Preparation and in-vivo evaluation of dimenhydrinate buccal mucoadhesive films with enhanced bioavailability

References

• Brunton L, Parker K, Blumenthal D, Buxton I. Goodman and Gilman’s Manually of Pharmacology and Therapeutics. New York: Mc Graw-Hill; 2008:406
   Google Scholar
• British Pharmacopoeia. UK: 2010:703
   Google Scholar
• Genç L, Bilaç H, Güler E. Studies on controlled release dimenhydrinate from matrix tablet formulations. Pharm Acta Helv 1999;74:43–9
   PubMedGoogle Scholar
• Sweetman SC. Martindale: the extra pharmacopeia. 34th edn. Suffolk: The Pharmaceutical Press; 2005:431
   Google Scholar
• Desai J, Alexander K, Riga A. Characterization of polymeric dispersions of dimenhydrinate in ethyl cellulose for controlled release. Int J Pharm 2006;308:115–23
   PubMed Web of Science ®Google Scholar
• Missaghi S, Fassihi R. Release characterization of dimenhydrinate from an eroding and swelling matrix: selection of appropriate dissolution apparatus. Int J Pharm 2005;293:35–42
   PubMed Web of Science ®Google Scholar
• Novak KM. Drug facts and comparisons. 59th edn. St. Louis (MS): Wolters Kluwer Health 2005:866
   Google Scholar
• Varshosaz J, Emami J, Hashemi S. Influence of different solid-dispersion techniques upon the release of dimenhydrinate from chewing-gum formulations. Sci Pharm 2002;70:391–406
   Google Scholar
• Belgamwar VS, Chauk DS, Mahajan HS, et al. Formulation and evaluation of in situ gelling system of dimenhydrinate for nasal administration. Pharm Dev Technol 2009;14:240–8
   PubMed Web of Science ®Google Scholar
• Preis M, Pein M, Breitkreutz J. Development of a taste-masked orodispersible film containing dimenhydrinate. Pharmaceutics 2012;4:551–62
   PubMedGoogle Scholar
• Gibaldi M, Harris D, Robinson JR. The number of drugs administered buccally is increasing. Clin Pharmacol 1985;3:49–56
   Google Scholar
• Harris D, Robinson JR. Drug delivery via the mucous membranes of the oral cavity. J Pharm Sci 1992;81:1–10
   PubMed Web of Science ®Google Scholar
• Wong CF, Yuen KH, Peh KK. Formulation and evaluation of controlled release Eudragit buccal patches. Int J Pharm 1999;178:11–22
   PubMed Web of Science ®Google Scholar
• Kumria R, Nair AB, Al-Dhubiab BE. Loratidine buccal films for allergic rhinitis: development and evaluation. Drug Dev Ind Pharm 2014;40:625–31
   PubMed Web of Science ®Google Scholar
• Meher JG, Tarai M, Yadav NP, et al. Development and characterization of cellulose-polymethacrylate mucoadhesive film for buccal delivery of carvedilol. Carbohydr Polym 2013;96:172–80
   PubMed Web of Science ®Google Scholar
• Park DM, Song YK, Jee JP, et al. Development of chitosan-based ondansetron buccal delivery system for the treatment of emesis. Drug Dev Ind Pharm 2012;38:1077–83
   PubMed Web of Science ®Google Scholar
• Muzib YI, Kumari KS. Mucoadhesive buccal films of glibenclamide: development and evaluation. Int J Pharm Investig 2011;1:42–7
   PubMedGoogle Scholar
• Gu JM, Robinson JR, Leung SH. Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships. Crit Rev Ther Drug Carrier Syst 1988;5:21–67
   PubMed Web of Science ®Google Scholar
• Adhikari SNR, Nayak BS, Nayak AK, Mohanty B. Formulation and evaluation of buccal patches for delivery of atenolol. AAPS PharmSciTech 2010;11:1038–44
   PubMed Web of Science ®Google Scholar
• Merkle HP, Wolany G. Buccal delivery of peptide drugs. J Control Release 1992;21:155–64
   Web of Science ®Google Scholar
• Mortazavi SA, Smart JD. An in-vitro method for assessing the duration of mucoadhesion. J Control Release 1994;31:207–12
   Web of Science ®Google Scholar
• Smart JD. An in-vitro assessment of some mucosa-adhesive dosage forms. J Control Release 1991;73:69–74
   Google Scholar
• Peh KK, Wong CF. Polymeric films as vehicle for buccal delivery: swelling, mechanical and bioadhesive properties. J Pharm Pharm Sci 1999;2:53–61
   PubMed Web of Science ®Google Scholar
• Eroglu H, Sargon MF, Oner L. Chitosan formulations for steroid delivery: effect of formulation variables on in-vitro characteristics. Drug Dev Ind Pharm 2007;33:265–71
   PubMed Web of Science ®Google Scholar
• Patel VM, Prajapati BG, Patel MM. Design and characterization of chitosan-containing mucoadhesive buccal patches of propranolol hydrochloride. Acta Pharm 2007;57:61–72
   PubMedGoogle Scholar
• Vamshi-Vishnu Y, Chandrasekhar K, Ramesh G, Madhusudan RY. Development of mucoadhesive patches for buccal administration of carvedilol. Curr Drug Deliv 2007;4:27–39
   PubMedGoogle Scholar
• Tirosh B, Baluom M, Nassar T, et al. The effect of Eudragit RL-100 on the mechanical and mucoadhesion properties of polycarbophil dosage forms. J Control Release 1997;45:57–64
   Web of Science ®Google Scholar
• Ritthidej GC, Phaechamud T, Koizumi T. Moist heat treatment on physicochemical change of chitosan salt films. Int J Pharm 2002;232:11–22
   PubMed Web of Science ®Google Scholar
• Kalapathy U, Proctor A, Shultz J. Production and properties of flexible sodium silicate films from rice hull ash silica. Bioresour Technol 2000;72:99–106
   Web of Science ®Google Scholar
• Avachat AAM, Gujar KN, Wagh KV. Development and evaluation of tamarind seed xyloglucan-based mucoadhesive buccal films of rizatriptan benzoate. Carbohydr Polym 2013;91:537–42
   PubMed Web of Science ®Google Scholar
• Korsmeyer RW, Gurny R, Doelker E, et al. Mechanisms of potassium chloride release from compressed, hydrophilic, polymeric matrices: effect of entrapped air. J Pharm Sci 1983;72:1189–91
   PubMed Web of Science ®Google Scholar
• Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspension. J Pharm Sci 1961;50:874–5
   PubMed Web of Science ®Google Scholar
• Peppas NA. Analysis of fickian and non-fickian drug release from polymers. Pharm Acta Helv 1985;60:110–11
   PubMedGoogle Scholar
• Shojaei AH. Buccal mucosa as a route for systemic drug delivery: a review. J Pharm Pharm Sci 1998;1:15–30
   PubMedGoogle Scholar
• Bardelmeijer HA, Beijnen JH, Brouwer KR, et al. Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein. Clin Cancer Res 2000;6:4416–21
   PubMed Web of Science ®Google Scholar
• Jaouen V, Brayner R, Lantiat D, et al. In situ growth of gold colloids within alginate films. Nanotechnology 2010;21:185605. doi: 10.1088/0957-4484/21/18/185605
   PubMed Web of Science ®Google Scholar
• Bektaş A, Cevher E, Güngör S, Özsoy Y. Design and evaluation of polysaccharide-based transdermal films for the controlled delivery of nifedipine. Chem Pharm Bull 2014;62:144–52
   PubMed Web of Science ®Google Scholar
• Nair AB, Kumria R, Harsha S, et al. In-vitro techniques to evaluate buccal films. J Control Release 2013;166:10–21
   PubMed Web of Science ®Google Scholar
• Nafee NA, Boraie NA, Ismail FA, Mortada LM. Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride. Acta Pharm 2003;53:199–212
   PubMedGoogle Scholar
• Singh S, Jain S, Muthu MS, et al. Preparation and evaluation of buccal bioadhesive films containing clotrimazole. AAPS PharmSciTech 2008;9:660–7
   PubMed Web of Science ®Google Scholar
• Perioli L, Ambrogi V, Rubini D, et al. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease. J Control Release 2004;95:521–33
   PubMed Web of Science ®Google Scholar
• Cevher E, Sensoy D, Zloh M, Mulazimoglu L. Preparation and characterisation of natamycin: gamma-cyclodextrin inclusion complex and its evaluation in vaginal mucoadhesive formulations. J Pharm Sci 2008;97:4319–35
   PubMed Web of Science ®Google Scholar
• Güngör S, Erdal MS, Özsoy Y. Plasticizers in transdermal drug delivery systems. In: Luqman M, ed. Recent advances in plasticizers. Rijeka: Intech; 2012:91–112
   Google Scholar
• Nesseem DI, Eid SF, El-Houseny SS. Development of novel transdermal self-adhesive films for tenoxicam, an anti-inflammatory drug. Life Sci 2011;89:430–8
   PubMed Web of Science ®Google Scholar
• Palem CR, Gannu R, Doodipala N, et al. Transmucosal delivery of domperidone from bilayered buccal patches: in vitro, ex vivo and in vivo characterization. Arch Pharm Res 2011;34:1701–10
   PubMed Web of Science ®Google Scholar
• Boateng J, Mani J, Kianfar F. Improving drug loading of mucosal solvent cast films using a combination of hydrophilic polymers with amoxicillin and paracetamol as model drugs. Biomed Res Int 2013; Article ID 198137, 8 pages. doi: 10.1155/2013/198137
   Google Scholar
• Kaur G, Singh D, Brar V. Bioadhesive okra polymer based buccal patches as platform for controlled drug delivery. Int J Biol Macromol 2014;70:408–19
   PubMed Web of Science ®Google Scholar
• Ghosh SK, Cherstvy AG, Metzler R. Deformation propagation in responsive polymer network films. The J Chem Phys 2014;141:074903. doi:101063/1.4893056
   Google Scholar
• Sezer AD, Hatipoğlu F, Cevher E, et al. Chitosan film containing fucoidan as a wound dressing for dermal burn healing: preparation and in vitro/in vivo evaluation. AAPS PharmSciTech 2007;8:Article 39
   Google Scholar
• Akash MSH, Khan IU, Shah SNH, et al. Sustained release hydrophilic matrices based on xanthan gum and hydroxypropyl methylcellulose: development, optimization, in-vitro and in-vivo evaluation. J App Pharm 2010;4:89–103
   Google Scholar
• Tas C, Özkan Y, Savaşer A, Baykara T. In-vitro release studies of chlorpheniramine maleate from gels prepared by different cellulose derivatives. Farmaco 2003;58:605–11
   PubMedGoogle Scholar
• Roy D, Rohera BD. Comparative evaluation of rate of hydration and matrix erosion of HEC and HPC and study of drug release from their matrices. Eur J Pharm Sci 2002;16:193–9
   PubMed Web of Science ®Google Scholar
• Jones D. Pharmaceutical applications of polymers for drug delivery. Rapra Rev Rep 2004;15:1–121
   Google Scholar
• Siddaramaiah RN. Feasibility of xanthan gum-sodium alginate as a transdermal drug delivery system for domperidone. J Mater Sci Mater Med 2009;20:2085–89
   PubMed Web of Science ®Google Scholar
• Sing M, Tiwary AK, Kaur G. Investigations on interpolymer complexes of cationic guar gum and xanthan gum for formulation of bioadhesive films. Res Pharm Sci 2010;5:79–87
   PubMedGoogle Scholar
• Law V, Knox C, Djoumbou Y, et al. DrugBank 4.0: shedding new light on drug metabolism. Acids Res 2014. [Epub ahead of print]. doi: 10.1093/nar/gkt1068.
   Web of Science ®Google Scholar
• Walters KM, Mason WD, Badr MZ. Effect of propylene glycol on the disposition of Dramamine in the rabbit. Drug Metab Dispos 1993;21:305–8
   PubMed Web of Science ®Google Scholar
• Wu X, Desai KGH, Mallery SR, et al. Mucoadhesive fenretinide patches for site-specific chemoprevention of oral cancer: enhancement of oral mucosal permeation of fenretinide by coincorporation of propylene glycol and menthol. Mol Pharm 2012;9:937–45
   PubMed Web of Science ®Google Scholar
• Hoogstraate AJ, Senel S, Cullander C, et al. Effects of bile salts on transport rates and routes of FITC-labelled compounds across porcine buccal epithelium in vitro. J Control Release 1996;40:211–21
   Web of Science ®Google Scholar
• Widmaier EP, Raff H, Strang KT. Vander’s human physiology: the mechanisms of body function’. New York: McGraw-Hill; 2011:704–5
   Google Scholar