174
Views
9
CrossRef citations to date
0
Altmetric
Research Articles

Does P-glycoprotein contribute to amphotericin B epithelial transport in Caco-2 cells?

&
Pages 1130-1136 | Received 01 Apr 2014, Accepted 02 Jun 2014, Published online: 25 Jun 2014

References

  • Hamilton-Miller JM. Chemistry and biology of the polyene macrolide antibiotics. Bacteriol Rev 1973;37:166–96
  • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993;62:385–427
  • Ishizaki J, Ito S, Jin M, et al. Mechanism of decrease of oral bioavailability of cyclosporin A during immunotherapy upon coadministration of amphotericin B. Biopharm Drug Dispos 2008;29:195–203
  • Shao K, Wu J, Chen Z, et al. A brain-vectored angiopep-2 based polymeric micelles for the treatment of intracranial fungal infection. Biomaterials 2012;3:6898–907
  • Risovic V, Boyd M, Choo E, Wasan KM. Effects of lipid-based oral formulations on plasma and tissue amphotericin B concentrations and renal toxicity in male rats. Antimicrob Agents Chemother 2003;47:3339–42
  • Lee SD, Osei-Twum J-A, Wasan KM. Dose-dependent targeted suppression of P-glycoprotein expression and function in Caco-2 cells. Mol Pharm 2013;10:2323–30
  • Gershkovich P, Wasan EK, Lin M, et al. Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation. J Antimicrob Chemother 2009;64:101–8
  • Iida N, Takara K, Ohmoto N, et al. Reversal effects of antifungal drugs on multidrug resistance in MDR1-overexpressing HeLa cells. Biol Pharm Bull 2001;24:1032–36
  • Sakaeda T, Iwaki K, Kakumoto M, et al. Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs. J Pharm Pharmacol 2005;57:759–64
  • Möllgård L, Hellberg E, Smolowicz A, et al. Interactions between P-glycoprotein and drugs used in the supportive care of acute myeloid leukemia patients. Leuk Lymphoma 2001;42:177–85
  • Dantzig AH, Shepard RL, Cao J, et al. Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979. Cancer Res 1996;56:4171–9
  • Polli JW, Wring SA, Humphreys JE, et al. Rational use of in vitro P-glycoprotein assays in drug discovery. J Pharmacol Exp Ther 2001;299:620–8
  • Szakács G, Váradi A, Özvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox). Drug Discovery Today 2008;13:379–93
  • Ménez C, Buyse M, Besnard M, et al. Interaction between Miltefosine and Amphotericin B: consequences for their activities towards intestinal epithelial cells and Leishmania Donovani Promastigotes in vitro. Antimicrob Agents Chemother 2006;50:3793–800
  • Medoff J, Medoff G, Goldstein MN, et al. Amphotericin B-induced sensitivity to actinomycin D in drug-resistant HeLa cells. Cancer Res 1975;35:2548–52
  • Valeriote F, Medoff G, Dieckman J. Potentiation of anticancer agent cytotoxicity against sensitive and resistant AKR leukemia by amphotericin B. Cancer Res 1979;39:2041–5
  • Krishan A, Sauerteig A, Gordon K. Effect of amphotericin B on Adriamycin transport in P388 cells. Cancer Res 1985;45:4097–102
  • Mbongo N, Loiseau PM, Billion MA, Robert-Gero M. Mechanism of amphotericin B resistance in Leishmania Donovani Promastigotes. Antimicrob Agents Chemother 1998;42:352–7
  • Purkait B, Kumar A, Nandi N, et al. Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovani. Antimicrob Agents Chemother 2012;56:1031–41
  • White TC. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob Agents Chemother 1997;41:1482–7
  • Bizerra FC, Nakamura CV, De Poersch C, et al. Characteristics of biofilm formation by Candida tropicalis and antifungal resistance. FEMS Yeast Res 2008;8:442–50
  • Eddouzi J, Parker JE, Vale-Silva LA, et al. Molecular mechanisms of drug resistance in clinical candida species isolated from Tunisian hospitals. Antimicrob Agents Chemother 2013;57:3182–93
  • Garrigues A, Garrigues A, Escargueil AE, et al. The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane. Proc Natl Acad Sci USA 2002;99:10347–52
  • Bacso Z, Nagy H, Goda K, et al. Raft and cytoskeleton associations of an ABC transporter: P-glycoprotein. Cytometry A 2004;61A:105–16
  • Field FJ, Born E, Chen H, et al. Esterification of plasma membrane cholesterol and triacylglycerol-rich lipoprotein secretion in Caco-2 cells: possible role of P-glycoprotein. J Lipid Res 1995;36:1533–43
  • Luker GD, Nilsson KR, Covey DF, Piwnica-Worms D. Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol. J Biol Chem 1999;274:6979–91

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.