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Original Article

Aging of Natural and Acquired Immunity of Mice. I. Decreased Natural Killer Cell Function and Hybrid Resistance

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Pages 15-24 | Published online: 11 Jun 2009

References

  • Enstrom J E. Cancer mortality among low-risk populations. UCLA (Univ Calif Los Angeles) Cancer Cent Bull 1979; 6: 3–22
  • Burnet F M. The concept of immunological surveillance. Prog Exp Tumor Res 1970; 13: 1–27
  • Bennett M. Effect of age on immune function in terms of chemically induced cancers. Environ Health Perspect 1979; 29: 17–22
  • Callard R E, Groth B F, St, Basten A, McKenzie I F C. Immune function in aged mice. V. Role of suppressor cells. J Immunol 1980; 124: 51–58
  • Callard R E, Basten A, Blanden R V. Loss of immune competence with age may be due to a qualitative abnormality in lymphocyte membranes. Nature (London) 1979; 281: 218–220
  • Goodman S A, Makinoden T. Effect of age on cell-mediated immunity in long-lived mice. Clin Exp Immunol 1975; 19: 533–542
  • Hirano T, Nordin A. Age-associated decline in the in vitro development of cytotoxic lymphocytes in NZB Mice. J Immunol 1976; 117: 1093–1098
  • Kay M M B, Makinodan T. Immunobiology of aging: Evaluation of current status. Clin Immunol Immunopathol 1976; 6: 394–413
  • Makinodan T, Peterson W J. Relative antibody-forming capacity of spleen cells as a function of age. Proc Natl Acad Sci (USA) 1962; 48: 234–238
  • Peterson W J, Makinodan T. Autoimmunity in aged mice; occurrence of autoagglutinating factors in the blood of aged mice with medium and long life spans. Clin Exp Immunol 1972; 12: 273–290
  • Price G B, Makinoden T. Immunologic deficiencies in senescence I. Characterization of intrinsic deficiencies. J Immunol 1972; 108: 403–412
  • Roder J C, Duwe A K, Bell D A, Singhal S K. Immunological senescence I. The role of suppressor cells. Immunology 1978; 35: 837–847
  • Shigemoto S, Kishimoto S, Yamamura Y. Change of cell-mediated cytotoxicity with aging. II. Analysis of the cellular mechanisms involved in the deficient antibody response in old mice. J Immunol 1975; 115: 307–309
  • Stutman O. Cell-mediated immunity and aging. Fed Proc Fed Am Soc Exp Biol 1974; 33: 2028–2035
  • Weksler M E, Innes J B, Goldstein G. Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice and reversal with thymopoietin. J Exp Med 1978; 148: 996–1006
  • Yunis E J, Greenberg L J. Immunopathology of aging. Fed Proc Fed Am Soc Exp Biol 1974; 33: 2017–2019
  • Walford R. Immunologic theory of aging: current status. Fed Proc Fed Am Soc Exp Biol 1974; 33: 2020–2027
  • Giovanella B C, Stehlin J S. Heterotransplantation of human malignant tumors in “nude” thymusless mice I. Breeding and maintenance of “nude” mice. J Natl Cancer Inst 1973; 51: 615–619
  • Stutman O. Tumor development after 3-methylcholanthrene in immunologically deficient athymic nude mice. Science 1974; 183: 534–536
  • Herberman R B, Holden H T. Natural cell-mediated immunity. Adv Cancer Res. 1978; 27: 305–377
  • Fitzgerald P A, Bennett M. Aging of natural and acquired immunity of mice. II. Decreased T-cell responses to syngeneic tumor cells and parental-strain spleen cells. Cancer Invest, (following paper) 1983; 1: 00–00
  • Bennett M, Baker E E, Eastcott J W, Kumar V, Yonkosky D. Selective elimination of marrow precursors with the bone seeking isotope 89Sr; implications for hemopoiesis, lymphopoiesis, viral leukemogenesis and infection. J Reticuloen-dothel Soc 1976; 20: 71–87
  • Seaman W E, Blackmail M A, Gundhert T D, Robinson J R, Loeb J, Talal N. -Estradiol reduces natural killer cells in mice. J Immunol 1978; 121: 2193–2198
  • Seaman W E, Gundhart T D, Greenspan J S, Blackman M A, Talal N. Natural killer cells, bone and the bone marrow: studies in estrogen-treated mice and in congenitally osteopetrotic (mi/mi) mice. J Immunol 1979; 122: 2541–2547
  • Seaman W E, Merigan T C, Talal N. Natural killing in estrogen-treated mice responds poorly to poly I:C despite normal stimulation of circulating interferon. J Immunol 1979; 123: 2903–2905
  • Bennett M. Prevention of marrow allograft rejection with radioactive strontium: Evidence for marrow-dependent effector cells. J Immunol 1973; 110: 510–516
  • Rossi G B, Cudkowicz G, Friend C. Evidence for transformation of spleen cells one day after infection of mice with Friend leukemia virus. J Exp Med 1970; 131: 765–781
  • Kumar V, Bennett M, Eckner R J. Mechanisms of genetic resistance to Friend virus leukemia in mice. I. Role of 89Sr-sensitive effective cells responsible for rejection of bone marrow allografts. J Exp Med 1974; 139: 1093–1109
  • Kumar V, Benz-Ezra J, Bennett M, Sonnenfeld G. Natural killer cells in mice treated with 89Sr; normal target-binding cell numbers but inability to kill even after interferon administration. J Immunol 1979; 123: 1832–1838
  • Haller O, Wigzell H. Suppression of natural killer activity with radioactive strontium: effector cells are marrow-dependent. J Immunol 1977; 118: 1503–1506
  • Lust J, Kumar V, Barton R, Bartlett S, Bennett M. Heterogeneity of natural killer (NK) cells in the mouse. J Exp Med 1981; 154: 306–317
  • Kumar V, Bennett M. Mechanism of genetic resistance to Friend leukemia virus in mice. II. Resistance to suppression of mitogen responsive lymphocytes mediated by marrow dependent (M) cells. J Exp Med 1976; 143: 713–727
  • Kumar V, Caruso T, Bennett M. Mechanisms of genetic resistance to Friend virus leukemia III Susceptibility of mitogen-responsive lymphocytes mediated by T cells. J Exp Med 1976; 143: 728–740
  • Merluzzi V J, Levy E M, Kumar V, Bennett M, Cooper-band S R. In vitro activation of suppressor cells from spleens of mice treated with radioactive strontium. J Immunol 1978; 121: 505–512
  • Staats J. Standardized nomenclature for inbred strains of mice: Seventh listing. Cancer Res. 1980; 40: 2083–2128
  • Sonnenfeld G, Mandel A D, Merigan T C. The immunosuppressive effect of type II mouse interferon preparations on antibody production. Cell Immunol 1977; 34: 193–206
  • Roder J, Kiessling R. Target-effector interaction in the natural killer cell system. I. covariance and genetic control of cytolytic and target-cell-binding subpopulations in the mouse. Scand J Immunol 1978; 8: 135–142
  • Julius M H, Simpson E, Herzenberg L. A rapid method for isolation of functional thymus derived murine lymphocytes. Eur J Immunol 1975; 3: 645–649
  • Djeu J Y, Heinbaugh J A, Holden H T, Herberman R B. Augmentation of mouse natural killer cell activity by interferon and interferon inducers. J Immunol 1979; 122: 175–181
  • Gidlund M, Orn A, Wigzell H, Senik A, Gresser L. Enhanced NK cell activity in mice injected with interferon and interferon inducers. Nature (London) 1978; 273: 759–761
  • Bennett M. Rejection of marrow allografts: Importance of H-2 homozygosity of donor cells. Transplantation 1972; 14: 289–298
  • Bennett M, Melvold R W, Kohn H E. Bone marrow cell grafts involving the H-2D and H-2L mutant haplotypes. Immunogenetics 1980; 10: 273–281
  • Kaminsky S, Cudkowicz G. Natural killing and resistance to marrow grafts: correlations in four beige mutant mouse lines. Fed Proc Fed Am Soc Exp Biol 1980; 39: 359
  • Cudkowicz G, Hochman P S. Do natural killer cells engage in regulated reactions against self to ensure homeostasis. Immunol Rev 1979; 44: 13–41
  • Chertov J L, Gurevitch O A. Age-related changes in hemopoietic microenvironment. Enhanced growth of hemopoietic stroma and weakened genetic resistance to hemopoietic cells in old mice. Gerontologist 1981; 16: 195–198
  • Harrison D E. F1 Hybrid resistance: long term systemic effects sensitive to irradiation and age. Immunogenetics 1981; 13: 177–187
  • Fitzgerald P A, Bennett M. Immunosensecence: loss of natural killer cell function, responses to syngeneic tumor cells, and hybrid resistance in vivo and in vitro. Fed Proc Fed Am Soc Exp Biol 1980; 39: 2818
  • Cudkowicz G, Bennett M. Peculiar immunobiology of bone marrow allografts. II. Rejection of parental grafts by resistant F1 hybrid mice. J Exp Med 1971; 134: 1513–1528
  • Hochman P S, Cudkowicz G. Suppression of natural cytotoxicity by spleen cells of hydrocortisone-treated mice. J Immunol 1978; 123: 968–976
  • Kiessling R, Hochman P S, Haller O, Shearer G M, Wigzell H, Cudkowicz G. Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts. Eur J Immunol 1977; 7: 655–663
  • Lotzova E, Cudkowicz G. Abrogation of resistance to bone marrow grafts by silica particles. J Immunol 1974; 113: 798–803
  • Levy E M, Bennett M, Kumar V, Fitzgerald P, Cooper-band S R. Adoptive transfer of spleen cells from mice treated with radioactive strontium: suppressor cells, natural killer cells, and “hybrid resistance” in recipient mice. J Immunol 1980; 124: 611–618

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