73
Views
29
CrossRef citations to date
0
Altmetric
Original Article

A Model for Tumor Response to Chemotherapy:An Integration of the Stem Cell and Somatic Mutation Hypotheses

&
Pages 553-564 | Published online: 11 Jun 2009

References

  • Goldie J H, Coldman A J. The genetic origin of drag resistance in neoplasms: Implications for systemic therapy. Cancer Res 1984; 44: 3643–3653
  • Ling V. Genetic basis of drug resistance in mammalian cells. Drug and Hormone Resistance in Neoplasia, N Bruchovsky, J H Goldie. CRC Press, Boca Raton, FL 1982; Vol. 1
  • Goldie J H, Coldman A J. A mathematical model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treat Rep 1979; 63: 1727–1733
  • Goldie J H, Coldman A J, Gudauskas G A. Rationale for the use of alternating non-cross resistant chemotherapy. Cancer Treat Rep 1982; 66: 439–449
  • Coldman A J, Goldie J H. A model for the resistance of tumor cells to cancer chemotherapeutic agents. Math Biosci 1983; 65: 291–307
  • Nowell P C. Genetic instability in cancer cells: Relationship to tumors cell heterogeneity. Tumor Cell Heterogeneity Origins and Implications, A H Owens, D S Coffey, S B Baylin. Academic Press Inc., New York 1982; 351–369
  • Nowell P C. Tumor progression and clonal evolution: The role of genetic instability. Chromosome Mutation and Neoplasia, J German. Alan R. Liss, New York 1983; 413–432
  • Fidler I J, Poste E G. The heterogeneity of metastatic properties in malignant tumor cells and regulation of the metastatic phe-notype. Tumor Cell Heterogeneity Origins and Implications, A H Owens, D F Coffey, S B Baylin. Academic Press Inc., New York 1982; 127–146
  • Hill B T. Biochemical and cell kinetic aspects to drug resistance. Drug and Hormone Resistance in Neoplasia, N Bruchovsky, J H Goldie. CRC Press, Boca Raton, Fl 1982; Vol. 1
  • Luria S E, Delbruck M. Mutation of bacteria from virus sensitivity to virus resistance. Genetics 1943; 28: 491–511
  • Siminovitch L. On the nature of hereditable variation in cultured somatic cells. Cell 1976; 7: 1–11
  • Skipper H E. Some thoughts regarding a recent publication by Goldie and Coldman entitled “A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate”. Booklet 9. Southern Research Institute, Birmingham, AL 1980
  • DeVita V T, Jr. The relationship between tumor mass and resistance to chemotherapy. Cancer 1983; 51: 1209–1220
  • Schabel F M, Jr, Skipper H E, Trader M W, Laster W R, Jr, Corbett T H, Griswold D P. Concepts for controlling drug resistant tumor cells. Breast Cancer Experimental and Clinical Aspects, H T Moundren, T Palshol. Pergamon Press, Oxford 1980; 199–212
  • Santoro A, Bonadonna G, Bonfant V, Valagussa P. Alternating drug combinations in the treatment of advanced Hodgkin's disease. N Engl J Med 1982; 306: 770–775
  • Bush R S, Hill R P. Biologic discussion augmenting radiation effects in model systems. Laryngoscope 1975; 85: 119–1133
  • Bush R S, DeBoer G, Hill R P. Long term survival with gynecological cancer. Prolonged Arrest of Cancer, B A Stoll. John Wiley and Sons Inc., New York 1982; 27–58
  • Buick R N, Mackillop W J. Measurement of self-renewal in culture of clonogenic cells from human ovarian carcinoma. Br J Cancer 1981; 44: 349–355
  • Salmon S E, Alberts D S, Meyskens F L, Jr., Durie B GM, Jones S E, Soehalen B, Young L, Chen H S, Moon T E. Clinical correlations of in vitro drug sensitivity. Cloning of Human Tumor Stem Cells, S E Salmon. Alan R. Liss, New York 1980; 223–246
  • Goldie J H, Coldman A J. Quantitative model for multiple levels of drug resistance in clinical tumors. Cancer Treat Rep 1983; 67: 923–931
  • Schackney S E, McCormack G W, Cuchural G J, Jr. Growth rate patterns of solid tumors and their relation to responsiveness to therapy: An analytical review. Ann Intern Med 1978; 89: 107–121
  • Baskan F, Rosenberg R N, Vaithilingham D. Correlation of double minute chromosomes with unstable multidrug crossresistance in uptake mutants of neuroblastoma cells. Proc Natl Acad Sci USA 1981; 78: 3654–3658
  • Kaufman R J, Brown P C, Schimke R T. Amplified dihydrofolate reductase genes in unstable methotrexate resistant cells are associated with double minute chromosomes. Proc Natl Acad Sci USA 1979; 76: 5669–5673
  • Tischfield J A, Trill J J, Lee Y I, Coy K, Tylor M W. Genetic instability at the adenine phosphoribosyl transferase locus in mouse L cells. Molec Cell Biol 1982; 2: 250–257
  • Ziegler J L, Deisseroth A B, Applebaum F R, Garw R G. Bur-kitt's lymphoma-a model for intensive chemotherapy. Semin Oncol 1977; 4: 317–323
  • Vaugn W P, Karp J E, Burke P J. Long chemotherapy free remissions after single cycle timed sequential chemotherapy for acute myelocytic leukemia. Cancer 1980; 45: 859–865
  • MacKillop W J, Ciampi A, Till J E, Buick R N. A stem cell model of human tumor growth: Implications for tumor cell clonogenic assays. JNCI 1983; 70: 9–16
  • Bruce W R, Vander Gaag H. A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature 1963; 199: 79–80
  • Buick R N, Chang U A, Messner H A, Curtis J E, McCulloch E A. Self renewal capacity of leukemic blast progenitor cells. Cancer Res 1981; 41: 4849–4852
  • Tsururo T. Reversal of acquired resistance to Vinca alkaloids and anthracycline antibiotics. Cancer Treat Rep 1983; 67: 889–894
  • Hryniuk W, Bush H. The importance of dose intensity in the chemotherapy of breast cancer. J Clin Oncol 1984; 2: 1281–1288
  • Klimo P, Connors J M. A 12 week program for the treatment of advanced diffuse large cell lymphoma. Ann Intern Med 1985, in press

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.