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Research Article

Solid self-microemulsifying drug delivery system of ritonavir

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Pages 477-487 | Received 28 Sep 2012, Accepted 17 Jan 2013, Published online: 07 Mar 2013

References

  • Norvir® soft gelatin capsule, prescribing information. Available from: www.rxabbott.com/pdf/norpi2a.pdf [last accessed 2 August 2012].
  • Robert KZ, Richard AP. Pharmacological and therapeutic properties of ritonavir-boosted protease inhibitor therapy in HIV-infected patients. J Antimicro Chemo 2004;53:4–9
  • George H. Bioequivalence of pilot tablet formulations of ritonavir (RTV) to the marketed soft gel capsule (SGC) at a dose of 100 mg. 14th CROI Conference on Retroviruses and Opportunistic Infections; 25–28 Feb 2007; Los Angeles, CA. Available from: http://www.natap.org/2007/CROI/croi_54.htm [last accessed 10 August 2012].
  • Shilpi S, Mushir A, Sanjula B, et al. Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir. AAPS PharmSciTech 2010;11:518–27
  • Pranjali BG, Sanjay JK, Mangesh RB, Ashwini RM. Preparation and characterization of amorphous nanoparticles for solubility enhancement of ritonavir. Int J Pharm Inven 2012;2:27–35
  • Venkata DR, Chowdhary KPR. Formulation development of ritonavir tablets employing B cyclodextrin, solutol HS-15 and PVP-K30. Int J Pharm Res Dev 2012;4:45–50
  • Lawrence MJ, Rees GD. Microemulsions-based media as novel drug delivery systems. Adv Drug Deliv Rev 2000;45:89–121
  • Pouton CW. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and “self-microemulsifying” drug delivery systems. Eur J Pharm Sci 2000;11:93–8
  • Grove M, Műllertz A, Nielsen JL, Pedersen GP. Bioavailability of seocalcitol II: development and characterization of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. Eur J Pharm Sci 2006;28:233–42
  • Khang BK, Lee JS, Chon SK, et al. Development of self-microemulsifying drug delivery systems for oral bioavailability enhancement of simvastatin in beagle dogs. Int J Pharm 2004;274:65–73
  • Gursoy RN, Benita S. Self-emulsifying drug delivery systems for improved oral delivery of lipophilic drugs. Biomed Pharmacother 2004;58:173–82
  • Shyam V, Shruthi S, Cheng SC. Formulation and in vitro evaluation of self-emulsifying formulations of Cinnarizine. Drug Dev Ind Pharm 2011;38:1188–94
  • Myung JK, Hyung SK, Ho SJ, et al. In situ intestinal permeability and in vivo absorption characteristics of olmesartan medoxomil in self-microemulsifying drug delivery system. Drug Dev Ind Pharm 2012;38:587–96
  • Myung JK, Soo YJ, Woo HS, et al. Immediate release of ibuprofen from Fujicalin®-based fast-dissolving self-emulsifying tablets. Drug Dev Ind Pharm 2011;37:1298–305
  • Zhi QC, Ying L, Ji HZ, et al. Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system. Int J Nanomed 2012;7:1115–25
  • Yongjun W, Jin S, Tianhong Z, et al. Enhanced oral bioavailability of tacrolimus in rats by self-microemulsifying drug delivery systems. Drug Dev Ind Pharm 2011;37:1225–30
  • Oh DH, Kang JH, Kim DW, et al. Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier. Int J Pharm 2011;28:420, 412–18
  • Paola M, Maurizio V, Marzia C, Natascia M. New solid self-microemulsifying systems to enhance dissolution rate of poorly water soluble drugs. Pharm Dev Tech 2012;17:277–84
  • Dong WK, Jun HK, Dong HO, et al. Development of novel flurbiprofen-loaded solid self-microemulsifying drug delivery system using gelatin as solid carrier. J Microencapsul 2012;29:323–30
  • Jun HK, Dong HO, Yu-K O, et al. Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS). Eur J Pharm Biopharm 2012;80:289–97
  • Venkata RK, Suresh B, Raju J, Prabhakar RV. Oral self emulsifying powder of lercanidipine hydrochloride: formulation and evaluation. Powder Tech 2012;221:375–82
  • Srinivasan S, Rengarajan B, Prabagar B, et al. Solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidylcholine for enhanced bioavailability of highly lipophilic bioactive carotenoid lutein. Eur J Pharm Biopharm 2011;79:250–7
  • Saipin S, Sirima M, Narubodee P, et al. Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats. Eur J Pharm Biopharm 2010;76:475–85
  • Ping L, Anasuya G, Robert FW, et al. Effect of combined use of non-ionic surfactant on formation of oil-in-water microemulsions. Int J Pharm 2005;88:27–34
  • Ritonavir Capsules Authorized USP Non-US Monograph. Available from:   http://www.usp.org/sites/default/files/usp_pdf/EN/nonUSStandards/m4796.pdf [last accessed 11 August 2012].
  • Patel D, Sawant KK. Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS). Drug Dev Ind Pharm 2007;33:1318–26
  • Adhvait RD, Sadhana JR, Samir GP. Preparation and bioavailability assessment of SMEDDS containing valsartan. AAPS PharmSciTech 2010;11:314–21
  • You ML, Jui YW, Ying CC, et al. In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate. Int J Nanomed 2011;6:2445–57
  • Camilla S, Per H. Porous magnesium aluminometasilicate tablets as carrier of a cyclosporine self-emulsifying formulation. AAPS PharmSciTech 2009;10:1388–95
  • Law D, Schmitt EA, Marsh KC, et al. Ritonavir–PEG 8000 amorphous solid dispersions: in vitro and in vivo evaluations. J Pharm Sci 2004;93:563–70

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