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Drug Development and Industrial Pharmacy Volume 9, 1983 - Issue 4
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Research Article

Azone®: A New Non-Toxic Enhancer of Cu'Taneous Penetration

Richard R. Stoughton Dept. of Dermatology, Univ. of California at San Diego, La Jolla, CA, 92103
&
William O. McClure Nelson Research and Development, 19712 MacArthur Boulevard, Irvine, CA, 92715
Pages 725-744 | Published online: 20 Oct 2008

References

  • Idson B. Percutaneous absorption. J. Pharm Sci 1975; 64: 901–924
  • McKenzie A. W., Stoughton R. B. Method for comparing percutaneous absorption of steroids. Arch Dermatol 1962; 86: 608–609
  • Otani A. S., Gange R. W., Walter J. F. Epidermal DNA synthesis: A new disc technique for evaluating incorporation of tritiated thymidine. J Invest Dermatol 1980; 75: 375–378
  • Scheuplein R., Blank I. Permeability of the skin. Physiol Rev 1971; 51: 702–747
  • Stoughton R. B. Bioassay of antimicrobials: A method of measdring penetration of agents into human skin. Arch Dermatol 1970; 101: 160–166
  • Stoughton R. B. Bioassay of formulations of topically applied glucocorticosteroids. Arch Dermatol 1972; 106: 825–827
  • Stoughton R. B. Azone (1–dodecylazacycloheptan‐2–one) enhances percutaneous penetration. Psoriasis, E. M. Farber. Grune and Stratton. 1982a; 397–398
  • Stoughton R. B. Enhanced percutaneous penetration with 1–dodecylazacycloheptan‐2–one (Azone). Arch Dermatol 1982b; Vol 7: 474–477, 118
  • Stoughton R. B., Fritsch W. E. Influence of dimethylsulfoxide (DMSO) on human percutaneous absorption. Arch Dermatol 1964; 90: 512–527
  • Walter J. F., DeQuoy P. R. Anthracene with near ultraviolet light inhibiting epidermal proliferation. Arch Dermatol 1978; 114: 1463–1465

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