391
Views
13
CrossRef citations to date
0
Altmetric
Research Articles

Physicochemical characterization of spray-dried PLGA/PEG microspheres, and preliminary assessment of biological response

&
Pages 1504-1514 | Received 04 Aug 2015, Accepted 25 Jan 2016, Published online: 02 Mar 2016

References

  • Shen J, Choi S, Qu W, et al. In vitro-in vivo correlation of parenteral risperidone polymeric microspheres. J Control Release 2015;218:2–12.
  • Tiberg F, Roberts J, Cervin C, et al. Octreotide s.c. depot provides sustained octreotide bioavailability and similar IGF-1 suppression to octreotide LAR in healthy volunteers. Br J Clin Pharmacol 2015;80:460–72.
  • Everest E, Tsilianidis LA, Raissouni N, et al. Postinjection muscle fibrosis from Lupron. Case Rep Pediatr 2015;2015:938264.
  • Braeckman J, Michielsen D. Efficacy and tolerability of 1- and 3-month leuprorelin acetate depot formulations (Eligard((R))/Depo-Eligard((R))) for advanced prostate cancer in daily practice: a Belgian prospective non-interventional study. Arch Med Sci 2014;10:477–83.
  • LaRue S, Malloy J. Evaluation of the dual-chamber pen design for the injection of exenatide once weekly for the treatment of type 2 diabetes. J Diabetes Sci Technol 2015;9:815–21.
  • Scheen AJ. [Bydureon: first once weekly GLP-1 receptor agonist (exenatide LAR)]. Rev Med Liege 2014;69:214–19.
  • Gokhale KS, Jonnalagadda S. Preparation and evaluation of sustained release infliximab microspheres. PDA J Pharm Sci Technol 2013;67:255–66.
  • Tabata Y, Ikada Y. Macrophage phagocytosis of biodegradable microspheres composed of L-lactic acid/glycolic acid homo- and copolymers. J Biomed Mater Res 1988;22:837–58.
  • Marberger M, Kaisary AV, Shore ND, et al. Effectiveness, pharmacokinetics, and safety of a new sustained-release leuprolide acetate 3.75-mg depot formulation for testosterone suppression in patients with prostate cancer: a Phase III, open-label, international multicenter study. Clin Ther 2010;32:744–57.
  • Segawa N, Nishida T, Hamada S, et al. Skin reaction induced by subcutaneous injection of LH-RH analogue. Hinyokika Kiyo 2007;53:695–8.
  • Immordino ML, Dosio F, Cattel L. Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. Int J Nanomedicine 2006;1:297–315.
  • Glavas L, Olsen P, Odelius K, Albertsson AC. Achieving micelle control through core crystallinity. Biomacromolecules 2013;14:4150–6.
  • Cheng G, Cai Z, Wang L. Biocompatibility and biodegradation of poly(hydroxybutyrate)/poly(ethylene glycol) blend films. J Mater Sci Mater Med 2003;14:1073–8.
  • Alcantar NA, Aydil ES, Israelachvili JN. Polyethylene glycol-coated biocompatible surfaces. J Biomed Mater Res 2000;51:343–51.
  • Zhang K, Tang X, Zhang J, et al. PEG-PLGA copolymers: their structure and structure-influenced drug delivery applications. J Control Release 2014;183:77–86.
  • Swaminathan V, Tchao R, Jonnalagadda S. Physical characterization of thin semi-porous poly(L-lactic acid)/poly(ethylene glycol) membranes for tissue engineering. J Biomater Sci Polym Ed 2007;18:1321–33.
  • Jonnalagadda S, Robinson DH. Effect of thickness and PEG addition on the hydrolytic degradation of PLLA. J Biomater Sci Polym Ed 2004;15:1317–26.
  • Jonnalagadda S, Robinson DH. Effect of the inclusion of PEG on the solid-state properties and drug release from polylactic acid films and microcapsules. J Appl Polym Sci 2004;93:2025–30.
  • Sollohub K, Cal K. Spray drying technique: II. Current applications in pharmaceutical technology. J Pharm Sci 2010;99:587–97.
  • Takada S, Uda Y, Toguchi H, Ogawa Y. Application of a spray drying technique in the production of TRH-containing injectable sustained-release microparticles of biodegradable polymers. PDA J Pharm Sci Technol 1995;49:180–4.
  • Arpagaus C, Schafroth N, Büchi Labortechnik A. Spray dried biodegradable polymers as target material for controlled drug delivery. Best@ Büchi; 2007.
  • Hamishehkar H, Emami J, Najafabadi AR, et al. Effect of carrier morphology and surface characteristics on the development of respirable PLGA microcapsules for sustained-release pulmonary delivery of insulin. Int J Pharm 2010;389:74–85.
  • Mok H, Park TG. Water-free microencapsulation of proteins within PLGA microparticles by spray drying using PEG-assisted protein solubilization technique in organic solvent. Eur J Pharm Biopharm 2008;70:137–44.
  • Triglia RP, Linscott WD. Titers of nine complement components, conglutinin and C3b-inactivator in adult and fetal bovine sera. Mol Immunol 1980;17:741–8.
  • Namekar M, Kumar M, O'Connell M, Nerurkar VR. Effect of serum heat-inactivation and dilution on detection of anti-WNV antibodies in mice by West Nile virus E-protein microsphere immunoassay. PLoS One 2012;7:e45851.
  • Bhattacharjee S, Rietjens IM, Singh MP, et al. Cytotoxicity of surface-functionalized silicon and germanium nanoparticles: the dominant role of surface charges. Nanoscale 2013;5:4870–83.
  • Aranda A, Sequedo L, Tolosa L, et al. Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cells. Toxicol In Vitro 2013;27:954–63.
  • Takanashi T, Ogura Y, Taguchi H, et al. Fluorophotometric quantitation of oxidative stress in the retina in vivo. Invest Ophthalmol Vis Sci 1997;38:2721–8.
  • Morîntale E, Harabor A, Constantinescu C, Rotaru P. Use of heat flows from DSC curve for calculation of specific heat of the solid materials. Physics AUC 2013;23:89–94.
  • Zhu Q, Taylor LS, Harris MT. Evaluation of the microstructure of semicrystalline solid dispersions. Mol Pharm 2010;7:1291–300.
  • Massa DJ, Shriner KA, Turner SR, Voit BI. Novel blends of hyperbranched polyesters and linear polymers. Macromolecules 1995;28:3214–20.
  • Osman R, Al Jamal KT, Kan PL, et al. Inhalable DNase I microparticles engineered with biologically active excipients. Pulm Pharmacol Ther 2013;26:700–9.
  • Stefanescu EA, Stefanescu C, Negulescu II. Biodegradable polymeric capsules obtained via room temperature spray drying: preparation and characterization. J Biomater Appl 2011;25:825–49.
  • Panizzon GP, Bueno FG, Ueda-Nakamura T, et al. Preparation of spray-dried soy isoflavone-loaded gelatin microspheres for enhancement of dissolution: formulation, characterization and in vitro evaluation. Pharmaceutics 2014;6:599–615.
  • Meeus J, Scurr DJ, Amssoms K, et al. Surface characteristics of spray-dried microspheres consisting of PLGA and PVP: relating the influence of heat and humidity to the thermal characteristics of these polymers. Mol Pharm 2013;10:3213–24.
  • Bhalekar M, Madgulkar A, Gunjal S, Bagal A. Formulation and optimisation of sustained release spray-dried microspheres of glipizide using natural polysaccharide. PDA J Pharm Sci Technol 2013;67:146–54.
  • Yousefi S, Emam-Djomeh Z, Mousavi SM. Effect of carrier type and spray drying on the physicochemical properties of powdered and reconstituted pomegranate juice (Punica granatum L.). J Food Sci Technol 2011;48:677–84.
  • Truong V, Bhandari BR, Howes T. Optimization of cocurrent spray drying process for sugar-rich foods. Part II - optimization of spray drying process based on glass transition concept. J Food Eng 2005;71:66–72.
  • Bourara H, Hadjout S, Benabdelghani Z, Etxeberria A. Miscibility and hydrogen bonding in blends of poly(4-vinylphenol)/poly(vinyl methyl ketone). Polymers 2014;6:2752–63.
  • Marsac PJ, Li T, Taylor LS. Estimation of drug-polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters. Pharm Res 2009;26:139–51.
  • Dhillon A, Schneider P, Kuhn G, et al. Analysis of sintered polymer scaffolds using concomitant synchrotron computed tomography and in situ mechanical testing. J Mater Sci Mater Med 2011;22:2599–605.
  • Hamilton L FR, Shakesheff KM. Development of an injectable scaffold for application in regenerative medicine to deliver stem cells and growth factors. J Pharm Pharmacol 2006:A52–3.
  • Biggs DL, Lengsfeld CS, Hybertson BM, et al. In vitro and in vivo evaluation of the effects of PLA microparticle crystallinity on cellular response. J Control Release 2003;92:147–61.
  • van Dijkhuizen-Radersma R, Hesseling SC, Kaim PE, et al. Biocompatibility and degradation of poly(ether–ester) microspheres: in vitro and in vivo evaluation. Biomaterials 2002;23:4719–29.
  • Prior S, Gander B, Blarer N, et al. In vitro phagocytosis and monocyte-macrophage activation with poly(lactide) and poly(lactide-co-glycolide) microspheres. Eur J Pharm Sci 2002;15:197–207.
  • Landreman AP, Shafer MM, Hemming JC, et al. A macrophage-based method for the assessment of the reactive oxygen species (ROS) activity of atmospheric particulate matter (PM) and application to routine (daily-24 h) aerosol monitoring studies. Aerosol Sci Technol 2008;42:946–57.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.