149
Views
3
CrossRef citations to date
0
Altmetric
Original Articles

Association of RUNX3 Methylation with Clinical Outcome and Cell Migration/Invasion in Laryngeal Squamous Cell Carcinoma

, , &
Pages 105-113 | Received 24 Jan 2015, Accepted 03 Oct 2015, Published online: 06 Feb 2016

References

  • Cattaruzza MS, Maisonneuve P, Boyle P. Epidemiology of laryngeal cancer. Eur J Cancer B Oral Oncol 1996;32B:293–305.
  • Chen K, Song F, He M, Li H, Qian B, Zhang W, et al. Trends in head and neck cancer incidence in Tianjin, China, between 1981 and 2002. Head Neck 2009;31:175–182.
  • Morshed K, Polz-Dacewicz M, Szymanski M, Polz D. Short-fragment PCR assay for highly sensitive broad-spectrum detection of human papillomaviruses in laryngeal squamous cell carcinoma and normal mucosa: clinico-pathological evaluation. Eur Arch Otorhinolaryngol 2008;265(Suppl 1):S89–S96.
  • Li Z, Gao W, Lei W, Ho W, Chan Y, Wong T, et al. The diagnostic value of methylated DNA in laryngeal squamous cell carcinoma: meta-analysis. Head Neck Oncol 2013;5:15.
  • Kada S, Hirano S, Tateya I, Kitamura M, Ishikawa S, Kanda T, et al. Ten years single institutional experience of treatment for advanced laryngeal cancer in Kyoto University. Acta Otolaryngol Suppl 2010;563:68–73.
  • Stembalska A, Leszczyński P, Gil J, Ramsey D, Pitala G, Maciejczyk A, et al. Global DNA methylation status in laryngeal cancer. Head Neck. 2014;36:419–424.
  • Wong TS, Gao W, Li ZH, Chan JY, Ho WK. Epigenetic dysregulation in laryngeal squamous cell carcinoma. J Oncol 2012;2012:739461.
  • Markowski J, Sieron AL, Kasperczyk K, Ciupinska-Kajor M, Augusciak-Duma A, Likus W. Expression of the tumor suppressor gene hypermethylated in cancer 1 in laryngeal carcinoma. Oncol Lett 2015;9:2299–2302.
  • Furuta T, Shuto T, Shimasaki S. DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription. BMC Mol Biol 2008;9:39.
  • Severin PM, Zou X, Gaub HE, Schulten K. Cytosine methylation alters DNA mechanical properties. Nucleic Acids Res 2011;39:8740–8751.
  • Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000;16:168–174.
  • Wu CT, Morris JR. Genes, genetics and epigenetics: a correspondence. Sciences 2001;293:1103–1105.
  • Ito Y. Oncogenic potential of the RUNX gene family: overview. Oncogene 2004;23:4198–4208.
  • Li QL, Ito K, Sakakura C, Fukamachi H, Noue K, Chi XZ. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 2002;109:113–124.
  • Yanada M, Yaoi T, Shimada J, Sakakura C, Nishimura M, Ito K. Frequent hemizygous deletion at 1p36 and hypermethylation down-regulate RUNX3 expression in human lung cancer cell lines. Oncol Rep 2005;14:817–822.
  • Sakakura C, Miyagawa K, Fukuda KI, Nakashima S, Yoshikawa T, Kin S. Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis. Oncogene 2007;26:5927–5938.
  • Zhang XY, He HR, Zhang X, Guo WJ, Wang YQ. RUNX3 promoter methylation is associated with hepatocellular carcinoma risk: a meta-analysis. Cancer Invest 2015;33:121–125.
  • Tan SH, Ida H, Lau QC, Goh BC, Chieng WS, Loh M, et al. Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3. Oncol Rep 2007;18:1225–1230.
  • Nishio M, Sakakura C, Nagata T, Komiyama S, Miyashita A, Hamada T. RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker. Anticancer Res 2010;30:2673–2682.
  • Marioni G, Marchese-Ragona R, Cartei G, Marchese F, Staffieri A. Current opinion in diagnosis and treatment of laryngeal carcinoma. Cancer Treat Rev 2006;32:504–515.
  • Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 2010;17:1471–1474.
  • Wang D, Cui W, Wu X, Qu Y, Wang N, Shi B, et al. RUNX3 site-specific hypermethylation predicts papillary thyroid cancer recurrence. Am J Cancer Res 2014;4:725–737.
  • Xu Y, Wang K, Gao W, Zhang C, Huang F, Wen S, et al. MicroRNA-106b regulates the tumor suppressor RUNX3 in laryngeal carcinoma cells. FEBS Lett 2013;587:3166–3174.
  • Kim TY, Lee HJ, Hwang KS, Lee M, Kim JW, Bang YJ, et al. Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma. Lab Invest 2004;84:479–484
  • Tang J, Bai W, Ji W, Gao H, Liu J. Relationship between hypermethylation of Runx3 gene and the development and metastasis of laryngeal carcinoma. J Clin Otorhinolaryngol Head and Neck Surg. 2010;24:834–837.
  • Subramaniam MM, Chan JY, Yeoh KG, Quek T, Ito K, Salto-Tellez M. Molecular pathology of RUNX3 in human carcinogenesis. Biochim Biophys Acta 2009;1796:315–331.
  • Pennison M, Pasche B. Targeting transforming growth factor-beta signaling. Curr Opin Oncol 2007;19:579–585
  • Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF, Sporn MB. Type beta transforming growth factor: a bifunctional regulator of cellular growth. Proc Natl Acad Sci USA 1985;82:119–123
  • Connolly EC, Freimuth J, Akhurst RJ. Complexities of TGF-beta targeted cancer therapy. Int J Biol Sci 2012;8:964–978
  • Chen F, Bai J, Li W, Mei P, Liu H, Li L, et al. RUNX3 suppresses migration, invasion and angiogenesis of human renal cell carcinoma. PLoS One 2013;8:e56241.
  • Mei PJ, Bai J, Liu H, Li C, Wu YP, Yu ZQ, et al. RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. J Cancer Res Clin Oncol 2011;137:1823–1830
  • Hsu PI, Hsieh HL, Lee J, Lin LF, Chen HC, Lu PJ, et al. Loss of RUNX3 expression correlates with differentiation, nodal metastasis, and poor prognosis of gastric cancer. Ann Surg Oncol 2009;16:1686–1694
  • Hu Q, Yu L, Chen R, Wang YL, Ji L, Zhang Y, et al. 5-aza-2′-deoxycytidine improves the sensitivity of endometrial cancer cells to progesterone therapy. Int J Gynecol Cancer 2012;22:951–959.
  • Yang J, Zhu XB, He LX, Gu ZW, Jin MZ, Ji WY. Clinical significance of epigenetic silencing re-expression of O6-methylguanine DNA methyltransferase using epigenetic agents in laryngeal carcinoma. Oncol Lett 2015;9:35–42.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.