exchange resins. J Chin Pharm Sci, 15:155–61.
  • Ceschel GC, Bergamante V, Calabrese V, Biserni S, Ronchi C, Fini A. (2006). Design and evaluation of controlled release mucoadhesive tablets containing chlorhexidine in vitro. Drug Dev Ind Pharm, 32:53–61.
  • Lu GW, Jun HW. (1998). Diffusion studies of methotrexate in Carbopol and Poloxamer gels. Int J Pharm, 160:1–9.
  • Zhang XN, Chen J, Zhang Q. (2003). Study on the release of albendazole nanoparticles in vitro and its correlation with uptake in stomach and intestinal absorption kinetics in rats. Chin Pharm J, 38:932–5.
  • Michel C, Aprahamian M, Defontaine L, Couvreur P, Damgé C. (1991). The effect of site of administration in the gastrointestinal tract on the absorption of insulin from nanocapsules in diabetic rats. J Pharm Pharmacol, 43:1–5.
  • Akkaramongkolporn P, Ngawhirunpat T. (2003). Dual ambroxol and chlorpheniramine resinates as an alternative carrier in concurrent resinate administration. Phamazie, 58:195–9.
  • Perumal D. (2001). Microencapsulation of ibuprofen and Eudragit®RS 100 by the emulsion solvent diffusion technique. Int J Pharm, 218:1–11.
  • Fu J, Sun X, Zhang ZR. (2002). The investigation of bioadhesive property of Carbomer 934 by Gamma Camera in vivo. J Biomed Eng, 19:423–5.
  • Jankowski A, Jankowska AL, Lamparczyk H. (1998). Determination and pharmacokinetics of acyclovir after ingestion of microsphere form. J Pharm Biomed Anal, 18:249–54.
  • Grazia S, Md EA, Daniella W. (2004). Pharmacokinetics of acyclovir in rabbit skin after IV-bolus, ointment, and iontophoretic administrations. Int J Pharm, 274:201–11.
  • Wagner JG, Nelson E. (1964). Kinetic analysis of blood levels and urinary excretion in the absorptive phase after single dose of drug. J Pharm Sci, 53:1292–1243.
  • Liu HF, Zang L, Sun XY, Zhang S, Pan WS. (2005). Study on the basic physicochemical properties of the new excipient-sodium polystyrene sulfonate. Chin J New Drug, 14:1007–9.
  • Akiyama Y, Nagahara N, Kashihara T, Hirai S, Toguchi H. (1995). In vitro and in vivo evaluation of mucoadhesive microspheres prepared for the gastrointestinal tract using polyglycerol esters of fatty acids and a poly(acrylic acid) derivative. Pharm Res, 12:397–405.
  • Yao HM, Xu L, Han F, Che X, Dong Y, Wei M, . (2008). A novel riboflavin gastro-mucoadhesive delivery system based on ion-exchange fiber. Int J Pharm, 364:21–6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.