24
Views
8
CrossRef citations to date
0
Altmetric
Original Article

High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Breast Cancer

, , , , , , , , , & show all
Pages 440-455 | Published online: 11 Jun 2009

References

  • Landis S H, Murray T, Bolden S. Cancer statistics, 1998. CA Cancer J Clinicians 1998; 48: 6–29
  • Henderson I C. Basic principles in the use of adjuvant therapy. Semin Oncol 1990; 17: 40–44
  • Early Breast Cancer Trialist's Collaborative Group. Systemic therapy of early breast cancer by hormonal, cytotoxic, or immune therapy. Lancet 1992; 1: 71–85
  • Antman KH., Rowlings P A, Vaughan W P. High-dose chemotherapy with autologous hematopoietic stem cell support for breast cancer in North America. J Clin Oncol 1997; 15: 1870–1879
  • National Hospital Discharge Survey for 1990 and 1991. U.S. Department of Health and Human Services. Public Health Service, Center for Disease Control. National Center for Health Statistics. Hospital Care Statistics Branch, Hyattsville, MD
  • Peters W P, Ross M, Vredenburgh J J. The use of intensive clinic support to permit outpatient autologous bone marrow transplantation for breast cancer. Semin Oncol 1994; 21: 25–31
  • Peters W P, Rogers M C. Variation in approval by insurance companies of coverage for autologous bone marrow transplantation for breast cancer. N Engl J Med 1994; 330: 473–477
  • Gale R P. Progress in acute myeloid leukemia. Ann Intern Med 1984; 101: 702–705
  • Buchner T, Hiddemann W, Loffier G. Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group. Semin Oncol 1991; 28: 76–79
  • Culbert S J, Shuster J J, Land V J. Remission induction and continuation therapy in children with their first relapse of acute lymphoid leukemia. A Pediatric Oncology Group Study. Cancer 1991; 67: 37–42
  • Kilmo M P, Connors J M. MACOP-B chemotherapy for diffuse large-cell lymphoma. Ann Intern Med 1985; 102: 596–602
  • Armitage J O, Chesson B D. Interpretation of clinical trials in diffuse large-cell lymphoma. J Clin Oncol 1988; 6: 1335–1347
  • Armitage J O. The place of third-generation regimens in the treatment of adult aggressive non-Hodgkin's lymphoma. Ann Oncol 1991; 2: 37–41
  • DeVita VT, Jr, Hubbard S M, Young R C. The role of chemotherapy in diffuse aggressive lymphomas. Semin Hematol 1988; 25: 1–10
  • Diaz P, Cabanillas R. Treatment of non-Hodgkin's lymphoma. Curr Opin Oncol 1991; 3: 830–837
  • Einhorn L H. Testicular cancer: a model for curable neoplasm. The Richard and Hilda Rosenthal Foundation Award Lecture. Cancer Res 1981; 41: 3275–3280
  • Broun E R, Nichols C R, Kneebone P. Long-term outcome of patients with relapsed and refractory germ tumors treated with high-dose chemotherapy and autologous bone marrow rescue. Ann Intern Med 1992; 117: 124–128
  • Einhom L H, Williams S D, Loehrer P J. Evaluation of optimal duration of chemotherapy in favorable prognosis disseminated germ cell tumors: a Southeastern Cancer Study Group protocol. J Clin Oncol 1989; 7: 387–391
  • Nichols C R, Tricot G, Williams S D. Dose-intensive chemotherapy in refractory germ cell cancer-a phase I/II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation. J Clin Oncol 1989; 7: 932–939
  • Einhorn L H. Treatment of testicular cancer: a new and improved model. J Clin Oncol 1990; 8: 1777–1781
  • Iancotti N I, Bosl G J. A review of the management germ cell tumors: evolution of a curative treatment program. Cancer Invest 1990; 8: 173–179
  • Adelstein D J, Sharan V M, Earle A S. Long-term results after chemoradiotherapy for locally confined squamous-cell head and neck cancer. Am J Clin Oncol 1990; 13: 440–447
  • Piver M S. Ovarian carcinoma. A decade of progress. Cancer 1984; 54: 2706–2715
  • Young R C. Mechanisms to improve chemotherapy effectiveness. Cancer 1990; 65: 815–822
  • DePree N, Wils J. Long-term survival of patients with advanced ovarian carcinoma treated with cisplatin based chemotherapy regimens. Anticancer Res 1989; 9: 1869–1871
  • Stiff P J, Bayer R, Kerger C. High dose chemotherapy with autologous transplantation for persistent, relapsed ovarian cancer: a multivariate analysis of survival for 100 consistently treated patients. J Clin Oncol 1997; 15: 1309–1317
  • Henderson I C, Canellos G P. Cancer of the breast over the past decade. N Engl J Med 1980; 302: 78–90
  • Early Breast Cancer Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. Lancet 1992; 1: 1–15; 71–85
  • Fisher B, Brown A M, Dimitrov N V. Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen non responsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol 1990; 8: 1482–1496
  • Fisher B, Redmond C, Legault-Poisson S. Postoperative chemotherapy and tamoxifen compared with tamoxifen alone in the treatment of positive-node breast cancer patients aged 50 years and older with tumors responsive to tamoxifen: results from the National Surgical Adjuvant Breast and Bowel Project B-16. J Clin Oncol 1990; 8: 1005–1018
  • Henderson I C. Adjuvant systemic therapy: state of the art, 1989. Breast Cancer Res Treat 1989; 15: 3–22
  • Schabel F M. Animal models as predictive systems. Cancer Chemotherapy: Fundamental and Recent Advances. Year Book Medical Publishers, Chicago 1975; 323
  • Skipper H E, Schabel F M, Janey R. Experimental evaluation of anti-tumor agents. Cancer Chemother Rep 1961; 35: 1–35
  • Frei E, Canellos G C. Dose: a critical factor in cancer therapy. Am J Med 1980; 69: 585–594
  • Peters W P, Dansey R. New concepts in the treatment of breast cancer using high-dose chemotherapy. Cancer Chemother Pharmacol 1997; 40: S88–93
  • Goldie J H, Coldman A J. A mathematic model for relating the drug sensitivity of tumors to the spontaneous mutation rate. Cancer Treat Rep 1979; 63: 1727–1733
  • Priestman T, Baum M, Jones V. Treatment and survival in advanced breast cancer. B Med J, 2: 1673–1674
  • Powell T G, Sniff I E, Ford H T. Failure of chemotherapy to prolong survival in a group of patients with metastatic breast cancer. Lancet 1980; 1: 580–582
  • Frei E. Pharmacologic strategies for high-dose chemotherapy. High Dose Cancer Therapy: Pharmacology, Hematopoietisis, Stem Cells, JO Armitage. Williams & Wilkins, Baltimore 1992; 3–13
  • Schabel FM, Jr, Skipper H E, Trader M W. Establishment of cross-resistance profiles for new agents. Cancer Treat Rep 1983; 57: 905–922
  • Schabel F M, Trader M W, Laster W R. Patterns of resistance and therapeutic synergism among alkylating agents. Antibiot Chemother 1978; 23: 200–215
  • Jones R B, Shpall E J, Ross M. High-dose carboplatin, cyclophosphamide, and BCNU with autologous bone marrow support: excessive hepatic toxicity. Cancer Chemother Pharmacol 1990; 26: 155–156
  • Egorin M J, Cohen B E, Herzig R H. Human plasma pharmacokinetics and urinary excretion of thiotepa and its metabolites in patients receiving high-dose thiotepa therapy. Advances in Cancer Chemotherapy: High-dose Thiotepa and Autologous Marrow Transplantation, GP Herzig. Park Row Publishers, New York 1987
  • Thomas E D, Storb R, Clift R A. Bone marrow transplantation. N Engl J Med 1975; 292: 832–895
  • Thomas E D, Buckner C D, Clift R A. Marrow transplantation for acute nonlymphoblastic leukemia in first remission. N Engl J Med 1979; 301: 597–599
  • Hryniuk W, Bush H. The importance of dose intensity in chemotherapy for metastatic breast cancer. J Clin Oncol 1984; 2: 1281–1288
  • Henderson I C, Hayes D F, Gelman R. Dose response in the treatment of breast cancer. J Clin Oncol 1988; 6: 1501–1515
  • Peters W P. High-dose chemotherapy and autologous bone marrow support for breast cancer. Important Advances in Oncology, VT DeVita, S Hellman, SA Rosenberg. J.B. Lippincott, Philadelphia 1991; 135–150
  • Tannock I, Boyd N, DeBoer G. A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer. J Clin Oncol 1988; 6: 1377–1387
  • Perkins J B, Fields K K, Elfenbein G J. Ifosfamide/carboplatin/etoposide chemotherapy for metastatic breast cancer with or without autologous hematopoietic stem cell transplantation: evaluation of dose-response relationships. Semin Oncol 1995; 22(3 Suppl 7)5–8
  • Winer E, Berry D, Duggan D. Failure of higher dose paclitaxel to improve outcome in patients with metastatic breast cancer—results from CALGB 9342. Proc Am Soc Clin Oncol 1998; 17: 101a, abstract
  • Henderson I C. Chemotherapy for advanced disease. Breast Diseases, JR Harris. J.B. Lippincott, Philadelphia 1987; 428–479
  • Peters W P, Eder J P, Schryber S. High-dose combination alkylating agents with autologous bone marrow support: a phase I trial. J Clin Oncol 1986; 4: 646–654
  • Eder J P, Antman, Peters W P. High dose combination alkylating agent chemotherapy with autologous bone marrow support for metastatic breast cancer. J Clin Oncol 1986; 4: 1592–1597
  • Antman K, Bearman S I, Davidson. Dose intensive therapy in breast cancer: current status. New Strategies in Bone Marrow Transplantation, RP Gale, RE Champlin. Alan R. Liss, New York 1990; 423–436
  • Peters W P, Shpall E J, Jones R B. High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer. J Clin Oncol 1988; 6: 1368–1376
  • Peters W P. Autologous bone marrow transplantation for breast cancer. Bone Marrow Transplantation, SJ Forman, KG Blume, ED Thomas. Blackwell Scientific Publications., Cambridge 1994; 789–801
  • Gisselbrecht C, LePage E, Extra J. Inflammatory and metastatic breast cancer: cyclophosphamide and total body irradiation (TBI) with autologous bone marrow transplantation (ABMT). Autologous Bone Marrow Transplantation. Procedeings of the Fourth International Symposium, K Dicke, G Spitzer, S Jagannath. M.D. Anderson Cancer Center Press, Houston 1989; 363–367
  • Peters W P, Shpall E J, Jones R B. High-dose combination cyclophosphamide, cisplatin, and carmustine with bone marrow support as initial treatment for metastatic breast cancer: three to six year follow-up. Proc Am Soc Clin Oncol 1990; 9: 10
  • Moonneier J A, Williams S F, Kaminer L S. High dose trialkylator chemotherapy with autologous stem cell rescue in patients with refractory malignancies. J Natl Cancer Inst 1990; 82: 29–34
  • Kennedy M J, Beveridge R A, Rowley S D. High-dose chemotherapy with reinfusion of purged autologous bone marrow following dose intense induction as initial therapy for metastatic breast cancer. J Natl Cancer Inst 1991; 83: 920–926
  • Eddy D M. Review article. High-dose chemotherapy with autologous bone marrow transplantation for the treatment of metastatic breast cancer. J Clin Oncol, 10: 657–670
  • Antman K, Ayash Elias L. A. A phase II study of high dose cyclophosphamide, thiotepa, and carboplatin with autologous marrow support in women with measureable advanced breast cancer responding to standard-dose therapy. J Clin Oncol 1992; 10: 102–110
  • Williams S F, Gilewski T, Mick R. High-dose consolidation therapy with autologous stem-cell rescue in stage IV breast cancer: follow-up report. J Clin Oncol 1992; 10: 1743–1747
  • Klumpp T R, Mangan K F, Glenn L D. Phase II pilot study of high-dose busulfan and CY followed gy autologous BM or peripheral blood stem cell transplantation in patients with advanced chemosensitive breast cancer. Bone Marrow Transplant 1993; 11: 337–339
  • Myers S E, Mick R, Williams S F. High-dose chemotherapy with autologous stem cell rescue in women with metastatic breast cancer with involved bone marrow: a role for peripheral blood progenitor transplant. Bone Marrow Transplant 1994; 13: 449–454
  • Lazarus H M, Gray R., Ciobanu N. A phase I trial of high-dose melphalan, high-dose etoposide, and autologous bone marrow re-infusion in solid tumors: an Eastern Cooperative Oncology Group (ECOG) study. Bone Marrow Transplant 1994; 14: 443–448
  • Weaver C H, Bensinger W I, Appelbaum F R. Phase I study of high-dose busulfan, melphalan and thiotepa with autologous stem cell support in patients with refractory malignancies. Bone Marrow Transplant 1994; 14: 813–819
  • Somlo G, Doroshow J H, Forman S J. High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer. Cancer 1994; 73: 1678–1685
  • Somlo G, Doroshow J H, Forman S J. High-dose cisplatin, etoposide, and cyclophosphamide with autologous stem cell reinfusion in patients with responsive metastatic or high-risk primary breast cancer. Cancer 1994; 73: 125–134
  • Vaughan W P, Reed E C, Edwards B. High-dose cyclophosphamide, thiotepa and hydroxyurea with autologous hematopoietic stem cell rescue: an effective consolidation chemotherapy regimen for early metastatic breast cancer. Bone Marrow Transplant 1994; 13: 619–624
  • Saez R A, Selby G B, Slease R B. Autologous bone marrow transplantation for metastatic breast cancer. J Okla State Med Assoc 1994; 87: 405–410
  • Fields K K, Elfenbein G J, Lazarus H M. Maximum tolerated doses of ifosfamide, carboplatin, and etoposide given over six days followed by autolobous stem cell rescue: toxicity profile. J Clin Oncol 1995; 13: 323–332
  • Kalaycioglu M E, Lichtin A E, Andresen S W. High-dose busulfan and cyclophosphamide followed by autologous bone marrow transplantation and/or peripheral blood progenitor cell rescue for metastatic breast cancer. Am J Clin Oncol 1994; 18: 491–494
  • Spitzer T R, Cirenza E, McAfee S. Phase I-II trial of high-dose cyclophosphamide, carboplatin and autologous bone marrow or peripheral blood stem cell rescue. Bone Marrow Transplant 1995; 15: 537–542
  • Gisselbrecht C, Extra J M, Lotz J P. Cyclophosphamide/mitoxantrone/melphalan (CMA) regimen prior to autologous bone marrow transplantation (ABMT) in metastatic breast cancer. Bone Marrow Transplant 1996; 18: 857–863
  • DeMagalhaes-Silverrnan M, Rybka W B, Lembersky B. High-dose cyclophosphamide, carboplatin. and etoposide with autologous stem cell rescue in patients with breast cancer. Am J Clin Oncol 1996; 19: 169–173
  • Stemmer S M, Cagnoni P J, Shpall E J. High-dose paclitaxel, cyclophosphamide, and cisplatin with autologous hematopoietic progenitor-cell support: a phase I trial. J Clin Oncol 1996; 14: 1463–1472
  • Demirer T, Buckner C D, Appelbaum F R. High-dose busulfan and cyclophosphamide followed by autologous transplantation in patients with advanced breast cancer. Bone Marrow Transplant 1996; 17: 769–774
  • De Vries E G, Rodenhuis S, Schouten H C. Phase II study of intensive chemotherapy with autologous bone marrow transplantation in patients in complete remission of disseminated breast cancer. Breast Cancer Res Treat 1996; 39: 307–313
  • Perkins J B, Effenbein G J, Fields K K. Analysis of dose-response relationships in the setting of high-dose ifosfamide. carboplatin, and etoposide and autologous hematopoietic stem cell transplantation: implications for the treatment of patients with advanced breast cancer. Semin Oncol 1996; 23: 42–46
  • Bezwoda WR, Seymour L, Dansey R D. High-dose chemotherapy with hematopoietic rescue as primary treatment for metastatic breast cancer: a randomized trial. J Clin Oncol 1995; 13: 2483–2489
  • Peters W P, Jones R B, Vredenburgh J. A large, prospective, randomized trial of high-dose combination alkylating agent (CPB) with autologous cellular support (ABMS) as consolidation for patients with metastatic breast cancer achieving complete remission after intensive doxorubicin-based induction therapy (AFM). Proc Am Soc Clin Oncol 1996; 15: 149a
  • Peters W P, Jones R B, Vredenburgh J. A large, prospective, randomized trial of high-dose combination alkylating agent (CPB) with autologous cellular support (ABMS) as consolidation for patients with metastatic breast cancer achieving complete remission after intensive doxorubicin-based induction therapy (AFM). Cancer Res Treat 1996; 37: 35
  • Lazarus H M. Hematopoietic progenitor cell transplantation in breast cancer: current status and future directions. Cancer Invest 1998; 16: 102–126
  • Rohman Z U, Frye D K, Buzdar A U. Impact of selection process on response rate and long-term survival of potential high-dose chemotherapy candidates treated with standard-dose doxorubicin-containing chemotherapy in patients with metastatic breast cancer. J Clin Oncol 1997; 15: 3171–3177
  • Zambetti M, Valugussa P, Bonadonna G. Eight-year results with adjuvant intravenous CMF in nodenegative (N-) and estrogen receptor negative (ER-) breast cancer. Proc Am Soc Clin Oncol 1992; 11: 69a
  • Budman D R, Wood W, Henderson I C. Initial findings of CALGB 8541: a dose and dose intensity trial of cyclophosphamide (C), doxorubicin (A), and 5-fluorourcal (F) as adjuvant treatment of stage II, node + female breast cancer. Proc Am Soc Clin Oncol 1992; 11: 29a
  • Muss HB., Thor A D, Berry D A. cerbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 1994; 330: 1260–1266
  • Bhardwaj S, Holland J F, Norton L. An intensive sequenced adjuvant chemotherapy regimen for breast cancer. Cancer Invest 1993; 11: 6–9
  • Fisher B, Anderson S., Wickerham D L. Increased intensification and total dose of cyclophosphamide in a doxorubicin-cyclophosphamide regimen for the treatment of primary breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-22. J Clin Oncol 1997; 15: 1858–1869
  • Henderson I, Berry C., Demetri D. G. Improved disease free and overall survival from the addition of sequential paclitaxel but not from the escalation of doxorubicin dose level in the adjuvant chemotherapy of patients with node-positive primary breast cancer. Proc Am Soc Clin Oncol 1998; 17: 101a
  • Robert N J, Gray R, Gelber R D. Node positive (N+) breast cancer: which patients are at high risk. Proc Am Soc Clin Oncol 1991; 10: 111a
  • Peters W P, Ross M, Vredenburgh J J. High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer. J Clin Oncol 1993; 11: 1132–1143
  • Gianni A M, Siena S, Bregni M. Growth factor supported high-dose sequential (HDS) adjuvant chemotherapy in breast cancer with ≥ 10 positive nodes. Proc Am Soc Clin Oncol 1992; 11: 60
  • Peters W P, Dansey R, Klein J. High-dose chemotherapy for high-risk primary breast cancer. Adjuvant Therapy of Cancer VIII, SE Salmon. Lippincott-Raven, Philadelphia 1997; 117–122
  • Gianni A M, Siena S, Bregni M. Efficacy, toxicity, and applicability of high-dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: five-year results. J Clin Oncol 1997; 15: 2312–2321
  • Razis E D, Samonis G, Cook P. TMJ: a well-tolerated high-dose regimen for the adjuvant chemotherapy of high risk breast cancer. J Med 1994; 25: 241–250
  • Peters W P, Fay J W, Holland H K. Autologous bone marrow transplantation as adjuvant therapy in primary breast cancer: the American experience. Bone Marrow Transplant 1995; 15: S254–S259, (Suppl 1)
  • Holland H K, Dix S P, Geller R B. Minimal toxicity and mortality in high-risk breast cancer patients receiving high-dose cyclophosphamide, thiotepa, and carboplatin plus autologous marrow/stem-cell transplantation and comprehensive supportive care. J Clin Oncol 1996; 14: 1156–1164
  • Thomas J, Perez- F., Carrion R, Escudero A. Results of a pilot study of 40 patients using high-dose therapy with hematopoetic rescue after standard-dose adjuvant therapy for high-risk breast cancer. Bone Marrow Transplant 1997; 19: 331–336
  • Rodenhuis S, Van der Wall Richel D J. A randomized trial of high-dose chemotherapy and hematopoietic progenitor cell support in operable breast cancer with extensive axillary lymph node involvement. Proc Am Soc Clin Oncol 1998; 17: 123a
  • Rodenhuis S, Richel D, Van der Wall E. Randomized trial of high-dose chemotherapy and haematopoietic progenitor-cell support in operable breast cancer with extensive axillary lymphnode involvement. Lancet 1998; 352: 515–521
  • Hryniuk Frei W. E, III, Wright F A. A single scale for comparing dose-intensity of all chemotherapy regimens in breast cancer: summation dose-intensity. J Clin Oncol 1998; 16: 137–3147
  • Garcia-Carbonero R, Hidalgo M, Paz-Ares L. Patient selection in high-dose chemotherapy trials: relevance in high-risk breast cancer. J Clin Oncol 1997; 15: 3178–3184
  • Hortobagyi G N, Buzdar A U, Chemplin R. Lack of efficacy of adjuvant high-dose tandem combination chemotherapy for high risk primary breast cancer—a randomized trial. Proc Am Soc Clin Oncol 1998; 17: 123a
  • Pustztai L, Hortabagyi G N. Discouraging news for high-dose chemotherapy in high-risk breast cancer. Lancet 1998; 352: 501–502
  • Vahdat L, Antman K. High-dose chemotherapy with autologous stem cell support for breast cancer. Curr Opin Hematol 1997; 4: 381–389
  • Viens P, Penault-Llorca F, Jacquemier J. High-dose chemotherapy and hematopoietic stem cell transplantation for inflammatory breast cancer: pathologic response and outcome. Bone Marrow Transplant 1998; 21: 249–254
  • Cagnoni P J, Nieto Y, Shpall E J. High-dose chemotherapy with autologous hematopoietic progenitor-cell support as part of combined modality therapy in patients with inflammatory breast cancer. J Clin Oncol 1998; 16: 1661–1668
  • Miller A, Khosla P, Lynch J. Durable remission of locally advanced breast cancer with multimodality management. Med Oncol 1998; 15: 89–95
  • Kennedy M J, Vogelsang G B, Jones R J. Phase I trial of interferon gamma to potentiate cyclosporine-induced graft-ver-sus-host disease in woman undergoing autologous bone marrow transplantation for breast cancer. J Clin Oncol 1994; 12: 249–257
  • Margolin K A, Wright C, Forman S J. Autologous bone marrow purging by in situ IL-2 activations of endogenous killer cells. Leukemia 1997; 11: 723–728
  • Baynes R D, Wood G W, Skikne B S. Combining dose intensive chemotherapy with specific adoptive immunotherapy in metastic breast cancer. Breast Cancer Res Treat 1997; 46: 68, 270a
  • Eibl B, Schwaighofer H, Nachbaur D. Evidence for a gratt-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer. Blood 1996; 88: 1501–1508
  • Ueno N T, Rondon G, Mirza N Q. Allogeneic peripheral blood progenitor cell transplantation for poor risk patients with metastatic breast cancer. J Clin Oncol 1998; 16: 986–993
  • Or R, Ackerstein A, Nagler A. Allogeneic cell-mediated immunotherapy for breast cancer after autologous stem cell transplantation: a clinical pilot study. Cytokines Cell Mol Ther 1998; 1: 1–6
  • Winer E, Lindley C, Hardee M. Quality of life (QL) assessment in patients with breast cancer surviving 12 months or more following high dose chemotherapy with autologous bone marrow transplant (HDCABMT). Proc Am Soc Clin Oncol 1 1992; 1: 383a
  • Peters W P, Kurtzberg J, Romber G. Comparative effects of G-CSF and GM-CSF on primary peripheral, blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Blood 1993; 81: 1709–1719
  • Hann D M, Jacobsen P B, Martin S C. Quality of life following bone marrow transplantation for breast cancer: a comparative study. Bone Marrow Transplant 1997; 19: 257–264
  • Hann D M, Jacobsen P B, Martin S C. Fatigue in women treated with bone marrow transplantation for breast cancer: a comparison with women with no history of cancer. Support Care Cancer 1997; 5: 44–52
  • Ahles T A, Tope D M, Furstenberg C. psychologic and neu-ropsychologic impact of autologous bone marrow transplantation. J Clin Oncol 1996; 14: 1457–1462
  • McQuellon R P, Craven B, Russell G B. Quality of life in breast cancer patients before and after autologous bone marrow transplantation. Bone Marrow Transplant 1996; 18: 1579–1584
  • Stone R M, Neuberg D, Saiffer R. Myelodysplastic syndrome as a late complication following autologous bone marrow transplantation for non-Hodgkins lymphoma. J Clin Oncol 1994; 12: 2535–2542
  • Darrington D L, Vose J M, Anderson J R. Incidence and characterization of secondary myelodysplastic syndrome following high-dose chemoradiotherapy and autologous stem-cell transplantation from lymphoid malignancies. J Clin Oncol 1994; 12: 2527–2534
  • Schwartzberg L S, Birch R, West W H. Sequential treatment including high-dose chemotherapy with peripheral blood stem cell support in patients with high-risk stage II-1II breast cancer. Am J Clin Oncol 1998; 21: 523–531
  • Laughlin M, McGaughey D S, Crews J R. Secondary myelodysplasia and acute leukemia in breast cancer patients with autologous bone narrow transplant. J Clin Oncol 1998; 16: 1008–1012
  • Hillner B E, Smith T J, Desch C E. Efficacy and cost effectiveness of autologous bone marrow transplantation in metastatic breast cancer-estimates using decision analysis while awaiting clinical trial results. JAMA 1992; 267: 2055–2061
  • Lawless G D. Cost-effectiveness of autologous bone marrow transplantation. Am. J Health Syst Pharm 1995; 52: S11–14

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.