Formulation and development of ophthalmic in situ gel for the treatment ocular inflammation and infection using application of quality by design concept

References

• Nanjawade B, Manvi F, Manjappa A. In situ-forming hydrogels for sustained ophthalmic drug delivery. J Control Release 2007;122:119–34.
   PubMed Web of Science ®Google Scholar
• Araajo J, Gonzalez E, Egea M, et al. Nanomedicines for ocular NSAIDs: safety on drug delivery. Nanotechnol Biol Med 2009;5:394–401.
   PubMed Web of Science ®Google Scholar
• Liu Z, Li J, Nie S, et al. Study of an alginate/HPMC-based in situ gelling ophthalmic delivery system for gatifloxacin. Int J Pharm 2006;315:12–7.
   PubMed Web of Science ®Google Scholar
• Qi H, Chen W, Huang C, et al. Development of a poloxamer analogs/carbopol-based in situ gelling and mucoadhesive ophthalmic delivery system for puerarin. Int J Pharm 2007; 337:178–87.
   PubMed Web of Science ®Google Scholar
• Srividya B, Cardoza R, Amin P. Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system. J Control Release 2001;73:205–11.
   PubMed Web of Science ®Google Scholar
• Wu C, Qi H, Chen W, et al. . Preparation and evaluation of a carbopol/HPMC-based in situ gelling ophthalmic system for puerarin. Yakugaku Zasshi 2007;127:183–91.
   PubMed Web of Science ®Google Scholar
• Wei G, Xu H, Ding P, et al. Thermosetting gels with modulated gelation temperature for ophthalmic use: the rheological and gamma scintigraphic studies. J Control Release 2002;83:65–74.
   PubMed Web of Science ®Google Scholar
• (a) Dumortier G, Grossiord J, Agnely F, et al. A review of poloxamer 407 pharmaceutical and pharmacological characteristics. Pharm Res 2006;23:2709–28. (b) Ludwig A. The use of mucoadhesive polymers in ocular drug delivery. Adv Drug Deliver Rev 2005;23:2709–39.
   PubMed Web of Science ®Google Scholar
• Almeida H, Amaral MH, Lobao P, Lobo JM. In situ gelling systems: a strategy to improve the bioavailability of ophthalmic pharmaceutical formulations. Drug Discov Today 2014;19: 400–12.
   PubMed Web of Science ®Google Scholar
• Sattone M. Progress and problems in ophthalmic drug delivery. Business Briefing: Pharmatech 2002;1:167–71.
   Google Scholar
• Ma W, Xu H, Wang C, et al. Pluronic F127-g-polyacrylic acid copolymers as in situ gelling vehicle for ophthalmic drug delivery system. Int J Pharm 2008;350:247–56.
   PubMed Web of Science ®Google Scholar
• Klouda L, Mikos A. 2008. Thermoresponsive hydrogels in biomedical applications. Eur J Pharm Biopharm 2008;68:34–45.
   PubMed Web of Science ®Google Scholar
• RxList [The Internet Drug Index]. Tobradex: side effects center. Available from: http://www.rxlist.com/tobradex-side-effects-drug-center.htm [last accessed 22 Jun 2015].
   Google Scholar
• Nayak A, Pal D. Development of pH-sensitive tamarind seed polysaccharide - alginate composite beads for controlled diclofenac sodium delivery using response surface methodology. Int J Biol Macromol 2011;49:784–93.
   PubMed Web of Science ®Google Scholar
• Maltesen M, Bjerregaard S, Hovgaard L, et al. Quality by design - Spray drying of insulin intended for inhalation. Eur J Pharm Biopharm 2008;70:828–38.
   PubMed Web of Science ®Google Scholar
• Mennini N, Furlanetto S, Cirri Mura P. Quality by design approach for developing chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-β cyclodextrin-PVP complex. Eur J Pharm Biopharm 2012;80:67–75.
   PubMed Web of Science ®Google Scholar
• Bruni G, Berbenni V, Milanese C, et al. Drug-excipient compatibility studies in binary and ternary mixtures by physico-chemical techniques. J Therm Anal Calorim 2009; 102:193–01.
   Web of Science ®Google Scholar
• Aboelwa AA, Makhl A. In vivo evaluation and application of central composite design in the optimization of amisulpride self-emulsifying drug delivery system. Am J Drug Disc and Dev 2012;2:1–16.
   Google Scholar
• Nagarwal R, Srinatha A, Pandit J. In situ forming formulation: development, evaluation, and optimization using 3(3) factorial design. AAPS PharmSciTech 2009;10:977–84.
   PubMed Web of Science ®Google Scholar
• Gratieri T, Gelfuso G, Rocha E, et al. A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery. Eur J Pharm Biopharm 2010;75:186–93.
   PubMed Web of Science ®Google Scholar
• Asasutjarit R, Thanasanchokpibull S, Fuongfuchat A, Veeranondha S. Optimization and evaluation of thermoresponsive diclofenac sodium ophthalmic in situ gels. Int J Pharm 2011;411:128–35.
   PubMed Web of Science ®Google Scholar
• Varshosaz J, Tabbakhian M, Salmani Z. Designing of a thermosensitive chitosan/poloxamer in situ gel for ocular delivery of ciprofloxacin. Open Drug Deliv J 2008;2:61–70.
   Google Scholar
• Talei Franzesi G, Ni B, Ling Y, Khademhosseini A. A controlled-release strategy for the generation of cross-linked hydrogel microstructures. J Am Chem Soc 2006;128:15064–6.
   PubMed Web of Science ®Google Scholar
• El-Kamel A, El-Khatib M. Thermally reversible in situ gelling carbamazepine liquid suppository. Drug Delivery 2006;13: 143–8.
   PubMed Web of Science ®Google Scholar
• Kim B, Kim Y, Ok J. Development of liquid chromatographic method for the analysis of kanamycin residues in varicella vaccine using phenylisocyanate as a derivatization reagent. J Chromatogr B Biomed Sci Appl 2001;752:173–7.
   PubMed Web of Science ®Google Scholar
• Rodriguesa L, Leitea H. In vitro release and characterization of chitosan films as dexamethasone carrier. Int J Pharm 2009; 368:1–6.
   PubMed Web of Science ®Google Scholar
• Shantier SW, Gadkariem EA. A colorimetric method for the determination of tobramycin. Int J of Drug Form Res 2011;4: 260–72.
   Google Scholar
• Le Bourlais C, Acar L, Zia H, et al. Ophthalmic drug delivery systems-recent advances. Prog Retin Eye Res 1998;17:33–58.
   PubMed Web of Science ®Google Scholar
• Oechsner M, Keipert S. Polyacrylic acid/polyvinylpyrrolidone bipolymeric systems. I. Rheological and mucoadhesive properties of formulations potentially useful for the treatment of dry-eye-syndrome. Eur J Pharm Biopharm 1999;47:113–8.
   PubMed Web of Science ®Google Scholar
• Fang J, Yu S, Wu P, et al. In vitro skin permeation of estradiol from various proniosome formulations. Int J Pharm 2001;215: 91–9.
   PubMed Web of Science ®Google Scholar
• Mayol L, Quaglia F, Borzacchiello A, Ambrosio Lrotonda M. A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: rheological, mucoadhesive and in vitro release properties. Eur J Pharm Biopharm 2008;70:199–206.
   PubMed Web of Science ®Google Scholar
• Gupta H, Jain S, Mathur R, et al. . Sustained ocular drug delivery from a temperature and pH triggered novel in situ gel system. Drug Deliv 2007;14:507–15.
   PubMed Web of Science ®Google Scholar
• Zignani M, Tabatabay C, Gurny R. Topical semi-solid drug delivery, kinetics and tolerance of ophthalmic hydrogels. Adv Drug Deliver Rev 1995;16:51–60.
   Web of Science ®Google Scholar
• Dicolo G, Zambito Y, Zaino C, Sansa M. Selected polysaccharides at comparison for their mucoadhesiveness and effect on precorneal residence of different drugs in the rabbit model. Drug Dev Ind Pharm 2009;35:941–9.
   PubMed Web of Science ®Google Scholar
• Bozdag S, Dillen K, Vandervoort J, Ludwig A. The effect of freeze-drying with different cryoprotectants and gamma-irradiation sterilization on the characteristics of ciprofloxacin HCl-loaded poly D,L-lactide-glycolide nanoparticles. J Pharm Pharmacol 2005;57:699–708.
   PubMed Web of Science ®Google Scholar
• Fang JY, Chen JP. Characterization & Evaluation of Silk protein hydrogels for drug delivery. Chem Pharm Bull 2006;44:373–7.
   Google Scholar
• Wagenlehner F, Sorgel F. Pharmacokinetics of Ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose. Int J Antimicrob Agents 2006;27:7–14.
   PubMed Web of Science ®Google Scholar
• Russ H, McCleary D, Katimy R, et al. Development and validation of a stability-indicating HPLC method for the determination of tobramycin and its related substances in an ophthalmic suspension. J Liq Chrom Rel Technol 1998;21: 2165–81.
   Web of Science ®Google Scholar
• Baranowski P, Karolewicz B, Gajda M, Pluta J. Ophthalmic drug dosage forms, characterisation and research methods. Scientific World J 2014;20141–14.
   Web of Science ®Google Scholar
• Yu LX. Pharmaceutical quality by design: product and process development, understanding, and control. Pharm Res 2008;25:781–91.
   PubMed Web of Science ®Google Scholar
• Amelie B, Elias F, Jean LG, et al. Characterization of a new ocular delivery system based on a dispersion of liposomes in a thermosensitive gel. Int J Pharm 1998;162:119–27.
   Web of Science ®Google Scholar
• Terry J. Human tear osmotic pressure: diurnal variations and the closed eye. Arch Ophthalmol 1978;96:120–32.
   PubMedGoogle Scholar
• Ruel-Gariepy E, Leroux JC. In situ-forming hydrogels-review of temperature-sensitive systems. Eur J Pharm Biopharm 2004; 58:409–26.
   PubMed Web of Science ®Google Scholar
• Fialho S, Silva-Cunha A. New vehicle based on a microemulsion for topical ocular administration of dexamethasone. Clin Exp Ophthalmol 2004;32:626–32.
   PubMed Web of Science ®Google Scholar
• Patel N, Chotai N, Patel J, et al. Comparison of in vitro dissolution profiles of oxcarbazepine-HP β-CD tablet formulations with marketed oxcarbazepine tablets. Dissolut Technol 2008;15:28–34.
   Google Scholar
• Bozdag S, Gumus K, Gumus O, Unlu N. Formulation and in vitro evaluation of cysteamine hydrochloride viscous solutions for the treatment of corneal cystinosis. Eur J Pharm Biopharm 2008;70:260–9.
   PubMed Web of Science ®Google Scholar