Three Vascular Endothelial Growth Factor Polymorphisms (-460C>T, -2578C>A, 1612G>A) with Cancer Risk: A Meta-Analysis Based on 30 Case-Control Studies

REFERENCES

• Thakkinstian A, McElduff P, D'Este C, Duffy D, Attia J. A method for meta-analysis of molecular association studies. Stat Med 2005;24:1291–306.
   PubMed Web of Science ®Google Scholar
• Galimberti S, Nagy B, Palumbo GA, Ciancia E, Buda G, Orciuolo E, Melosi A, Lambelet P, Ronca F, Petrini M. Vascular endothelial growth factor polymorphisms in mantle cell lymphoma. Acta Haematol 2010;123:91–95.
   PubMed Web of Science ®Google Scholar
• Guan X, Zhao H, Niu J, Tang D, Ajani JA, Wei Q. The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. BMC Gastroenterol 2009;9:77.
   PubMedGoogle Scholar
• Ke Q, Liang J, Wang LN, Hu ZB, Jin GF, Zhou Y, Wang JM, Tan YF, Hua ZL, Xu YC, Shen J, Shen HB. Potentially functional polymorphisms of the vascular endothelial growth factor gene and risk of gastric cancer. Mol Carcinog 2008;47:647–651.
   PubMed Web of Science ®Google Scholar
• Langsenlehner U, Wolf G, Langsenlehner T, Gerger A, Hofmann G, Clar H, Wascher TC, Paulweber B, Samonigg H, Krippl P, Renner W. Genetic polymorphisms in the vascular endothelial growth factor gene and breast cancer risk. The Austrian “tumor of breast tissue: incidence, genetics, and environmental risk factors study.” Breast Cancer Res Treat 2008;109:297–304.
   PubMed Web of Science ®Google Scholar
• Balasubramanian SP, Cox A, Cross SS, Higham SE, Brown NJ, Reed MW. Influence of VEGF-A gene variation and protein levels in breast cancer susceptibility and severity. Int J Cancer 2007;121:1009–1016.
   PubMed Web of Science ®Google Scholar
• Pharoah PD, Tyrer J, Dunning AM, Easton DF, Ponder BA. Association between common variation in 120 candidate genes and breast cancer risk. PLoS Genet 2007;3:e42.
   PubMed Web of Science ®Google Scholar
• Kataoka N, Cai Q, Wen W, Shu XO, Jin F, Gao YT, Zheng W. Population-based case-control study of VEGF gene polymorphisms and breast cancer risk among Chinese women. Cancer Epidemiol Biomarkers Prev 2006;15:1148–1152.
   PubMed Web of Science ®Google Scholar
• Jacobs EJ, Feigelson HS, Bain EB, Brady KA, Rodriguez C, Stevens VL, Patel AV, Thun MJ, Calle EE. Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort. Breast Cancer Res 2006;8:R22.
   PubMed Web of Science ®Google Scholar
• Jin Q, Hemminki K, Enquist K, Lenner P, Grzybowska E, Klaes R, Henriksson R, Chen B, Pamula J, Pekala W, Zientek H, Rogozinska-Szczepka J, Utracka-Hutka B, Hallmans G, Forsti A. Vascular endothelial growth factor polymorphisms in relation to breast cancer development and prognosis. Clin Cancer Res 2005;11:3647–3653.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Li N, Zhuang W, Wu X. Vascular endothelial growth factor (VEGF) gene polymorphisms and gastric cancer risk in a chinese han population. Mol Carcinog 2010;50:184–188.
   PubMed Web of Science ®Google Scholar
• Al-Moundhri MS, Al-Nabhani M, Burney IA, Al-Farsi AA, Al-Bahrani B. Gastric cancer risk predisposition and prognostic significance of vascular endothelial growth factor (VEGF) gene polymorphisms–a case-control study in an Omani population. Mol Carcinog 2009;48:1170–1176.
   PubMed Web of Science ®Google Scholar
• Tahara T, Shibata T, Nakamura M, Yamashita H, Yoshioka D, Hirata I, Arisawa T. Effect of polymorphisms in the 3′ untranslated region (3′-UTR) of vascular endothelial growth factor gene on gastric cancer and peptic ulcer diseases in Japan. Mol Carcinog 2009;48:1030–1037.
   PubMed Web of Science ®Google Scholar
• Tzanakis N, Gazouli M, Rallis G, Giannopoulos G, Papaconstantinou I, Theodoropoulos G, Pikoulis E, Tsigris C, Karakitsos P, Peros G, Nikiteas N. Vascular endothelial growth factor polymorphisms in gastric cancer development, prognosis, and survival. J Surg Oncol 2006;94:624–630.
   PubMed Web of Science ®Google Scholar
• Chae YS, Kim JG, Sohn SK, Cho YY, Moon JH, Bae HI, Park JY, Lee MH, Lee HC, Chung HY, Yu W. Investigation of vascular endothelial growth factor gene polymorphisms and its association with clinicopathologic characteristics in gastric cancer. Oncology 2006;71:266–272.
   PubMed Web of Science ®Google Scholar
• Dassoulas K, Gazouli M, Rizos S, Theodoropoulos G, Christoni Z, Nikiteas N, Karakitsos P. Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival. Mol Carcinog 2009;48:563–569.
   PubMed Web of Science ®Google Scholar
• Maltese P, Canestrari E, Ruzzo A, Graziano F, Falcone A, Loupakis F, Tonini G, Santini D, Magnani M. VEGF gene polymorphisms and susceptibility to colorectal cancer disease in Italian population. Int J Colorectal Dis 2009;24:165–170.
   PubMed Web of Science ®Google Scholar
• Cacev T, Loncar B, Seiwerth S, Spaventi S, Kapitanovic S. Vascular endothelial growth factor polymorphisms -1154 G/A and -460 C/T are not associated with VEGF mRNA expression and susceptibility to sporadic colon cancer. DNA Cell Biol 2008;27:569–574.
   PubMed Web of Science ®Google Scholar
• Hofmann G, Langsenlehner U, Renner W, Langsenlehner T, Yazdani-Biuki B, Clar H, Gerger A, Wehrschuetz M, Samonigg H, Krippl P. Common single nucleotide polymorphisms in the vascular endothelial growth factor gene and colorectal cancer risk. J Cancer Res Clin Oncol 2008;134:591–595.
   PubMed Web of Science ®Google Scholar
• Zhang L, Zhang G, Wang P, Gong J, Cao Y, Tang L. Association of vascular endothelial growth factor -2578C/A gene polymorphism in Chinese patients with colon cancer. Genet Test Mol Biomarkers 2010;15:117–121.
   PubMed Web of Science ®Google Scholar
• Onen IH, Konac E, Eroglu M, Guneri C, Biri H, Ekmekci A. No association between polymorphism in the vascular endothelial growth factor gene at position -460 and sporadic prostate cancer in the Turkish population. Mol Biol Rep 2008;35:17–22.
   PubMed Web of Science ®Google Scholar
• VanCleave TT, Moore JH, Benford ML, Brock GN, Kalbfleisch T, Baumgartner RN, Lillard JW, Kittles RA, Kidd LC. Interaction among variant vascular endothelial growth factor (VEGF) and its receptor in relation to prostate cancer risk. Prostate 2010, 70:341–352.
   PubMed Web of Science ®Google Scholar
• Bruyere F, Hovens CM, Marson MN, d'Arcier BF, Costello AJ, Watier H, Linassier C, Ohresser M. VEGF polymorphisms are associated with an increasing risk of developing renal cell carcinoma. J Urol 2010, 184:1273–1278.
   PubMed Web of Science ®Google Scholar
• Hsiao PJ, Lu MY, Chiang FY, Shin SJ, Tai YD, Juo SH. Vascular endothelial growth factor gene polymorphisms in thyroid cancer. J Endocrinol 2007;195:265–270.
   PubMed Web of Science ®Google Scholar
• Li Y, Wang Y, Kang S, Wang N, Zhou RM, Duan YN, Sun DL, Qin JJ, Zhao W, Zhao L. Association of vascular endothelial growth factor gene polymorphisms with susceptibility to epithelial ovarian cancer. Int J Gynecol Cancer 2010, 20:717–723.
   PubMed Web of Science ®Google Scholar
• Konac E, Onen HI, Metindir J, Alp E, Biri AA, Ekmekci A. Lack of association between -460 C/T and 936 C/T of the vascular endothelial growth factor and angiopoietin-2 exon 4 G/A polymorphisms and ovarian, cervical, and endometrial cancers. DNA Cell Biol 2007;26:453–463.
   PubMed Web of Science ®Google Scholar
• Kim YH, Kim MA, Park IA, Park WY, Kim JW, Kim SC, Park NH, Song YS, Kang SB. VEGF polymorphisms in early cervical cancer susceptibility, angiogenesis, and survival. Gynecol Oncol 2010, 119:232–236.
   PubMed Web of Science ®Google Scholar
• Zhai R, Liu G, Zhou W, Su L, Heist RS, Lynch TJ, Wain JC, Asomaning K, Lin X, Christiani DC. Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer. Clin Cancer Res 2008;14:612–617.
   PubMed Web of Science ®Google Scholar
• Lee SJ, Lee SY, Jeon HS, Park SH, Jang JS, Lee GY, Son JW, Kim CH, Lee WK, Kam S, Park RW, Park TI, Kang YM, Kim IS, Jung TH, Park JY. Vascular endothelial growth factor gene polymorphisms and risk of primary lung cancer. Cancer Epidemiol Biomarkers Prev 2005;14:571–575.
   PubMed Web of Science ®Google Scholar
• Zhai R, Liu G, Asomaning K, Su L, Kulke MH, Heist RS, Nishioka NS, Lynch TJ, Wain JC, Lin X, Christiani DC. Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk. Carcinogenesis 2008;29:2330–2334.
   PubMedGoogle Scholar
• Howell WM, Bateman AC, Turner SJ, Collins A, Theaker JM. Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma. Genes Immun 2002;3:229–232.
   PubMed Web of Science ®Google Scholar
• Garcia-Closas M, Malats N, Real FX, Yeager M, Welch R, Silverman D, Kogevinas M, Dosemeci M, Figueroa J, Chatterjee N, Tardon A, Serra C, Carrato A, Garcia-Closas R, Murta-Nascimento C, Rothman N, Chanock SJ. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet 2007;3:e29.
   PubMed Web of Science ®Google Scholar
• Koukourakis MI, Papazoglou D, Giatromanolaki A, Bougioukas G, Maltezos E, Sivridis E. VEGF gene sequence variation defines VEGF gene expression status and angiogenic activity in non-small cell lung cancer. Lung Cancer 2004;46:293–298.
   PubMed Web of Science ®Google Scholar