A pH-sensitive nanocomposite microsphere based on chitosan and montmorillonite with in vitro reduction of the burst release effect

References

• Muzzarelli R, Baldassarre V, Conti F, Ferrara P, Biagini G, Gazzanelli G, . (1988). Biological activity of chitosan ultrastructural study. Biomaterials, 9(3):247–52.
   PubMed Web of Science ®Google Scholar
• Cao J, Sun J, Wang X, Li X, Deng Y. (2009). N-Trimethyl chitosan-coated multivesicular liposomes for oxymatrine oral delivery. Drug Dev Ind Pharm, 35(11):1339–47.
   PubMed Web of Science ®Google Scholar
• Depan D, Kumar AP, Singh RP. (2009). Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite. Acta Biomater, 5:93–100.
   PubMed Web of Science ®Google Scholar
• Lee MK, Chun SK, Choi WJ, Kim JK, Choi SH, Kim A, . (2005). The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer. Biomaterials, 26(14): 2147–56.
   PubMed Web of Science ®Google Scholar
• Jain AK, Chalasani KB, Khar RK, Ahmed FJ, Diwan PV. (2007). Muco-adhesive multivesicular liposomes as an effective carrier for transmucosal insulin delivery. J Drug Target, 15(6): 417–27.
   PubMed Web of Science ®Google Scholar
• Malaekeh-Nikouei B, Tabassi SAS, Jaafari MR. (2008). Preparation, characterization, and mucoadhesive properties of chitosan-coated microspheres encapsulated with cyclosporine A. Drug Dev Ind Pharm, 34(5):492–8.
   PubMed Web of Science ®Google Scholar
• Zhou XF, Zhang XH, Yu XH, Kong W, Shen JC. (2008). The effect of conjugation to gold nanoparticles on the ability of low molecular weight chitosan to transfer DNA vaccine. Biomaterials, 29(1):111–7.
   PubMed Web of Science ®Google Scholar
• Ubaidulla U, Khar RK, Ahmed FJ, Panda AK. (2007). Development and in-vivo evaluation of insulin-loaded chitosan phthalate microspheres for oral delivery. J Pharm Pharmacol, 59(10):1345–51.
   PubMed Web of Science ®Google Scholar
• Akbuga J, Bergisadi N. (1996). 5-fluorouracil-loaded chitosan microspheres: Preparation and release characteristics. J Microencapsul, 13(2):161–68.
   PubMed Web of Science ®Google Scholar
• Kawaguchi H. (2000). Functional polymer microspheres. Prog Polym Sci, 25(8):1171–210.
   Web of Science ®Google Scholar
• Kumbar SG, Aminabhavi TM. (2003). Synthesis and Characterization of modified chitosan microspheres: Effect of the grafting ratio on the controlled release of nifedipine through microspheres. J Appl Polym Sci, 89:2940–9.
   Web of Science ®Google Scholar
• Quan JS, Jiang HL, Kim EM, Jeong HJ, Choi YJ, Guo DD, . (2008). pH-sensitive and mucoadhesive thiolated Eudragit-coated chitosan microspheres. Int J Pharm, 359(1–2):205–10.
   PubMed Web of Science ®Google Scholar
• Paul DR, Robeson LM. (2008). Polymer nanotechnology: Nanocomposites. Polymer, 49(15):3187–204.
   Web of Science ®Google Scholar
• Wang XY, Du YM, Yang JH, Tang YF, Luo JW. (2008). Preparation, characterization, and antimicrobial activity of quaternized chitosan/organic montmorillonite nanocomposites. J Biomed Mater Res A, 84A(2):384–90.
   Web of Science ®Google Scholar
• Aguzzi C, Cerezo P, Viseras C, Caramella C. (2007). Use of clays as drug delivery systems: Possibilities and limitations. Appl Clay Sci, 36(1–3):22–36.
   Web of Science ®Google Scholar
• Feje’r I, Kate M. (2001). Release of cationic drugs from loaded clay minerals. Colloid Polym Sci, 279:1177–82.
   Web of Science ®Google Scholar
• Park JK, Bin Choy Y, Oh JM, Kim JY, Hwang SJ, Choy JH. (2008). Controlled release of donepezil intercalated in smectite clays. Int J Pharm, 359(1–2):198–204.
   PubMed Web of Science ®Google Scholar
• Zheng JP, Luan L, Wang HY, Xi LF, Yao KD. (2007). Study on ibuprofen/montmorillonite intercalation composites as drug release system. Appl Clay Sci, 36:297–301.
   Web of Science ®Google Scholar
• Nunes CD, Vaz PD, Fernandes AC, Ferreira P, Romao CC, Calhorda MJ. (2007). Loading and delivery of sertraline using inorganic micro and mesoporous materials. Eur J Pharm Biopharm, 66(3):357–65.
   PubMed Web of Science ®Google Scholar
• Peng XH, Zhang L. (2005). Surface fabrication of hollow microspheres from N-methylated chitosan cross-linked with glutaraldehyde. Langmuir, 21(3):1091–5.
   PubMed Web of Science ®Google Scholar
• Lin FH, Lee YH, Jian CH, Wong JM, Shieh MJ, Wang, CY. (2002). A study of purified montmorillonite intercalated with 5-fluorouracil as drug carrier. Biomaterials, 23(9):1981–7.
   PubMed Web of Science ®Google Scholar
• Illum L. (1998). Chitosan and its use as a pharmaceutical excipient. Pharm Res, 15(9):1326–31.
   PubMed Web of Science ®Google Scholar
• Kumbar SG, Kulkarni AR, Aminabhavi TM. (2002). Crosslinked chitosan microspheres for encapsulation of diclofenac sodium: effect of crosslinking agent. J Microencapsul, 19(2):173–80.
   PubMed Web of Science ®Google Scholar
• Günister E, Pestreli D, ünlu CH, Atici O, Güngör N. (2007). Synthesis and characterization of chitosan-MMT biocomposite systems. Carbohydr Polym, 67:358–65.
   Web of Science ®Google Scholar
• Cui Y, Zhang Y, Tang X. (2008). In vitro and in vivo evaluation of ofloxacin sustained release pellets. Int J Pharm, 360(1–2):47–52.
   PubMed Web of Science ®Google Scholar
• Gibaldi M, Feldman S. (1967). Establishment of sink conditions in dissolution rate determinations-theoretical considerations and application to nondisintegrating dosage forms. J Pharm Sci, 56(10):1238–42.
   PubMed Web of Science ®Google Scholar
• Wagner JG. (1969). Interpretation of percent dissolved-time plots derived from in vitro testing of conventional tablets and capsules. J Pharm Sci, 58(10):1253–7.
   PubMed Web of Science ®Google Scholar
• Higuchi T. (1963). Mechanism of Sustained-action medication—Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci, 52(12):1145–9.
   PubMed Web of Science ®Google Scholar
• Reza MS, Quadir MA, Haider SS. (2003). Comparative evaluation of plastic, hydrophobic and hydrophilic polymers as matrices for controlled-release drug delivery. J Pharm Pharmaceut Sci, 6(2):282–91.
   PubMed Web of Science ®Google Scholar
• Agnihotri SA, Aminabhavi TM. (2004). Controlled release of clozapine through chitosan microparticles prepared by a novel method. J Control Release, 96(2):245–59.
   PubMed Web of Science ®Google Scholar