345
Views
35
CrossRef citations to date
0
Altmetric
Research Article

Enzymatic degradation of thiolated chitosan

, , , , &
Pages 1531-1539 | Received 13 Feb 2012, Accepted 06 Aug 2012, Published online: 12 Oct 2012

References

  • Millotti G, Samberger C, Fröhlich E, Bernkop-Schnürch A. (2009). Chitosan-graft-6-mercaptonicotinic acid: synthesis, characterization, and biocompatibility. Biomacromolecules, 10:3023–3027.
  • Vårum KM, Holme HK, Izume M, Stokke BT, Smidsrød O. (1996). Determination of enzymatic hydrolysis specificity of partially N-acetylated chitosans. Biochim Biophys Acta, 1291:5–15.
  • Kast CE, Bernkop-Schnürch A. (2001). Thiolated polymers–thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials, 22:2345–2352.
  • Bravo-Osuna I, Teutonico D, Arpicco S, Vauthier C, Ponchel G. (2007). Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface. Int J Pharm, 340:173–181.
  • Wakerly Z et al. (1996). In vitro evaluation of pectin-based colonic drug delivery systems. Int J Pharm 129: 73–77.
  • Kafedjiiski K, Föger F, Hoyer H, Bernkop-Schnürch A, Werle M. (2007). Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers. Drug Dev Ind Pharm, 33:199–208.
  • Schmitz T, Grabovac V, Palmberger TF, Hoffer MH, Bernkop-Schnürch A. (2008). Synthesis and characterization of a chitosan-N-acetyl cysteine conjugate. Int J Pharm, 347:79–85.
  • El-Sayed El-SA, Ezzat SM, Ghaly MF, Mansour M, E1-Bohey MA. (2006). Purification and characterization of two chitinases from Streptomyces albovinaceus S-22. World J Microbiol Biotechnol 16: 87–89.
  • Shin-ya Y, Lee M, Hinode H, Kajiuchi T. (2001). Effects of N-acetylation degree on N-acetylated chitosan hydrolysis with commercially available and modified pectinases. Biochem Eng J, 7:85–88.
  • Gaertner HF, Puigserver AJ. (1992). Increased activity and stability of poly(ethylene glycol)-modified trypsin. Enzyme Microb Technol, 14:150–155.
  • lke M, Ko Y, Yokohama K, Sumitani JI, Kawaguchi T, Ogasawara W, Okada H, Morikawa Y.. (2007). Cellobiohydrolase I (Ce17a) from Trichoderma reesei has chitosanase activity. J Mol Catal B-Enzymatic 47: 159–163.
  • Pantaleone D, Yalpani M, Scollar M. (1992). Unusual susceptibility of chitosan to enzymatic-hydrolysis. Carbohydrate Res 237: 325–332.
  • Muzzarelli RAA, Xia W, Tomasetti M, Ilari P. (1995). Depolymerization of chitosan and substituted chitosans with the aid of a wheat-germ lipase preparation. Enzyme Microbial Technol 17: 541–545.
  • Yalpani M, Pantaleone D. (1994). An examination of the unusual susceptibilities of aminoglycans to enzymatic-hydrolysis. Carbohydrate Res 256: 159–175.
  • Vetter A, Perera G, Leithner K, Klima G, Bernkop-Schnürch A. (2010). Development and in vivo bioavailability study of an oral fondaparinux delivery system. Eur J Pharm Sci, 41:489–497.
  • Ferrari F, Rossi S, Bonferoni MC, Caramella C, Karlsen J. (1997). Characterization of rheological and mucoadhesive properties of three grades of chitosan hydrochloride. Farmaco, 52:493–497.
  • Lee KY, Ha WS, Park WH. (1995). Blood compatibility and biodegradability of partially N-acylated chitosan derivatives. Biomaterials, 16:1211–1216.
  • Bernkop-Schnürch A, Hornof M, Zoidl T. (2003). Thiolated polymers–thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates. Int J Pharm, 260:229–237.
  • Kafedjiiski K, Hoffer M, Werle M, Bernkop-Schnürch A. (2006). Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate. Biomaterials, 27:127–135.
  • Gurbhele-Tupkar MC, Perez LR, Silva Y, Lees WJ. (2008). Rate enhancement of the oxidative folding of lysozyme by the use of aromatic thiol containing redox buffers. Bioorg Med Chem, 16:2579–2590.
  • Martien R, Loretz B, Thaler M, Majzoob S, Bernkop-Schnürch A. (2007). Chitosan-thioglycolic acid conjugate: an alternative carrier for oral nonviral gene delivery? J Biomed Mater Res A, 82:1–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.