Development and optimization of a new processing approach for manufacturing topical liposomes-in-hydrogel drug formulations by dual asymmetric centrifugation

References

• Hay RJ, Johns NE, Williams HC, et al. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions. J Invest Dermatol 2014;134:1527–34.
   PubMed Web of Science ®Google Scholar
• Delousie LA. Applications of nanotechnology in dermatology. J Invest Dermatol 2012;132:964–75.
   PubMed Web of Science ®Google Scholar
• Hurler J, Škalko-Basnet N. Advancements in burn therapy: promise of nanomedicine. In: McLaughlin ES, Paterson AO, eds. Burns: prevention, causes and treatment. New York: Nova Science Publishers; 2012:39–64.
   Google Scholar
• Vanic Ž, Holsæter AM, Škalko-Basnet N. (Phospho)lipid-based nanosystems for skin administration. Curr Pharm Des 2015;21: 4174–92.
   PubMed Web of Science ®Google Scholar
• Couvreur P, Vauthier C. Nanotechnology: intelligent design to treat complex disease. Pharm Res 2006;23:1417–50.
   PubMed Web of Science ®Google Scholar
• Mezei M, Gulasekharam V. Liposomes – a selective drug delivery system for the topical route of administration I. Lotion dosage form. Life Sci 1980;26:1473–7.
   PubMed Web of Science ®Google Scholar
• Hurler J, Žakelj S, Mravljak J, et al. The effect of lipid composition and liposome size on the release properties of liposomes-in-hydrogel. Int J Pharm 2013;456:49–57.
   PubMed Web of Science ®Google Scholar
• Mozafari MR. Liposomes: an overview of manufacturing techniques. Cell Mol Biol Lett 2005;10:711–19.
   PubMed Web of Science ®Google Scholar
• Massing U, Cicko S, Ziroli V. Dual asymmetric centrifugation (DAC) – a new technique for liposome preparation. J Control Release 2008;125:16–24.
   PubMed Web of Science ®Google Scholar
• Hirsch M, Ziroli V, Helm M, Massing U. Preparation of small amounts of sterile siRNA-liposomes with high entrapping efficiency by dual asymmetric centrifugation (DAC). J Control Release 2009;135:80–8.
   PubMed Web of Science ®Google Scholar
• Tian W, Schulze S, Brandl M, Winter G. Vesicular phospholipid gel-based depot formulations for pharmaceutical proteins: development and in vitro evaluation. J Control Release 2010; 142:319–25.
   PubMed Web of Science ®Google Scholar
• Adrian JE, Wolf A, Steinbach A, et al. Targeted delivery to neuroblastoma of novel siRNA-anti-GD2-liposomes prepared by dual asymmetric centrifugation and sterol-based post-insertion method. Pharmaceut Res 2011;28: 2261–72.
   PubMed Web of Science ®Google Scholar
• Helm F, Fricker G. Liposomal conjugates for drug delivery to the central nervous system. Pharmaceutics 2015;7:27–42.
   PubMedGoogle Scholar
• Elnaggar YSR, El-Refaie WM, El-Massik MA, Abdallah OY. Lecithin-based nanostructured gels for skin delivery: an update on state of art and recent applications. J Control Release 2014;180:10–24.
   PubMed Web of Science ®Google Scholar
• Brandl M. Vesicular phospholipid gels. In: Weissig V, ed. Liposomes – methods and protocols, Volume 1: pharmaceutical nanocarriers. 1st edn. New York: Humana Press; 2010:205–12.
   Google Scholar
• Elmoslemany R, Abdallah O, El-Khordagui L, Khalafallah N. Propylene glycol liposomes as a topical delivery system for miconazole nitrate: comparison with conventional liposomes. AAPS PharmSciTech 2012;13:723–31.
   PubMed Web of Science ®Google Scholar
• Zykova SN, Balandina KA, Vorokhobina NV, et al. Macrophage stimulating agent soluble yeast β-1,3/1,6-glucan as a topical treatment of diabetic foot and leg ulcers: a randomized, double blind, placebo-controlled phase II study. J Diabetes Investig 2014;5:392–9.
   PubMed Web of Science ®Google Scholar
• Heal CF, Buettner PG, Cruickshak R, et al. Does single application of topical chloramphenicol to high risk sutured wounds reduce incidence of wound infection after minor surgery? Prospective randomised placebo controlled double blind trial. BMJ 2009;338:a2812.
   PubMed Web of Science ®Google Scholar
• di Cagno M, Styskala J, Hlavac J, et al. Liposomal solubilization of new 3-hydroxy-quinolinone derivatives with promising anticancer activity: a screening method to identify maximum incorporation capacity. J Liposome Res 2011;21: 272–8.
   PubMed Web of Science ®Google Scholar
• Jøraholmen MW, Vanić Ž, Tho I, Škalko-Basnet N. Chitosan-coated liposomes for topical vaginal therapy: assuring localized drug effect. Int J Pharm 2014;472:94–101.
   PubMed Web of Science ®Google Scholar
• Bartlett GR. Phosphorus assay in column chromatography. J Biol Chem 1959;234:466–8.
   PubMed Web of Science ®Google Scholar
• Elsayed MMA, Abdallah OY, Naggar VF, Khalafallah NM. Lipid vesicles for skin delivery of drugs: reviewing three decades of research. Int J Pharm 2007;332:1–16.
   PubMed Web of Science ®Google Scholar
• Ferreira LS, Ramaldes GA, Nunan EA, Ferreira LAM. In vitro skin permeation and retention of paromomycin from liposomes for topical treatment of the cutaneous leishmaniasis. Drug Dev Ind Pharm 2004;30:289–96.
   PubMed Web of Science ®Google Scholar
• Chen G, Li D, Jin Y, et al. Deformable liposomes by reverse-phase evaporation method for an enhanced skin delivery of (+)-catechin. Drug Dev Ind Pharm 2013;40:260–5.
   PubMed Web of Science ®Google Scholar
• Wagner A, Vorauer-Uhl K, Katinger H. Liposomes produced in a pilot scale: production, purification and efficiency aspects. Eur J Pharm Biopharm 2002;54:213–19.
   PubMed Web of Science ®Google Scholar
• Huang Z, Li X, Zhang T, et al. Progress involving new techniques for liposome preparation. Asian J Pharma Sci 2014;9:176–82.
   Google Scholar
• Kikuchi H, Yamauchi H, Hirota S. A polyol dilution method for mass production of liposomes. J Liposome Res 1994; 4:71–91.
   Web of Science ®Google Scholar
• Pavelić Ž, Škalko-Basnet N, Jalsenjak I. Liposomes containing drugs for treatment of vaginal infections. Eur J Pharm Sci 1999; 8:345–51.
   PubMed Web of Science ®Google Scholar
• Pavelić Ž, Škalko-Basnet N, Filipović-Grčić J, et al. Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir. J Control Release 2005; 106:34–43.
   PubMed Web of Science ®Google Scholar
• Verma DD, Verma S, Blume G, Fahir A. Particle size of liposomes influences dermal delivery of substances into skin. Int J Pharm 2003;258:141–51.
   PubMed Web of Science ®Google Scholar
• Kirjavainen M, Urtti A, Valjakka-Koskela R, et al. Liposome-skin interactions and their effects on the skin permeation of drugs. Eur J Pharm Sci 1999;7:279–86.
   PubMed Web of Science ®Google Scholar
• du Plessis J, Ramachandran C, Weiner N, Müller DG. The influence of particle size of liposomes on the deposition of drug into skin. Int J Pharm 1994;103:277–82.
   Web of Science ®Google Scholar
• Engesland A, Skalko-Basnet N, Flaten GE. Phospholipid vesicle-based permeation assay and EpiSkin® in assessment of drug therapies destined for skin administration. J Pharm Sci 2015; 104:1119–27.
   PubMed Web of Science ®Google Scholar
• Pavelić Ž, Škalko-Basnet N, Jalsenjak I. Liposomal gel with chloramphenicol: characterisation and in vitro release. Acta Pharm 2004;54:319–30.
   PubMedGoogle Scholar
• Castangia I, Manca ML, Matricadi P, et al. Effect of diclofenac and glycol intercalation on structural assembly of phospholipid lamellar vesicles. Int Pharm 2013;456:1–9.
   PubMed Web of Science ®Google Scholar
• Manca ML, Castangia I, Matricardi P, et al. Molecular arrangements and interconnected bilayer formation induced by alcohol or polyalcohol in phospholipid vesicles. Colloids Surf B Biointerfaces 2014;117:360–7.
   PubMed Web of Science ®Google Scholar
• Palac Z, Hurler J, Škalko-Basnet N, et al. Elastic liposomes-in-vehicle formulations destined for skin therapy: the synergy between type of liposomes and vehicle. Drug Dev Ind Pharm 2014;41:1247–53.
   PubMed Web of Science ®Google Scholar
• Škalko N, Čajkovac M, Jalsenjak I. Liposomes with metronidazole for topical use: the choice of preparation method and vehicle. J Liposome Res 1998;8:283–93.
   Web of Science ®Google Scholar
• Hurler J, Berg OA, Skar M, et al. Improved burns therapy: liposomes-in-hydrogel delivery system for mupirocin. J Pharm Sci 2012;101:3906–15.
   PubMed Web of Science ®Google Scholar
• Boer Y, Pijnenburg A. HPLC determination of chloramphenicol degradation in eye drops. Pharm Weekbl Sci 1983;5:95–101.
   PubMedGoogle Scholar
• Lv FF, Zheng LQ, Tung CH. Phase behavior of the microemulsions and the stability of the chloramphenicol in the microemulsion-based ocular drug delivery system. Int J Pharm 2005;301:237–46.
   PubMed Web of Science ®Google Scholar