269
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Influence of filler selection on twin screw foam granulation

, , &
Pages 35-42 | Received 14 May 2013, Accepted 09 Sep 2013, Published online: 10 Oct 2013

References

  • Djuric D, Kleinebudde P. Impact of screw elements on continuous granulation with a twin-screw extruder. J Pharm Sci 2008;97:4934–42
  • Keleb EI, Vermeire A, Vervaet C, Remon JP. Cold extrusion as a continuous single-step granulation and tabletting process. Eur J Pharm Biopharm 2001;52:359–68
  • Kleinebudde P, Lindner H. Experiments with an instrumented twin-screw extruder using a single-step granulation extrusion process. Int J Pharm 1993;94:49–58
  • Shah U. Use of a modified twin-screw extruder to develop a high-strength tablet dosage form. Pharm Technol 2005;29:52–66
  • Thompson MR, Sun J. Wet granulation in a twin-screw extruder: implications of screw design. J Pharm Sci 2010;99:2090–103
  • Dhenge RM, Washino K, Cartwright JJ, et al. Twin screw granulation using conveying screws: Effects of viscosity of granulation liquids and flow of powders. Powder Technol 2012;238:77–90
  • Keary CM, Sheskey PJ. Preliminary report of the discovery of a new pharmaceutical granulation process using foamed aqueous binders. Drug Dev Ind Pharm 2004;30:831–45
  • Thompson MR, Weatherley S, Pukadyil RN, Sheskey PJ. Foam granulation: new developments in pharmaceutical solid oral dosage forms using twin screw extrusion machinery. Drug Dev Ind Pharm 2012;38:771–84
  • Thompson MR, Mu B, Sheskey PJ. Aspects of foam stability influencing foam granulation in a twin screw extruder. Powder Technol 2012;228:339–48
  • Tan MXL, Hapgood KP. Foam granulation: Liquid penetration or mechanical dispersion? Chem Eng Sci 2011;66:5204–11
  • Tan MXL, Hapgood KP. Foam granulation: binder dispersion and nucleation in mixer-granulators. Chem Eng Res Des 2011;89:526–36
  • El Hagrasy AS, Hennenkamp JR, Burke MD, et al. Twin screw wet granulation: influence of formulation parameters on granule properties and growth behavior. Powder Technol 2013;238:108–15
  • Tan MXL, Wong LS, Lum KH, Hapgood KP. Foam and drop penetration kinetics into loosely packed powder beds. Chem Eng Sci 2009;64:2826–36
  • Kristensen J, Schæfer T, Kleinebudde P. Direct pelletization in a rotary processor controlled by torque measurements. II: effects of changes in the content of microcrystalline cellulose. AAPS Pharm Sci 2000;2:45–52
  • Iveson SM, Beathe JA, Page NW. The dynamic strength of partially saturated powder compacts: the effect of liquid properties. Powder Technol 2002;127:149–61
  • Iveson SM, Litster JD. Fundamental studies of granule consolidation part 2: quantifying the effects of particle and binder properties. Powder Technol 1998;99:243–50
  • Tan MXL, Nguyen TH, Hapgood KP. Drug distribution in wet granulation: foam versus spray. Drug Dev Ind Pharm 2013;39:1389–400
  • von Orelli JC. Search for technological reasons to develop a capsule or a tablet formulation. Basel, Switzerland: Universität Basel; 2005
  • Miwa A, Yajima T, Itai S. Prediction of suitable amount of water addition for wet granulation. Int J Pharm 2000;195:81–92
  • Iveson SM, Litster JD, Hapgood K, Ennis BJ. Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review. Powder Technol 2001;117:3–39
  • Chowdiah P, Misra BR, Kilbane JJ, et al. Foam propagation through soils for enhanced in-situ remediation. J Hazard Mater 1998;62:265–80
  • Hapgood KP, Litster JD, Biggs SR, Howes T. Drop penetration into porous powder beds. J Colloid Interface Sci 2002;253:353–66
  • Chitu TM, Oulahna D, Hemati M. Rheology, granule growth and granule strength: application to the wet granulation of lactose–MCC mixtures. Powder Technol 2011;208:441–53

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.