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Cancer Investigation Volume 11, 1993 - Issue 2
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Original Article

Combination Treatment of Acute Myeloblastic Leukemia with rhGM-CSF and Standard Induction Chemotherapy

P. Valent Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
Ch. Sillaber Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
K. Geissler Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
M. Andreeff Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
A. Tafuri Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
L. Vieder Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
G. Schulz Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
,
K. Lechner Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
&
P. Bettelheim Division of Hematology First Medical Department, University of Vienna Vienna, Austria; Department of Medicine Memorial Sloan Kettering Cancer Center New York, New York Behring Company Marburg, Germany
 show all
Pages 229-234 | Published online: 11 Jun 2009

References

  • Metcalf D. The granulocyte macrophage colony stimulating factor. Science 1985; 229: 16
  • Clark S C, Kamen R. The human hematopoietic colony stimulating factors. Science 1987; 236: 1229
  • Nienhuis W. Hematopoietic growth factors. N Engl J Med 1988; 318: 916
  • Antman K S, Griffin J D, Elias A. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N Engl J Med 1988; 319: 593
  • Brandt J S, William P P, Atwatcr S K. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose cheniotherapy and au-tologous bone marrow transplantation. N Engl J Med 1988; 318: 869
  • Tafuri A, Hegewiach SV, Souza L, Andreef M. Stimulation of leukemic blast cells in vitro by colony-stimulating factors (G-CSF, GM-CSF) and interleukin 3 (IL-3): evidence of recruitment and increased cell killing with cytosine-arabinoside (Ara-C) (abstr). Blood 1988; 72: 105
  • Bhalla K, Birkhofer M, Arlin Z. Effects of recombinant GM-CSF on the metabolism of cytosine-arabinoside in normal and leukemic human bone marrow cells. Leukemia 1988; 2: 810
  • Cannistra S A, Groschek P, Griffin J D. GM-CSF enhances the cytotoxic effects of cytosine-arabinoside in acute rnyeloblastic leukemia and in the myeloid blast crisis phase of chronic myeloid leukemia. Blood 1988; 72: 193a
  • Bettelheim P, Muhrn M, Andreeff M. GM-CSF during remission induction for acute myelogenous leukemia. He-matological Growth Factors in Clinical Applications, R F. Mertelsmann. Marcel Dekker, Hemnann 1990; 401–420
  • Bettelheirn P, Valent P, Andreeff M. RhGM-CSF in combination with standard induction chemotherapy in de novo acute myeloid leukemia. Blood 1991; 77: 700
  • Gasson J C, Kaufrnann S, Weisbart R H. High affinity binding of granulocyte-macrophage colony-stimulating factor to normal and leukemic myeloid cells. Proc Natl Acad Sci (USA) 1986; 83: 669

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